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Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Doctor-patient consultations require multi-turn, context-aware communication tailored to diverse patient personas. Training or evaluating doctor LLMs in such settings requires realistic patient interaction systems. However, existing…

Artificial Intelligence · Computer Science 2025-10-30 Daeun Kyung , Hyunseung Chung , Seongsu Bae , Jiho Kim , Jae Ho Sohn , Taerim Kim , Soo Kyung Kim , Edward Choi

Mental illness remains one of the most critical public health issues. Despite its importance, many mental health professionals highlight a disconnect between their training and actual real-world patient practice. To help bridge this gap, we…

The simulation of realistic clinical interactions plays a pivotal role in advancing clinical Large Language Models (LLMs) and supporting medical diagnostic education. Existing approaches and benchmarks rely on generic or LLM-generated…

Computation and Language · Computer Science 2026-01-19 Shijie Jiang , Zefan Zhang , Kehua Zhu , Tian Bai , Ruihong Zhao

We develop Polaris, the first safety-focused LLM constellation for real-time patient-AI healthcare conversations. Unlike prior LLM works in healthcare focusing on tasks like question answering, our work specifically focuses on long…

This paper explores the application of large language models (LLMs) in nursing and elderly care, focusing on AI-driven patient monitoring and interaction. We introduce a novel Chinese nursing dataset and implement incremental pre-training…

Computation and Language · Computer Science 2024-12-16 Qiao Sun , Jiexin Xie , Nanyang Ye , Qinying Gu , Shijie Guo

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

In this study, we aimed to determine if fine-tuned large language models (LLMs) can generate accurate, personalized impressions for whole-body PET reports. Twelve language models were trained on a corpus of PET reports using the…

Peer-run organizations (PROs) provide critical, recovery-based behavioral health support rooted in lived experience. As large language models (LLMs) enter this domain, their scale, conversationality, and opacity introduce new challenges for…

Human-Computer Interaction · Computer Science 2026-02-10 Cindy Peng , Megan Chai , Gao Mo , Naveen Raman , Ningjing Tang , Shannon Pagdon , Margaret Swarbrick , Nev Jones , Fei Fang , Hong Shen

LLM-based client simulation has emerged as a promising tool for training novice counselors and evaluating automated counseling systems. However, existing client simulation approaches face three key challenges: (1) limited diversity and…

Computation and Language · Computer Science 2026-01-13 Huachuan Qiu , Zhaoming Chen , Yuqian Chen , Yuan Xie , Yu Lu , Zhenzhong Lan

Effective patient communication is pivotal in healthcare, yet traditional medical training often lacks exposure to diverse, challenging interpersonal dynamics. To bridge this gap, this study proposes the use of Large Language Models (LLMs)…

The exponential growth of social media and generative AI has transformed information dissemination, fostering connectivity but also accelerating the spread of misinformation. Understanding information propagation dynamics and developing…

Artificial Intelligence · Computer Science 2025-07-09 Litian Zhang , Xiaoming Zhang , Bingyu Yan , Ziyi Zhou , Bo Zhang , Zhenyu Guan , Xi Zhang , Chaozhuo Li

A common approach to personalization in large language models (LLMs) is to incorporate a subset of the user memory into the prompt at inference time to guide the model's generation. Existing methods select these subsets primarily using…

Artificial Intelligence · Computer Science 2026-04-17 Jillian Fisher , Jennifer Neville , Chan Young Park

Mental health is a growing global concern, prompting interest in AI-driven solutions to expand access to psychosocial support. \emph{Peer support}, grounded in lived experience, offers a valuable complement to professional care. However,…

Human-Computer Interaction · Computer Science 2026-04-10 Kellie Yu Hui Sim , Roy Ka-Wei Lee , Kenny Tsu Wei Choo

Effective communication training is essential to preparing nurses for high-quality patient care. While standardized patient (SP) simulations provide valuable experiential learning, they are often costly and inflexible. Virtual patient (VP)…

Computation and Language · Computer Science 2025-06-03 Keyeun Lee , Seolhee Lee , Esther Hehsun Kim , Yena Ko , Jinsu Eun , Dahee Kim , Hyewon Cho , Haiyi Zhu , Robert E. Kraut , Eunyoung Suh , Eun-mee Kim , Hajin Lim

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Large language models (LLMs) are rapidly being adopted for tasks like drafting emails, summarizing meetings, and answering health questions. In these settings, users may need to share private information (e.g., contact details, health…

Computation and Language · Computer Science 2026-01-16 Xiaoyuan Wu , Roshni Kaushik , Wenkai Li , Lujo Bauer , Koichi Onoue

Post-discharge care management coordinates patients' referrals to improve their health after being discharged from hospitals, especially elderly and chronically ill patients. In a care management setting, health referrals are processed by a…

Machine Learning · Computer Science 2022-06-28 Mohammed Mahyoub

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

Large Language Models (LLMs) have demonstrated remarkable proficiency in human interactions, yet their application within the medical field remains insufficiently explored. Previous works mainly focus on the performance of medical knowledge…

Computation and Language · Computer Science 2024-07-23 Yusheng Liao , Yutong Meng , Yuhao Wang , Hongcheng Liu , Yanfeng Wang , Yu Wang
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