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Tracking many cells in time-lapse 3D image sequences is an important challenging task of bioimage informatics. Motivated by a study of brain-wide 4D imaging of neural activity in C. elegans, we present a new method of multi-cell tracking.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Osamu Hirose , Shotaro Kawaguchi , Terumasa Tokunaga , Yu Toyoshima , Takayuki Teramoto , Sayuri Kuge , Takeshi Ishihara , Yuichi Iino , Ryo Yoshida

We present a novel end-to-end approach to keypoint detection and tracking in an event stream that provides better precision and much longer keypoint tracks than previous methods. This is made possible by two contributions working together.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Philippe Chiberre , Etienne Perot , Amos Sironi , Vincent Lepetit

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Filip Lux , Petr Matula

With the advance of experimental techniques such as time-lapse fluorescence microscopy, the availability of single-cell trajectory data has vastly increased, and so has the demand for computational methods suitable for parameter inference…

Quantitative Methods · Quantitative Biology 2016-07-06 Irena Kuzmanovska , Andreas Milias-Argeitis , Christoph Zechner , Mustafa Khammash

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

We present Patherea, a unified framework for point-based cell detection and classification that enables the development and fair evaluation of state-of-the-art methods. To support this, we introduce a large-scale dataset that replicates the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Dejan Štepec , Maja Jerše , Snežana Đokić , Jera Jeruc , Nina Zidar , Danijel Skočaj

Supervised neural approaches are hindered by their dependence on large, meticulously annotated datasets, a requirement that is particularly cumbersome for sequential tasks. The quality of annotations tends to deteriorate with the transition…

Tracking-Any-Point (TAP) models aim to track any point through a video which is a crucial task in AR/XR and robotics applications. The recently introduced TAPNext approach proposes an end-to-end, recurrent transformer architecture to track…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Sebastian Jung , Artem Zholus , Martin Sundermeyer , Carl Doersch , Ross Goroshin , David Joseph Tan , Sarath Chandar , Rudolph Triebel , Federico Tombari

Recent years have seen a rapid growth in new approaches improving the accuracy of semantic segmentation in a weakly supervised setting, i.e. with only image-level labels available for training. However, this has come at the cost of…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Nikita Araslanov , Stefan Roth

Weakly supervised semantic segmentation is a challenging task as it only takes image-level information as supervision for training but produces pixel-level predictions for testing. To address such a challenging task, most recent…

Computer Vision and Pattern Recognition · Computer Science 2019-11-20 Bingfeng Zhang , Jimin Xiao , Yunchao Wei , Mingjie Sun , Kaizhu Huang

Segmenting video content into events provides semantic structures for indexing, retrieval, and summarization. Since motion cues are not available in continuous photo-streams, and annotations in lifelogging are scarce and costly, the frames…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Ana Garcia del Molino , Joo-Hwee Lim , Ah-Hwee Tan

Recently, single-stage embedding based deep learning algorithms gain increasing attention in cell segmentation and tracking. Compared with the traditional "segment-then-associate" two-stage approach, a single-stage algorithm not only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-21 Mengyang Zhao , Aadarsh Jha , Quan Liu , Bryan A. Millis , Anita Mahadevan-Jansen , Le Lu , Bennett A. Landman , Matthew J. Tyskac , Yuankai Huo

A major obstacle in instance segmentation is that existing methods often need many per-pixel labels in order to be effective. These labels require large human effort and for certain applications, such labels are not readily available. To…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Issam H. Laradji , David Vazquez , Mark Schmidt

Tracking any point (TAP) is a fundamental yet challenging task in computer vision, requiring high precision and long-term motion reasoning. Recent attempts to combine RGB frames and event streams have shown promise, yet they typically rely…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Jiaxiong Liu , Zhen Tan , Jinpu Zhang , Yi Zhou , Hui Shen , Xieyuanli Chen , Dewen Hu

U-Net and its variants have been demonstrated to work sufficiently well in biological cell tracking and segmentation. However, these methods still suffer in the presence of complex processes such as collision of cells, mitosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Deepak K. Gupta , Nathan de Bruijn , Andreas Panteli , Efstratios Gavves

We study the problem of detecting change points (CPs) that are characterized by a subset of dimensions in a multi-dimensional sequence. A method for detecting those CPs can be formulated as a two-stage method: one for selecting relevant…

Machine Learning · Statistics 2018-03-05 Yuta Umezu , Ichiro Takeuchi

We present a new method for efficient high-quality image segmentation of objects and scenes. By analogizing classical computer graphics methods for efficient rendering with over- and undersampling challenges faced in pixel labeling tasks,…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Alexander Kirillov , Yuxin Wu , Kaiming He , Ross Girshick

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr