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Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Object detection when provided image-level labels instead of instance-level labels (i.e., bounding boxes) during training is an important problem in computer vision, since large scale image datasets with instance-level labels are extremely…

Computer Vision and Pattern Recognition · Computer Science 2017-03-01 Ziang Yan , Jian Liang , Weishen Pan , Jin Li , Changshui Zhang

Since the rise of deep learning, many computer vision tasks have seen significant advancements. However, the downside of deep learning is that it is very data-hungry. Especially for segmentation problems, training a deep neural net requires…

Computer Vision and Pattern Recognition · Computer Science 2021-10-13 Robby Neven , Davy Neven , Bert De Brabandere , Marc Proesmans , Toon Goedemé

Lesion segmentation on nasal endoscopic images is challenging due to its complex lesion features. Fully-supervised deep learning methods achieve promising performance with pixel-level annotations but impose a significant annotation burden…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Pengyu Jie , Wanquan Liu , Chenqiang Gao , Yihui Wen , Rui He , Weiping Wen , Pengcheng Li , Jintao Zhang , Deyu Meng

Deep segmentation neural networks require large training datasets with pixel-wise segmentations, which are expensive to obtain in practice. Mixed supervision could mitigate this difficulty, with a small fraction of the data containing…

Computer Vision and Pattern Recognition · Computer Science 2020-12-16 Jose Dolz , Christian Desrosiers , Ismail Ben Ayed

Despite achieving promising results in a breadth of medical image segmentation tasks, deep neural networks require large training datasets with pixel-wise annotations. Obtaining these curated datasets is a cumbersome process which limits…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bingyuan Liu , Christian Desrosiers , Ismail Ben Ayed , Jose Dolz

Human skin segmentation is a crucial task in computer vision and biometric systems, yet it poses several challenges such as variability in skin color, pose, and illumination. This paper presents a robust data-driven skin segmentation method…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Kooshan Hashemifard , Pau Climent-Perez , Francisco Florez-Revuelta

We present a weak to strong generalization methodology for fully automated training of a multi-head extension of the Mask-RCNN method with efficient channel attention for reliable segmentation of overlapping cell nuclei in multiplex cyclic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Lin Bai , Xiaoyang Li , Liqiang Huang , Quynh Nguyen , Hien Van Nguyen , Saurabh Prasad , Dragan Maric , John Redell , Pramod Dash , Badrinath Roysam

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Understanding sleep and activity patterns plays a crucial role in physical and mental health. This study introduces a novel approach for sleep detection using weakly supervised learning for scenarios where reliable ground truth labels are…

Machine Learning · Computer Science 2024-07-09 Matthias Boeker , Vajira Thambawita , Michael Riegler , Pål Halvorsen , Hugo L. Hammer

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

Image and Video Processing · Electrical Eng. & Systems 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

We introduce the problem of weakly supervised Multi-Object Tracking and Segmentation, i.e. joint weakly supervised instance segmentation and multi-object tracking, in which we do not provide any kind of mask annotation. To address it, we…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Idoia Ruiz , Lorenzo Porzi , Samuel Rota Bulò , Peter Kontschieder , Joan Serrat

Accurate segmentation of organelle instances from electron microscopy (EM) images plays an essential role in many neuroscience researches. However, practical scenarios usually suffer from high annotation costs, label scarcity, and large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Dafei Qiu , Shan Xiong , Jiajin Yi , Jialin Peng

The task of parsing subcutaneous vessels in clinical images is often hindered by the high cost and limited availability of ground truth data, as well as the challenge of low contrast and noisy vessel appearances across different patients…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Ayaan Nooruddin Siddiqui , Mahnoor Zaidi , Ayesha Nazneen Shahbaz , Priyadarshini Chatterjee , Krishnan Menon Iyer

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

The detection and segmentation of white blood cells in blood smear images is a key step in medical diagnostics, supporting various downstream tasks such as automated blood cell counting, morphological analysis, cell classification, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Michael Deutges , Chen Yang , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

We consider the task of learning a classifier for semantic segmentation using weak supervision in the form of image labels which specify the object classes present in the image. Our method uses deep convolutional neural networks (CNNs) and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Qinbin Hou , Puneet Kumar Dokania , Daniela Massiceti , Yunchao Wei , Ming-Ming Cheng , Philip Torr

Deep neural networks currently deliver promising results for microscopy image cell segmentation, but they require large-scale labelled databases, which is a costly and time-consuming process. In this work, we relax the labelling requirement…

Computer Vision and Pattern Recognition · Computer Science 2022-08-04 Youssef Dawoud , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis