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As zebrafish develop, black and gold stripes form across their skin due to the interactions of brightly colored pigment cells. These characteristic patterns emerge on the growing fish body, as well as on the anal and caudal fins. While…

The Turing patterning mechanism is believed to underly the formation of repetitive structures in development, such as zebrafish stripes and mammalian digits, but it has proved difficult to isolate the specific biochemical species…

Molecular Networks · Quantitative Biology 2018-03-22 Stephen Smith , Neil Dalchau

Complex patterns emerge across a wide range of biological systems. While such patterns often exhibit remarkable robustness, variation and irregularity exist at multiple scales and can carry important information about the underlying agent…

Quantitative Methods · Quantitative Biology 2025-09-16 Nour Khoudari , John Nardini , Alexandria Volkening

Many animals have patterned fur, feathers, or scales, such as the stripes of a zebra. Turing models, or reaction-diffusion systems, are a class of mathematical models of interacting species that have been successfully used to generate…

Biological Physics · Physics 2023-12-04 Michael F. Staddon

We numerically solve the active nematohydrodynamic equations of motion, coupled to a Turing reaction-diffusion model, to study the effect of active nematic flow on the stripe patterns resulting from a Turing instability. If the activity is…

Soft Condensed Matter · Physics 2021-11-04 Saraswat Bhattacharyya , Julia M. Yeomans

In this paper we propose a "discrete in continuous" mathematical model for the morphogenesis of the posterior lateral line system in zebrafishes. Our model follows closely the results obtained in recent biological experiments. We rely on a…

Cell Behavior · Quantitative Biology 2017-05-29 Ezio Di Costanzo , Roberto Natalini , Luigi Preziosi

Reaction diffusion systems with Turing instability and mass conservation are studied. In such systems, abrupt decays of stripes follow quasi-stationary states in sequence. At steady state, the distance between stripes is much longer than…

Pattern Formation and Solitons · Physics 2009-11-11 Shuji Ishihara , Mikiya Otsuji , Atsushi Mochizuki

In this paper, we develop a mean-field model for simulating the microstructure evolution of crystalline materials during static recrystallization. The model considers a population of individual cells (i.e. grains and subgrains) growing in a…

Materials Science · Physics 2020-05-18 Arthur Després , Michael Greenwood , Chad Sinclair

It is common to use a compartmental, fluid model described by a system of ordinary differential equations (ODEs) to model disease spread. In addition to their simplicity, these models are also the mean-field approximations of more accurate…

Probability · Mathematics 2016-04-15 Benjamin Armbruster , Ekkehard Beck

Turing patterns on unbounded domains have been widely studied in systems of reaction-diffusion equations. However, up to now, they have not been studied for systems of conservation laws. Here, we (i) derive conditions for Turing instability…

Analysis of PDEs · Mathematics 2018-01-17 Blake Barker , Soyeun Jung , Kevin Zumbrun

Turing instability in activator-inhibitor systems provides a paradigm of nonequilibrium pattern formation; it has been extensively investigated for biological and chemical processes. Turing pattern formation should furthermore be possible…

Adaptation and Self-Organizing Systems · Physics 2010-05-13 Hiroya Nakao , Alexander S. Mikhailov

We study the mechanisms of pattern formation for vegetation dynamics in water-limited regions. Our analysis is based on a set of two partial differential equations (PDEs) of reaction-diffusion type for the biomass and water and one ordinary…

Dynamical Systems · Mathematics 2023-03-24 Konstantinos Spiliotis , Lucia Russo , Francesco Giannino , Constantinos Siettos

Among living organisms, there are species that change their patterns on their body surface during their growth process and those that maintain their patterns. Theoretically, it has been shown that large-scale species do not form distinct…

Biological Physics · Physics 2025-08-27 Shin Nishihara , Toru Ohira

The aim of this paper is to contribute to the understanding of the pattern formation phenomenon in reaction-diffusion equations coupled with ordinary differential equations. Such systems of equations arise, for example, from modeling of…

Analysis of PDEs · Mathematics 2016-07-15 Anna Marciniak-Czochra , Grzegorz Karch , Kanako Suzuki

Complex contagion models that involve contagion along higher-order structures, such as simplicial complexes and hypergraphs, yield new classes of mean-field models. Interestingly, the differential equations arising from many such models…

Physics and Society · Physics 2025-09-24 István Z. Kiss , Christian Bick , Péter L. Simon

Throughout developmental biology and ecology, transport can be driven by nonlocal interactions. Examples include cells that migrate based on contact with pseudopodia extended from other cells, and animals that move based on their vision of…

Pattern Formation and Solitons · Physics 2023-07-07 Thomas Jun Jewell , Andrew L. Krause , Philip K. Maini , Eamonn A. Gaffney

Collective behaviour in living systems is observed across many scales, from bacteria to insects, to fish shoals. Zebrafish have emerged as a model system amenable to laboratory study. Here we report a three-dimensional study of the…

Statistical Mechanics · Physics 2024-05-16 Yushi Yang , Francesco Turci , Erika Kague , Chrissy L. Hammond , John Russo , C. Patrick Royall

Confirming Turing's theory of morphogens in developmental processes is challenging, and synthetic biology has opened new avenues for testing Turing's predictions. Synthetic mammalian pattern formation has been recently achieved through a…

Pattern Formation and Solitons · Physics 2025-09-22 Mohamed Amine Ouchdiri , Saad Benjelloun , Adnane Saoud , Irene Otero-Muras

Self-organized pattern behavior is ubiquitous throughout nature, from fish schooling to collective cell dynamics during organism development. Qualitatively these patterns display impressive consistency, yet variability inevitably exists…

Quantitative Methods · Quantitative Biology 2022-06-08 Melissa R. McGuirl , Alexandria Volkening , Björn Sandstede

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

Tissues and Organs · Quantitative Biology 2019-02-14 Melinda Liu Perkins , Murat Arcak
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