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Representational similarity metrics are fundamental tools in neuroscience and AI, yet we lack systematic comparisons of their discriminative power across model families. We introduce a quantitative framework to evaluate representational…

Machine Learning · Computer Science 2025-12-10 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

The extent to which different biological and artificial neural systems rely on equivalent internal representations to support similar tasks remains a central question in neuroscience and machine learning. Prior work typically compares…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

Neural responses encode information that is useful for a variety of downstream tasks. A common approach to understand these systems is to build regression models or ``decoders'' that reconstruct features of the stimulus from neural…

Machine Learning · Statistics 2024-11-14 Sarah E. Harvey , David Lipshutz , Alex H. Williams

How do we know if two systems - biological or artificial - process information in a similar way? Similarity measures such as linear regression, Centered Kernel Alignment (CKA), Normalized Bures Similarity (NBS), and angular Procrustes…

Neurons and Cognition · Quantitative Biology 2024-12-31 Nathan Cloos , Moufan Li , Markus Siegel , Scott L. Brincat , Earl K. Miller , Guangyu Robert Yang , Christopher J. Cueva

Measuring similarity of neural networks to understand and improve their behavior has become an issue of great importance and research interest. In this survey, we provide a comprehensive overview of two complementary perspectives of…

Machine Learning · Computer Science 2025-05-22 Max Klabunde , Tobias Schumacher , Markus Strohmaier , Florian Lemmerich

Recent work has sought to understand the behavior of neural networks by comparing representations between layers and between different trained models. We examine methods for comparing neural network representations based on canonical…

Machine Learning · Computer Science 2019-07-22 Simon Kornblith , Mohammad Norouzi , Honglak Lee , Geoffrey Hinton

In both artificial and biological systems, the centered kernel alignment (CKA) has become a widely used tool for quantifying neural representation similarity. While current CKA estimators typically correct for the effects of finite stimuli…

Neurons and Cognition · Quantitative Biology 2025-02-26 Chanwoo Chun , Abdulkadir Canatar , SueYeon Chung , Daniel D. Lee

In recent years, various methods and benchmarks have been proposed to empirically evaluate the alignment of artificial neural networks to human neural and behavioral data. But how aligned are different alignment metrics? To answer this…

Neurons and Cognition · Quantitative Biology 2024-07-11 Jannis Ahlert , Thomas Klein , Felix Wichmann , Robert Geirhos

As we consider entrusting Large Language Models (LLMs) with key societal and decision-making roles, measuring their alignment with human cognition becomes critical. This requires methods that can assess how these systems represent…

Artificial Intelligence · Computer Science 2025-10-03 Mattson Ogg , Ritwik Bose , Jamie Scharf , Christopher Ratto , Michael Wolmetz

Given that AI systems are set to play a pivotal role in future decision-making processes, their trustworthiness and reliability are of critical concern. Due to their scale and complexity, modern AI systems resist direct interpretation, and…

Artificial Intelligence · Computer Science 2025-01-03 Binxia Xu , Antonis Bikakis , Daniel Onah , Andreas Vlachidis , Luke Dickens

Comparing learned neural representations in neural networks is a challenging but important problem, which has been approached in different ways. The Centered Kernel Alignment (CKA) similarity metric, particularly its linear variant, has…

Machine Learning · Computer Science 2022-11-17 MohammadReza Davari , Stefan Horoi , Amine Natik , Guillaume Lajoie , Guy Wolf , Eugene Belilovsky

Centred Kernel Alignment (CKA) has recently emerged as a popular metric to compare activations from biological and artificial neural networks (ANNs) in order to quantify the alignment between internal representations derived from stimuli…

Neurons and Cognition · Quantitative Biology 2024-05-03 Alex Murphy , Joel Zylberberg , Alona Fyshe

Biological and artificial information processing systems form representations of the world that they can use to categorize, reason, plan, navigate, and make decisions. How can we measure the similarity between the representations formed by…

Neuroscientists and computer vision researchers use model-brain alignment benchmarks to compare artificial and biological vision systems. These benchmarks rank models according to alignment measures such as the similarity of…

Neurons and Cognition · Quantitative Biology 2026-04-24 Larissa Höfling , Matthias Tangemann , Lotta Piefke , Susanne Keller , Katrin Franke , Matthias Bethge

Activation-alignment measures such as Representational Similarity Analysis (RSA), Canonical Correlation Analysis (CCA), and Centered Kernel Alignment (CKA) are widely used to compare biological and artificial neural representations. Recent…

Machine Learning · Computer Science 2026-05-08 Amirhossein Yavari , Farnaz Zamani Esfahlani

Determining the similarities and differences between humans and artificial intelligence (AI) is an important goal both in computational cognitive neuroscience and machine learning, promising a deeper understanding of human cognition and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Florian P. Mahner , Lukas Muttenthaler , Umut Güçlü , Martin N. Hebart

Decoding approaches are widely used in neuroscience and machine learning to compare stimulus representations across neural systems, such as different brain regions, organisms, and deep learning models. Popular methods include decoding…

Neurons and Cognition · Quantitative Biology 2026-05-08 Johannes Bertram , Luciano Dyballa , T. Anderson Keller , Savik Kinger , Steven W. Zucker

Similarity metrics such as representational similarity analysis (RSA) and centered kernel alignment (CKA) have been used to compare layer-wise representations between neural networks. However, these metrics are confounded by the population…

Machine Learning · Statistics 2022-02-02 Tianyu Cui , Yogesh Kumar , Pekka Marttinen , Samuel Kaski

Which neural networks are similar is a fundamental question for both machine learning and neuroscience. Here, it is proposed to base comparisons on the predictive distributions of linear readouts from intermediate representations. In…

Machine Learning · Computer Science 2025-05-27 Heiko H. Schütt

Quantifying similarity between neural representations -- e.g. hidden layer activation vectors -- is a perennial problem in deep learning and neuroscience research. Existing methods compare deterministic responses (e.g. artificial networks…

Machine Learning · Computer Science 2023-02-07 Lyndon R. Duong , Jingyang Zhou , Josue Nassar , Jules Berman , Jeroen Olieslagers , Alex H. Williams
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