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Multi-centre colonoscopy images from various medical centres exhibit distinct complicating factors and overlays that impact the image content, contingent on the specific acquisition centre. Existing Deep Segmentation networks struggle to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Valentina Corbetta , Regina Beets-Tan , Wilson Silva

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Objective: Ulcerative colitis (UC), characterized by chronic inflammation with alternating remission-relapse cycles, requires precise histological healing (HH) evaluation to improve clinical outcomes. To overcome the limitations of…

Quantitative Methods · Quantitative Biology 2025-05-16 Zhengxuan Qiu , Bo Peng , Xiaoying Tang , Jiankun Wang , Qin Guo

Inflammatory bowel disease (IBD), in particular ulcerative colitis (UC), is graded by endoscopists and this assessment is the basis for risk stratification and therapy monitoring. Presently, endoscopic characterisation is largely operator…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ziang Xu , Sharib Ali , Soumya Gupta , Simon Leedham , James E East , Jens Rittscher

How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Zekun Li , Wei Zhao , Feng Shi , Lei Qi , Xingzhi Xie , Ying Wei , Zhongxiang Ding , Yang Gao , Shangjie Wu , Jun Liu , Yinghuan Shi , Dinggang Shen

Computed Tomography (CT) scans provide a detailed image of the lungs, allowing clinicians to observe the extent of damage caused by COVID-19. The CT severity score (CTSS) based scoring method is used to identify the extent of lung…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Anand Thyagachandran , Hema A Murthy

In this paper, we propose a novel selection strategy for contrastive learning for medical images. On natural images, contrastive learning uses augmentations to select positive and negative pairs for the contrastive loss. However, in the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Kiran Kokilepersaud , Mohit Prabhushankar , Ghassan AlRegib , Stephanie Trejo Corona , Charles Wykoff

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Phenotyping is the process of distinguishing groups of patients to identify different types of disease progression. A recent trend employs low-rank matrix and tensor factorization methods for their capability of dealing with multi-modal,…

Machine Learning · Computer Science 2025-06-26 Cristian Minoccheri , Sophia Tesic , Kayvan Najarian , Ryan Stidham

Wound classification is an essential step of wound diagnosis. An efficient classifier can assist wound specialists in classifying wound types with less financial and time costs and help them decide an optimal treatment procedure. This study…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 D. M. Anisuzzaman , Yash Patel , Behrouz Rostami , Jeffrey Niezgoda , Sandeep Gopalakrishnan , Zeyun Yu

Interpretability is a critical factor in applying complex deep learning models to advance the understanding of brain disorders in neuroimaging studies. To interpret the decision process of a trained classifier, existing techniques typically…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Zixuan Liu , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

Effective recognition of acute and difficult-to-heal wounds is a necessary step in wound diagnosis. An efficient classification model can help wound specialists classify wound types with less financial and time costs and also help in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ramin Mousa , Hadis Taherinia , Khabiba Abdiyeva , Amir Ali Bengari , Mohammadmahdi Vahediahmar

Multiple instance learning (MIL) is a supervised learning methodology that aims to allow models to learn instance class labels from bag class labels, where a bag is defined to contain multiple instances. MIL is gaining traction for learning…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Samuel W. Remedios , Zihao Wu , Camilo Bermudez , Cailey I. Kerley , Snehashis Roy , Mayur B. Patel , John A. Butman , Bennett A. Landman , Dzung L. Pham

Data-driven methods have shown tremendous progress in medical image analysis. In this context, deep learning-based supervised methods are widely popular. However, they require a large amount of training data and face issues in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Ziang Xu , Jens Rittscher , Sharib Ali

Endoscopy is a valuable tool for the early diagnosis of colon cancer. However, it requires the expertise of endoscopists and is a time-consuming process. In this work, we propose a new multi-label classification method, which considers two…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Zahra Sobhaninia , Nasrin Abharian , Nader Karimi , Shahram Shirani , Shadrokh Samavi

We propose a method to predict severity of age related macular degeneration (AMD) from input optical coherence tomography (OCT) images. Although there is no standard clinical severity scale for AMD, we leverage deep learning (DL) based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-09 Dwarikanath Mahapatra

The unique nature of histopathology images opens the door to domain-specific formulations of image translation models. We propose a difficulty translation model that modifies colorectal histopathology images to be more challenging to…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Jerry Wei , Arief Suriawinata , Xiaoying Liu , Bing Ren , Mustafa Nasir-Moin , Naofumi Tomita , Jason Wei , Saeed Hassanpour