Related papers: Approximate peak time to time-domain fluorescence …
This paper proposes a direct inversion scheme for fluorescence diffuse optical tomography (FDOT) to reconstruct the location of a point target using the measured peak time of the temporal response functions. A sphere is defined for the…
In this work, an inverse problem on the determination of multiple coefficients arising from the time-domain diffuse optical tomography with fluorescence (DOT-FDOT) is investigated. We simultaneously recover the distribution of background…
A fast and robust algorithm for fluorescence diffuse optical tomography is proposed. We identify the location of a fluorescence target by assuming a cuboid. The proposed numerical method is verified by a numerical experiment and an in vivo…
This work considers the time-domain fluorescence diffuse optical tomography (FDOT). We recover the distribution of fluorophores in biological tissue by the boundary measurements. With the Laplace transform and the knowledge of complex…
Fluorescence molecular tomography (FMT) is a promising modality for non-invasive imaging of internal fluorescence agents in biological tissues especially in small animal models, with applications in diagnosis, therapy, and drug design. In…
This work considers the inverse dynamic source problem arising from the time-domain fluorescence diffuse optical tomography (FDOT). We recover the dynamic distributions of fluorophores in biological tissue by the one single boundary…
In fluorescence diffuse optical tomography (fDOT), the reconstruction of the fluorophore concentration inside the target body is usually carried out using a normalized Born approximation model where the measured fluorescent emission data is…
Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…
Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…
Light propagation through diffusive media can be described by the diffusion equation in a space-time domain. Further, fluorescence can be described by a system of coupled diffusion equations. This paper analyzes time-domain measurements,…
Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…
Ultrafast science and technology have brought in burgeoning opportunities to optical metrology, strong-field physics, non-equilibrium physics, etc., through light-matter interaction due to ever-advancing temporal resolution and peak power…
In this paper, we present a novel Newton-based extremum seeking controller for the solution of multivariable model-free optimization problems in static maps. Unlike existing asymptotic and fixed-time results in the literature, we present a…
We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference…
This paper introduces a multi-frequency factorization method for imaging a time-dependent source, specifically to recover its spatial support and the associated excitation instants. Using far-field data from two opposite directions, we…
We consider the problem of reconstructing one-dimensional point sources from their Fourier measurements in a bounded interval $[-\Omega, \Omega]$. This problem is known to be challenging in the regime where the spacing of the sources is…
This work studies the inverse problem of photoacoustic tomography (more precisely, the acoustic subproblem) as the identification of a space-dependent source parameter. The model consists of a wave equation involving a time-fractional…
We study analytically and numerically the mean fastest first-passage time (fFPT) to an immobile target for an ensemble of $N$ independent finite-speed random searchers driven by dichotomous noise and described by the telegrapher's equation.…
Fluorescence Lifetime Imaging Microscopy in the time domain is typically performed by recording the arrival time of photons either by using electronic time tagging or a gated detector. As such the temporal resolution is limited by the…
Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…