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In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Biomedical image segmentation is critical for accurate identification and analysis of anatomical structures in medical imaging, particularly in cardiac MRI. Manual segmentation is labor-intensive, time-consuming, and prone to errors,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Ting Yu Tsai , Li Lin , Shu Hu , Ming-Ching Chang , Hongtu Zhu , Xin Wang

For complex segmentation tasks, the achievable accuracy of fully automated systems is inherently limited. Specifically, when a precise segmentation result is desired for a small amount of given data sets, semi-automatic methods exhibit a…

Human-Computer Interaction · Computer Science 2019-09-04 Mario Amrehn , Stefan Steidl , Reinier Kortekaas , Maddalena Strumia , Markus Weingarten , Markus Kowarschik , Andreas Maier

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

Medical image annotation is a major hurdle for developing precise and robust machine learning models. Annotation is expensive, time-consuming, and often requires expert knowledge, particularly in the medical field. Here, we suggest using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Holger R Roth , Dong Yang , Ziyue Xu , Xiaosong Wang , Daguang Xu

Recent advancements have highlighted the Mamba framework, a state-space model known for its efficiency in capturing long-range dependencies with linear computational complexity. While Mamba has shown competitive performance in medical image…

Image and Video Processing · Electrical Eng. & Systems 2025-02-05 Weiren Zhao , Feng Wang , Yanran Wang , Yutong Xie , Qi Wu , Yuyin Zhou

Semantic segmentation with dense pixel-wise annotation has achieved excellent performance thanks to deep learning. However, the generalization of semantic segmentation in the wild remains challenging. In this paper, we address the problem…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Wei Zhou , Yukang Wang , Jiajia Chu , Jiehua Yang , Xiang Bai , Yongchao Xu

Source-Free Domain Adaptation (SFDA) is emerging as a compelling solution for medical image segmentation under privacy constraints, yet current approaches often ignore sample difficulty and struggle with noisy supervision under domain…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Quang-Khai Bui-Tran , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Ba-Thinh Lam , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

The task of image segmentation is inherently noisy due to ambiguities regarding the exact location of boundaries between anatomical structures. We argue that this information can be extracted from the expert annotations at no extra cost,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Mobarakol Islam , Ben Glocker

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Unsupervised Domain Adaptation (UDA) is essential for deploying medical segmentation models across diverse clinical environments. Existing methods are fundamentally limited, suffering from semantically unaware feature alignment that results…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Linkuan Zhou , Yinghao Xia , Yufei Shen , Xiangyu Li , Wenjie Du , Cong Cong , Leyi Wei , Ran Su , Qiangguo Jin

Scribble-supervised medical image segmentation tackles the limitation of sparse masks. Conventional approaches alternate between: labeling pseudo-masks and optimizing network parameters. However, such iterative two-stage paradigm is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Zefan Yang , Di Lin , Dong Ni , Yi Wang

The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zihang Liu , Chunhui Zhao

Performance metrics for medical image segmentation models are used to measure the agreement between the reference annotation and the predicted segmentation. Usually, overlap metrics, such as the Dice, are used as a metric to evaluate the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Sophie Ostmeier , Brian Axelrod , Jeroen Bertels , Fabian Isensee , Maarten G. Lansberg , Soren Christensen , Gregory W. Albers , Li-Jia Li , Jeremy J. Heit

Medical image segmentation, the task of partitioning an image into meaningful parts, is an important step toward automating medical image analysis and is at the crux of a variety of medical imaging applications, such as computer aided…

Computer Vision and Pattern Recognition · Computer Science 2016-07-06 Masoud S. Nosrati , Ghassan Hamarneh

Knowing when a trained segmentation model is encountering data that is different to its training data is important. Understanding and mitigating the effects of this play an important part in their application from a performance and…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 David S. W. Williams , Daniele De Martini , Matthew Gadd , Paul Newman

Interactive segmentation uses real-time user inputs, such as mouse clicks, to iteratively refine model predictions. Although not originally designed to address distribution shifts, this paradigm naturally lends itself to such challenges. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Wentian Xu , Ziyun Liang , Harry Anthony , Yasin Ibrahim , Felix Cohen , Guang Yang , Konstantinos Kamnitsas

Robust segmentation is critical for deriving quantitative measures from large-scale, multi-center, and longitudinal medical scans. Manually annotating medical scans, however, is expensive and labor-intensive and may not always be available…

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma