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The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

In computational pathology, understanding and generation have evolved along disparate paths: advanced understanding models already exhibit diagnostic-level competence, whereas generative models largely simulate pixels. Progress remains…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Minghao Han , Yichen Liu , Yizhou Liu , Zizhi Chen , Jingqun Tang , Xuecheng Wu , Dingkang Yang , Lihua Zhang

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Semantic image synthesis (SIS) aims to generate realistic images that match given semantic masks. Despite recent advances allowing high-quality results and precise spatial control, they require a massive semantic segmentation dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Jungwoo Chae , Hyunin Cho , Sooyeon Go , Kyungmook Choi , Youngjung Uh

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Facial Image inpainting aim is to restore the missing or corrupted regions in face images while preserving identity, structural consistency and photorealistic image quality, a task specifically created for photo restoration. Though there…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Abhigyan Bhattacharya , Hiranmoy Roy , Debotosh Bhattacharjee

Medical image synthesis has become an essential strategy for augmenting datasets and improving model generalization in data-scarce clinical settings. However, fine-grained and controllable synthesis remains difficult due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Shuhan Ding , Jingjing Fu , Yu Gu , Naiteek Sangani , Mu Wei , Paul Vozila , Nan Liu , Jiang Bian , Hoifung Poon

The global population is aging rapidly, and aging is a major risk factor for various diseases. It is an important task to predict how each individual's brain will age, as the brain supports many human functions. This capability can greatly…

Neurons and Cognition · Quantitative Biology 2025-12-05 Yifan Li , Javad Sohankar , Ji Luo , Jing Li , Yi Su

Enabling highly secure applications (such as border crossing) with face recognition requires extensive biometric performance tests through large scale data. However, using real face images raises concerns about privacy as the laws do not…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Marcel Grimmer , Haoyu Zhang , Raghavendra Ramachandra , Kiran Raja , Christoph Busch

Inpainting, the process of filling missing or corrupted image parts, has broad applications in medical imaging. However, generating anatomically accurate synthetic polyp images for clinical AI is a largely underexplored problem. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Duy-Bao Bui , Hoang-Khang Nguyen , Thao Thi Phuong Dao , Kim Anh Phung , Tam V. Nguyen , Justin Zhan , Minh-Triet Tran , Trung-Nghia Le

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P

Image inpainting approaches have achieved significant progress with the help of deep neural networks. However, existing approaches mainly focus on leveraging the priori distribution learned by neural networks to produce a single inpainting…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Wangbo Yu , Jinhao Du , Ruixin Liu , Yixuan Li , Yuesheng zhu

While high-resolution pathology images lend themselves well to `data hungry' deep learning algorithms, obtaining exhaustive annotations on these images is a major challenge. In this paper, we propose a self-supervised CNN approach to…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Navid Alemi Koohbanani , Balagopal Unnikrishnan , Syed Ali Khurram , Pavitra Krishnaswamy , Nasir Rajpoot

Tumor segmentation plays a critical role in histopathology, but it requires costly, fine-grained image-mask pairs annotated by pathologists. Thus, synthesizing histopathology data to expand the dataset is highly desirable. Previous works…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Hong Liu , Haosen Yang , Evi M. C. Huijben , Mark Schuiveling , Ruisheng Su , Josien P. W. Pluim , Mitko Veta

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 John R. McNulty , Lee Kho , Alexandria L. Case , Charlie Fornaca , Drew Johnston , David Slater , Joshua M. Abzug , Sybil A. Russell

Recent advances in deep learning and on-device inference could transform routine screening for skin cancers. Along with the anticipated benefits of this technology, potential dangers arise from unforeseen and inherent biases. A significant…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Ko Watanabe , Stanislav Frolov , Aya Hassan , David Dembinsky , Adriano Lucieri , Andreas Dengel

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

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