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We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics that promote the onset of self-sustained oscillations. By…

Quantitative Methods · Quantitative Biology 2022-06-23 Yaron Ben-Ami , George W. Atkinson , Joe M. Pitt-Francis , Philip K. Maini , Helen M. Byrne

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Existing deep learning-based surrogate models facilitate efficient data generation, but fall short in uncertainty quantification, efficient parameter space exploration, and reverse prediction. In our work, we introduce SurroFlow, a novel…

Machine Learning · Computer Science 2024-07-19 Jingyi Shen , Yuhan Duan , Han-Wei Shen

Over the past decade, several studies have explored the potential of magnetic resonance fingerprinting (MRF) for the quantification of brain hemodynamics, oxygenation, and perfusion. Recent advances in simulation models and reconstruction…

Signal Processing · Electrical Eng. & Systems 2025-12-16 T. Coudert , A. Delphin , A. Barrier , E L Barbier , B. Lemasson , J M Warnking , T. Christen

We present a new turbulent data reconstruction method with supervised machine learning techniques inspired by super resolution and inbetweening, which can recover high-resolution turbulent flows from grossly coarse flow data in space and…

Fluid Dynamics · Physics 2021-01-25 Kai Fukami , Koji Fukagata , Kunihiko Taira

Simulation of fluid flow in porous media has many applications, from the micro-scale (cell membranes, filters, rocks) to macro-scale (groundwater, hydrocarbon reservoirs, and geothermal) and beyond. Direct simulation of flow in porous media…

Fluid Dynamics · Physics 2020-04-27 Ying Da Wang , Traiwit Chung , Ryan T. Armstrong , Peyman Mostaghimi

Understanding the sequence of cognitive operations that underlie decision-making is a fundamental challenge in cognitive neuroscience. Traditional approaches often rely on group-level statistics, which obscure trial-by-trial variations in…

Neurons and Cognition · Quantitative Biology 2025-04-15 Rick den Otter , Gabriel Weindel , Sjoerd Stuit , Leendert van Maanen

Cerebral small vessel disease (CSVD) is a major vascular contributor to cognitive impairment in ageing, including dementias. Imaging remains the most promising method for in vivo studies of CSVD. To replace the subjective and laborious…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Jiyang Jiang , Dadong Wang , Yang Song , Perminder S. Sachdev , Wei Wen

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…

Quantitative Methods · Quantitative Biology 2026-02-17 Reza Bozorgpour , Jacob R. Rammer

Collateral circulation results from specialized anastomotic channels which are capable of providing oxygenated blood to regions with compromised blood flow caused by ischemic injuries. The quality of collateral circulation has been…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Giles Tetteh , Fernando Navarro , Johannes Paetzold , Jan Kirschke , Claus Zimmer , Bjoern H. Menze

We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden

With the rapid increase of available data for complex systems, there is great interest in the extraction of physically relevant information from massive datasets. Recently, a framework called Sparse Identification of Nonlinear Dynamics…

Machine Learning · Statistics 2018-04-18 Lorenzo Boninsegna , Feliks Nüske , Cecilia Clementi

4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Simone Saitta , Marcello Carioni , Subhadip Mukherjee , Carola-Bibiane Schönlieb , Alberto Redaelli

Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create these models, providing a predictive tool for clinicians.…

Turbulent flow over permeable interface is omnipresent featuring complex flow topology. In this work, a data driven, end to end machine learning model has been developed to model the turbulent flow in porous media. For the same, we have…

Fluid Dynamics · Physics 2023-11-28 Xu Chu , Sandeep Pandey

Segmentation of brain arterio-venous malformations (bAVMs) in 3D rotational angiographies (3DRA) is still an open problem in the literature, with high relevance for clinical practice. While deep learning models have been applied for…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Camila García , Yibin Fang , Jianmin Liu , Ana Paula Narata , José Ignacio Orlando , Ignacio Larrabide

We apply supervised machine learning techniques to a number of regression problems in fluid dynamics. Four machine learning architectures are examined in terms of their characteristics, accuracy, computational cost, and robustness for…

Fluid Dynamics · Physics 2020-03-18 Kai Fukami , Koji Fukagata , Kunihiko Taira

The manual evaluation, classification and counting of biological objects demands for an enormous expenditure of time and subjective human input may be a source of error. Investigating the shape of red blood cells (RBCs) in microcapillary…

Biological Physics · Physics 2018-06-22 Alexander Kihm , Lars Kaestner , Christian Wagner , Stephan Quint

Whilst grading neurovascular abnormalities is critical for prompt surgical repair, no statistical markers are currently available for predicting the risk of adverse events, such as stroke, and the overall resilience of a network to vascular…

Quantitative Methods · Quantitative Biology 2019-10-30 Stefano Moriconi , Rafael Rehwald , Maria A. Zuluaga , H. Rolf Jäger , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso