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In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

For the advancements of time series classification, scrutinizing previous studies, most existing methods adopt a common learning-to-classify paradigm - a time series classifier model tries to learn the relation between sequence inputs and…

Machine Learning · Computer Science 2024-03-20 Mingyue Cheng , Yiheng Chen , Qi Liu , Zhiding Liu , Yucong Luo

Large Language Models (LLMs) have seen significant use in domains such as natural language processing and computer vision. Going beyond text, image and graphics, LLMs present a significant potential for analysis of time series data,…

Machine Learning · Computer Science 2024-05-08 Xiyuan Zhang , Ranak Roy Chowdhury , Rajesh K. Gupta , Jingbo Shang

Large language models (LLMs) are increasingly used in healthcare, yet standardised benchmarks for evaluating guideline-based clinical reasoning are missing. This study introduces a validated dataset derived from publicly available…

Computation and Language · Computer Science 2025-11-04 Qing Ding , Eric Hua Qing Zhang , Felix Jozsa , Julia Ive

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive…

Signal Processing · Electrical Eng. & Systems 2026-03-02 Surajit Das , Maxine Tan

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…

Machine Learning · Computer Science 2025-01-17 Wasif Khan , Seowung Leem , Kyle B. See , Joshua K. Wong , Shaoting Zhang , Ruogu Fang

Recently, there has been a growing interest in time series foundation models that generalize across different downstream tasks. A key to strong foundation models is a diverse pre-training dataset, which is particularly challenging to…

Machine Learning · Computer Science 2024-12-10 Songkang Wen , Vasilii Feofanov , Jianfeng Zhang

Foundation models have achieved remarkable success across diverse machine-learning domains through large-scale pretraining on large, diverse datasets. However, pretraining on such datasets introduces significant challenges due to…

Machine Learning · Computer Science 2025-04-16 Peiliang Gong , Emadeldeen Eldele , Min Wu , Zhenghua Chen , Xiaoli Li , Daoqiang Zhang

Pre-trained Large Language Models (LLMs) encapsulate large amounts of knowledge and take enormous amounts of compute to train. We make use of this resource, together with the observation that LLMs are able to transfer knowledge and…

Machine Learning · Computer Science 2025-01-14 Malcolm L. Wolff , Shenghao Yang , Kari Torkkola , Michael W. Mahoney

In recent years, generative diffusion models have achieved a rapid paradigm shift in deep generative models by showing groundbreaking performance across various applications. Meanwhile, structured data, encompassing tabular and time series…

Machine Learning · Computer Science 2023-07-11 Heejoon Koo , To Eun Kim

Machine learning for early syndrome diagnosis aims to solve the intricate task of predicting a ground truth label that most often is the outcome (effect) of a medical consensus definition applied to observed clinical measurements (causes),…

Machine Learning · Computer Science 2024-08-27 Michael Staniek , Marius Fracarolli , Michael Hagmann , Stefan Riezler

In many machine learning for healthcare tasks, standard datasets are constructed by amassing data across many, often fundamentally dissimilar, sources. But when does adding more data help, and when does it hinder progress on desired model…

Machine Learning · Computer Science 2024-08-09 Judy Hanwen Shen , Inioluwa Deborah Raji , Irene Y. Chen

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Recent work on time-series models has leveraged self-supervised training to learn meaningful features and patterns in order to improve performance on downstream tasks and generalize to unseen modalities. While these pretraining methods have…

Machine Learning · Computer Science 2026-04-10 Paul Quinlan , Qingguo Li , Xiaodan Zhu

Foundation models, particularly Large Language Models (LLMs), have revolutionized text and video processing, yet time series data presents distinct challenges for such approaches due to domain-specific features such as missing values,…

Machine Learning · Computer Science 2025-02-12 Defu Cao , Wen Ye , Yizhou Zhang , Yan Liu

In practice, it is very demanding and sometimes impossible to collect datasets of tagged data large enough to successfully train a machine learning model, and one possible solution to this problem is transfer learning. This study aims to…

Machine Learning · Computer Science 2022-01-13 Erik Otović , Marko Njirjak , Dario Jozinović , Goran Mauša , Alberto Michelini , Ivan Štajduhar

The hypothesis that computational models can be reliable enough to be adopted in prognosis and patient care is revolutionizing healthcare. Deep learning, in particular, has been a game changer in building predictive models, thus leading to…

Machine Learning · Statistics 2019-06-17 Jayaraman J. Thiagarajan , Deepta Rajan , Prasanna Sattigeri

Removing the bias and variance of multicentre data has always been a challenge in large scale digital healthcare studies, which requires the ability to integrate clinical features extracted from data acquired by different scanners and…

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and…