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Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

We combine two recently proposed nonparametric difference-in-differences methods, extending them to enable the examination of treatment effect heterogeneity in the staggered adoption setting using machine learning. The proposed method,…

Econometrics · Economics 2023-10-19 Julia Hatamyar , Noemi Kreif , Rudi Rocha , Martin Huber

Understanding how treatment effects vary on individual characteristics is critical in the contexts of personalized medicine, personalized advertising and policy design. When the characteristics are of practical interest are only a subset of…

Methodology · Statistics 2023-05-03 Peng Wu , ShaSha Han , Xingwei Tong , Runze Li

This paper considers identifying and estimating causal effect parameters in a staggered treatment adoption setting -- that is, where a researcher has access to panel data and treatment timing varies across units. We consider the case where…

Econometrics · Economics 2023-08-08 Brantly Callaway , Emmanuel Selorm Tsyawo

We consider learning personalized assignments to one of many treatment arms from a randomized controlled trial. Standard methods that estimate heterogeneous treatment effects separately for each arm may perform poorly in this case due to…

Machine Learning · Statistics 2023-11-02 Rahul Ladhania , Jann Spiess , Lyle Ungar , Wenbo Wu

Offline policy learning aims to discover decision-making policies from previously-collected datasets without additional online interactions with the environment. As the training dataset is fixed, its quality becomes a crucial determining…

Machine Learning · Computer Science 2024-02-16 Qiang Wang , Yixin Deng , Francisco Roldan Sanchez , Keru Wang , Kevin McGuinness , Noel O'Connor , Stephen J. Redmond

Attrition is a common and potentially important threat to internal validity in treatment effect studies. We extend the changes-in-changes approach to identify the average treatment effect for respondents and the entire study population in…

Econometrics · Economics 2024-03-29 Dalia Ghanem , Sarojini Hirshleifer , Désiré Kédagni , Karen Ortiz-Becerra

Machine learning models are often personalized with categorical attributes that are protected, sensitive, self-reported, or costly to acquire. In this work, we show models that are personalized with group attributes can reduce performance…

Machine Learning · Statistics 2023-07-25 Vinith M. Suriyakumar , Marzyeh Ghassemi , Berk Ustun

Machine learning systems have been widely used to make decisions about individuals who may behave strategically to receive favorable outcomes, e.g., they may genuinely improve the true labels or manipulate observable features directly to…

Artificial Intelligence · Computer Science 2024-10-30 Tian Xie , Zhiqun Zuo , Mohammad Mahdi Khalili , Xueru Zhang

Statistical heterogeneity is a root cause of tension among accuracy, fairness, and robustness of federated learning (FL), and is key in paving a path forward. Personalized FL (PFL) is an approach that aims to reduce the impact of…

Machine Learning · Computer Science 2024-07-24 Shengkun Zhu , Jinshan Zeng , Sheng Wang , Yuan Sun , Xiaodong Li , Yuan Yao , Zhiyong Peng

We study a Federated Reinforcement Learning (FedRL) problem in which $n$ agents collaboratively learn a single policy without sharing the trajectories they collected during agent-environment interaction. We stress the constraint of…

Machine Learning · Computer Science 2022-04-07 Hao Jin , Yang Peng , Wenhao Yang , Shusen Wang , Zhihua Zhang

We consider the estimation of heterogeneous treatment effects with arbitrary machine learning methods in the presence of unobserved confounders with the aid of a valid instrument. Such settings arise in A/B tests with an intent-to-treat…

Econometrics · Economics 2019-06-07 Vasilis Syrgkanis , Victor Lei , Miruna Oprescu , Maggie Hei , Keith Battocchi , Greg Lewis

A fundamental limitation of causal inference in observational studies is that perceived evidence for an effect might instead be explained by factors not accounted for in the primary analysis. Methods for assessing the sensitivity of a…

Methodology · Statistics 2018-09-14 Colin B. Fogarty

Some patients benefit from a treatment while others may do so less or do not benefit at all. We have previously developed a two-stage network meta-regression prediction model that synthesized randomized trials and evaluates how treatment…

The process of infection of a host is complex, influenced by factors such as microbial variation within and between hosts as well as differences in dose across hosts. This study uses dose-response and within-host microbial infection models…

Populations and Evolution · Quantitative Biology 2025-04-10 Francisco J. Perez-Reche

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Objective: To compare different risk-based methods for optimal prediction of treatment effects. Methods: We simulated RCT data using diverse assumptions for the average treatment effect, a baseline prognostic index of risk (PI), the shape…

We seek measurable properties of AI agents that make them better or worse teammates from the subjective perspective of human collaborators. Our experiments use the cooperative card game Hanabi -- a common benchmark for AI-teaming research.…

Human-Computer Interaction · Computer Science 2025-03-21 Ho Chit Siu , Jaime D. Peña , Yutai Zhou , Ross E. Allen

With the timely formation of personalized intervention plans based on high-dimensional heterogeneous time series information becoming an important challenge in the medical field today, electronic medical records, wearables, and other…

Artificial Intelligence · Computer Science 2025-04-29 Dingxin Lu , Shurui Wu , Xinyi Huang

In most real-world systems units are interconnected and can be represented as networks consisting of nodes and edges. For instance, in social systems individuals can have social ties, family or financial relationships. In settings where…

Methodology · Statistics 2018-07-31 Laura Forastiere , Fabrizia Mealli , Albert Wu , Edoardo Airoldi
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