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Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

CNN visualization and interpretation methods, like class-activation maps (CAMs), are typically used to highlight the image regions linked to class predictions. These models allow to simultaneously classify images and extract class-dependent…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Soufiane Belharbi , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Infectious keratitis is the most common entities of corneal diseases, in which pathogen grows in the cornea leading to inflammation and destruction of the corneal tissues. Infectious keratitis is a medical emergency, for which a rapid and…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yesheng Xu , Ming Kong , Wenjia Xie , Runping Duan , Zhengqing Fang , Yuxiao Lin , Qiang Zhu , Siliang Tang , Fei Wu , Yu-Feng Yao

The demand for accurate food quantification has increased in the recent years, driven by the needs of applications in dietary monitoring. At the same time, computer vision approaches have exhibited great potential in automating tasks within…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Valasia Vlachopoulou , Ioannis Sarafis , Alexandros Papadopoulos

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

In this paper, we present the first attempt to estimate the necessity of debulking coronary artery calcifications from computed tomography (CT) images. We formulate this task as a Multiple-instance Learning (MIL) problem. The difficulty of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Kaito Shiku , Ichika Seo , Tetsuya Matoba , Rissei Hino , Yasuhiro Nakano , Ryoma Bise

Medical images are generally labeled by multiple experts before the final ground-truth labels are determined. Consensus or disagreement among experts regarding individual images reflects the gradeability and difficulty levels of the image.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Shuang Yu , Hong-Yu Zhou , Kai Ma , Cheng Bian , Chunyan Chu , Hanruo Liu , Yefeng Zheng

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

While deep learning methods have shown great success in medical image analysis, they require a number of medical images to train. Due to data privacy concerns and unavailability of medical annotators, it is oftentimes very difficult to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Yue Yang , Pengtao Xie

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

The current COVID-19 pandemic overloads healthcare systems, including radiology departments. Though several deep learning approaches were developed to assist in CT analysis, nobody considered study triage directly as a computer science…

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Chronic pain is a global health challenge affecting millions of individuals, making it essential for physicians to have reliable and objective methods to measure the functional impact of clinical treatments. Traditionally used methods, like…

Machine Learning · Computer Science 2026-03-23 Yuanheng Mao , Lillian Yang , Stephen Yang , Ethan Shao , Zihan Li

Chronic obstructive pulmonary disease (COPD) is a lung disease which can be quantified using chest computed tomography (CT) scans. Recent studies have shown that COPD can be automatically diagnosed using weakly supervised learning of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Veronika Cheplygina , Isabel Pino Peña , Jesper Holst Pedersen , David A. Lynch , Lauge Sørensen , Marleen de Bruijne

In this paper, we address the Multi-Instance-Learning (MIL) problem when bag labels are naturally represented as ordinal variables (Multi--Instance--Ordinal Regression). Moreover, we consider the case where bags are temporal sequences of…

Computer Vision and Pattern Recognition · Computer Science 2016-09-07 Adria Ruiz , Ognjen Rudovic , Xavier Binefa , Maja Pantic

Under the global pandemic of COVID-19, building an automated framework that quantifies the severity of COVID-19 and localizes the relevant lesion on chest X-ray images has become increasingly important. Although pixel-level lesion severity…

Image and Video Processing · Electrical Eng. & Systems 2021-03-15 Gwanghyun Kim , Sangjoon Park , Yujin Oh , Joon Beom Seo , Sang Min Lee , Jin Hwan Kim , Sungjun Moon , Jae-Kwang Lim , Jong Chul Ye

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

During the diagnostic process, clinicians leverage multimodal information, such as chief complaints, medical images, and laboratory-test results. Deep-learning models for aiding diagnosis have yet to meet this requirement. Here we report a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Hong-Yu Zhou , Yizhou Yu , Chengdi Wang , Shu Zhang , Yuanxu Gao , Jia Pan , Jun Shao , Guangming Lu , Kang Zhang , Weimin Li

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

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