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Purpose: Radiotherapy presents unique challenges and clinical requirements for longitudinal tumor and organ-at-risk (OAR) prediction during treatment. The challenges include tumor inflammation/edema and radiation-induced changes in organ…
Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images…
We propose a method to non-rigidly align a three-dimensional (3D) volumetric image with a two-dimensional (2D) planar image representing a projection of the deformed volume. The application in mind comes from biological studies in which 2D…
We introduce a novel profile-based patient clustering model designed for clinical data in healthcare. By utilizing a method grounded on constrained low-rank approximation, our model takes advantage of patients' clinical data and digital…
Contemporary interventional imaging lacks the real-time 3D guidance needed for the precise localization of mobile thoracic targets. While Cone-Beam CT (CBCT) provides 3D data, it is often too slow for dynamic motion tracking. Deep learning…
Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps…
In current clinical practice, noisy and artifact-ridden weekly cone-beam computed tomography (CBCT) images are only used for patient setup during radiotherapy. Treatment planning is done once at the beginning of the treatment using…
This study aims to investigate the effect of various beam geometries and dimensions of input data on the sparse-sampling streak artifact correction task with U-Nets for clinical CT scans as a means of incorporating the volumetric context…
To facilitate diagnosis on cardiac ultrasound (US), clinical practice has established several standard views of the heart, which serve as reference points for diagnostic measurements and define viewports from which images are acquired.…
The exponential growth of medical imaging has created significant challenges in data storage, transmission, and management for healthcare systems. In this vein, efficient compression becomes increasingly important. Unlike natural image…
This paper introduces a hybrid two-stage registration framework for reconstructing three-dimensional (3D) kidney anatomy from macroscopic slices, using CT-derived models as the geometric reference standard. The approach addresses the…
Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…
Organ motion poses an unresolved challenge in image-guided interventions. In the pursuit of solving this problem, the research field of time-resolved volumetric magnetic resonance imaging (4D MRI) has evolved. However, current techniques…
Accurate segmentation of the heart is essential for personalized blood flow simulations and surgical intervention planning. Segmentations need to be accurate in every spatial dimension, which is not ensured by segmenting data slice by…
Single-cell technologies generate high-dimensional point clouds of cells, enabling detailed characterization of complex patient states and treatment responses. Yet each patient is represented by an irregular point cloud rather than a simple…
Accurate geometric quantification of the human heart is a key step in the diagnosis of numerous cardiac diseases, and in the management of cardiac patients. Ultrasound imaging is the primary modality for cardiac imaging, however acquisition…
Accurately registering breast MR images from different time points enables the alignment of anatomical structures and tracking of tumor progression, supporting more effective breast cancer detection, diagnosis, and treatment planning.…
Accurate segmentation of pulmonary structures iscrucial in clinical diagnosis, disease study, and treatment planning. Significant progress has been made in deep learning-based segmentation techniques, but most require much labeled data for…
Purpose: To develop an algorithm for real-time volumetric image reconstruction and 3D tumor localization based on a single x-ray projection image for lung cancer radiotherapy. Methods: Given a set of volumetric images of a patient at N…
3D ultrasound (3DUS) becomes more interesting for target tracking in radiation therapy due to its capability to provide volumetric images in real-time without using ionizing radiation. It is potentially usable for tracking without using…