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In dealing with constrained multi-objective optimization problems (CMOPs), a key issue of multi-objective evolutionary algorithms (MOEAs) is to balance the convergence and diversity of working populations.

Neural and Evolutionary Computing · Computer Science 2019-06-04 Zhun Fan , Zhaojun Wang , Wenji Li , Yutong Yuan , Yugen You , Zhi Yang , Fuzan Sun , Jie Ruan , Zhaocheng Li

The Internet of Bio-nano Things is a significant development for next generation communication technologies. Because conventional wireless communication technologies face challenges in realizing new applications (e.g., in-body area networks…

Information Theory · Computer Science 2021-07-06 Bon-Hong Koo , Changmin Lee , Ali E. Pusane , Tuna Tugcu , Chan-Byoung Chae

Designing molecules with optimized properties remains a fundamental challenge due to the intricate relationship between molecular structure and properties. Traditional computational approaches that address the combinatorial number of…

Quantum Physics · Physics 2025-08-25 Francesco Calcagno , Delmar G. A. Cabral , Ivan Rivalta , Victor S. Batista

It is widely recognized in modern machine learning practice that access to a diverse set of tasks can enhance performance across those tasks. This observation suggests that, unlike in general multi-objective optimization, the objectives in…

Machine Learning · Computer Science 2025-09-09 Ben Kretzu , Karen Ullrich , Yonathan Efroni

This research concerns a type of configuration optimization problems frequently encountered in engineering design and manufacturing, where the envelope volume in space occupied by a number of components needs to be minimized along with…

Computational Engineering, Finance, and Science · Computer Science 2017-06-13 Pei Cao , Zhaoyan Fan , Robert X. Gao , Jiong Tang

A novel multiscale consensus-based optimization (CBO) algorithm for solving bi- and tri-level optimization problems is introduced. Existing CBO techniques are generalized by the proposed method through the employment of multiple interacting…

Optimization and Control · Mathematics 2025-06-23 Michael Herty , Yuyang Huang , Dante Kalise , Hicham Kouhkouh

Combinatorial optimization is a promising area for achieving quantum speedup. Quantum approximate optimization algorithm (QAOA) is designed to search for low-energy states of the Ising model, which correspond to near-optimal solutions of…

Quantum Physics · Physics 2025-10-14 Tatsuhiko Shirai , Nozomu Togawa

Inspired by recent developments in various areas of science relevant to quantum computing, we introduce quantum manifold optimization (QMO) as a promising framework for solving constrained optimization problems in next-generation wireless…

Signal Processing · Electrical Eng. & Systems 2025-04-15 Getuar Rexhepi , Hyeon Seok Rou , Giuseppe Thadeu Freitas de Abreu

Many crucial scientific problems involve designing novel molecules with desired properties, which can be formulated as a black-box optimization problem over the discrete chemical space. In practice, multiple conflicting objectives and…

Machine Learning · Computer Science 2023-11-03 Yiheng Zhu , Jialu Wu , Chaowen Hu , Jiahuan Yan , Chang-Yu Hsieh , Tingjun Hou , Jian Wu

Optimizing the structure of molecules to achieve desired properties is a central bottleneck across the chemical sciences, particularly in the pharmaceutical industry where it underlies the discovery of new drugs. Since molecular property…

Artificial Intelligence · Computer Science 2026-02-19 Fabian P. Krüger , Andrea Hunklinger , Adrian Wolny , Tim J. Adler , Igor Tetko , Santiago David Villalba

Choosing decision variables deterministically (deterministic decision-making) can be regarded as a particular case of choosing decision variables probabilistically (probabilistic decision-making). It is necessary to investigate whether…

Optimization and Control · Mathematics 2023-09-18 Xun Shen , Yuhu Wu , Satoshi Ito , Jun-ichi Imura

Optimization of materials performance for specific applications often requires balancing multiple aspects of materials functionality. Even for the cases where generative physical model of material behavior is known and reliable, this often…

Materials Science · Physics 2021-12-15 Arpan Biswas , Anna N. Morozovska , Maxim Ziatdinov , Eugene A. Eliseev , Sergei V. Kalinin

Optimization strategies driven by machine learning, such as Bayesian optimization, are being explored across experimental sciences as an efficient alternative to traditional design of experiment. When combined with automated laboratory…

Optimization and Control · Mathematics 2022-10-18 Riley J. Hickman , Matteo Aldeghi , Florian Häse , Alán Aspuru-Guzik

The discovery of therapeutic molecules is fundamentally a multi-objective optimization problem. One formulation of the problem is to identify molecules that simultaneously exhibit strong binding affinity for a target protein, minimal…

Quantitative Methods · Quantitative Biology 2023-10-17 Jenna C. Fromer , David E. Graff , Connor W. Coley

The accuracy of molecular simulations is fundamentally limited by the interatomic potentials that govern atomic interactions. Traditional potential development, which relies heavily on ab initio calculations, frequently struggles to…

Disordered Systems and Neural Networks · Physics 2025-10-16 Ruoxia Chen , Kai Yang , Morten M. Smedskjaer , N. M. Anoop Krishnan , Jaime Marian , Fabian Rosner

Software configuration tuning is essential for optimizing a given performance objective (e.g., minimizing latency). Yet, due to the software's intrinsically complex configuration landscape and expensive measurement, there has been a rather…

Software Engineering · Computer Science 2024-03-18 Pengzhou Chen , Tao Chen , Miqing Li

A global optimization framework, acronymed COMBEO (Change OfMeasure Based Evolutionary Optimization), is proposed. An important aspect in the development is a set of derivative-free additive directional terms obtainable through a change of…

Methodology · Statistics 2014-11-10 Saikat Sarkar , Debasish Roy

We consider the problem of constrained multi-objective (MO) blackbox optimization using expensive function evaluations, where the goal is to approximate the true Pareto set of solutions satisfying a set of constraints while minimizing the…

Machine Learning · Computer Science 2020-09-02 Syrine Belakaria , Aryan Deshwal , Janardhan Rao Doppa

Multi-fidelity Bayesian Optimization (MFBO) is a promising framework to speed up materials and molecular discovery as sources of information of different accuracies are at hand at increasing cost. Despite its potential use in chemical…

Realizing high-throughput aberration-corrected Scanning Transmission Electron Microscopy (STEM) exploration of atomic structures requires rapid tuning of multipole probe correctors while compensating for the inevitable drift of the optical…

Machine Learning · Computer Science 2026-01-28 Utkarsh Pratiush , Austin Houston , Richard Liu , Gerd Duscher , Sergei Kalinin