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To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

Machine Learning · Computer Science 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…

Biological Physics · Physics 2025-02-18 Shobhit Das , Shilpi Pandey , Oliver Hayden

The analysis and design of advection-diffusion based molecular communication (MC) systems in cylindrical environments is of particular interest for applications such as micro-fluidics and targeted drug delivery in blood vessels. Therefore,…

Emerging Technologies · Computer Science 2020-07-06 Maximilian Schäfer , Wayan Wicke , Lukas Brand , Rudolf Rabenstein , Robert Schober

Molecular communication (MC) is an emerging paradigm that enables data transmission through biochemical signals rather than traditional electromagnetic waves. This approach is particularly promising for environments where conventional…

Information Theory · Computer Science 2025-03-17 Vida Gholamiyan , Yaning Zhao , Wafa Labidi , Holger Boche , Christian Deppe

Molecular communication (MC) is an emerging paradigm that takes inspiration from biological processes, enabling communication at the nanoscale and facilitating the development of the Internet of Bio-Nano Things (IoBNT). Traditional models…

Emerging Technologies · Computer Science 2025-01-22 Shaojie Zhang , Ozgur B. Akan

Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum…

Fluid Dynamics · Physics 2017-05-09 Wei-Tao Wu , Nadine Aubry , James F. Antaki , Mehrdad Massoudi

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various…

Emerging Technologies · Computer Science 2022-12-23 Sasitharan Balasubramaniam , Samitha Somathilaka , Sehee Sun , Adrian Ratwatte , Massimiliano Pierobon

In-body communication is an upcoming field with significant implications for medical diagnostics and therapeutic interventions. Microbubbles have gained attention due to their distinct physical properties, making them promising candidates…

Signal Processing · Electrical Eng. & Systems 2026-03-23 Annika Tjabben , Lea Bergkemper , Carolin Conrad , Michael Gundall , Hans D. Schotten

This thesis develops a theoretical framework to evaluate the monitoring capability of IoBNT networks. We consider a scenario in which nanosensors passively flow in the bloodstream and detect biomarkers associated with potential diseases,…

Signal Processing · Electrical Eng. & Systems 2026-05-12 Jorge Torres Gómez

Computer-aided detection has been a research area attracting great interest in the past decade. Machine learning algorithms have been utilized extensively for this application as they provide a valuable second opinion to the doctors.…

Diffusive molecular communication (DMC) is one of the most promising approaches for realizing nano-scale communications in biological environments for healthcare applications. In this paper, a DMC system in biological cylindrical…

Information Theory · Computer Science 2018-11-27 Mohammad Zoofaghari , Hamidreza Arjmandi

Molecular communication (MC) within the synaptic cleft is vital for neurotransmitter diffusion, a process critical to cognitive functions. In Alzheimer's Disease (AD), beta-amyloid oligomers (A$\beta$os) disrupt this communication, leading…

Molecular Networks · Quantitative Biology 2024-09-06 Nayereh FallahBagheri , Ozgur B. Akan

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

Molecular communication (MC) engineering is inspired by the use of chemical signals as information carriers in cell biology. The biological nature of chemical signaling makes MC a promising methodology for interdisciplinary applications…

Emerging Technologies · Computer Science 2020-09-02 Dadi Bi , Apostolos Almpanis , Adam Noel , Yansha Deng , Robert Schober

Molecular Communication (MC) is a bio-inspired communication modality that utilizes chemical signals in the form of molecules to exchange information between spatially separated entities. Pulse shaping is an important process in all…

Emerging Technologies · Computer Science 2023-01-16 Maryam Kahvazi Zadeh , Iman Mokari Bolhassan , Murat Kuscu

In molecular communication (MC) systems, the expected number of molecules observed at the receiver over time after the instantaneous release of molecules by the transmitter is referred to as the channel impulse response (CIR). Knowledge of…

Information Theory · Computer Science 2016-11-17 Vahid Jamali , Arman Ahmadzadeh , Christophe Jardin , Heinrich Sticht , Robert Schober

Air-based molecular communication (MC) has the potential to be one of the first MC systems to be deployed in real-world applications, enabled by existing sensor technologies such as metal-oxide semi-conductor (MOS) sensors. However,…

Today, pipeline networks serve as critical infrastructure for transporting materials such as water, gas, and oil. Modern technologies such as the Internet of Things (IoT), sensor nodes, and inspection robots enable efficient pipeline…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Muneer M. Al-Zubi , Mohamed-Slim Alouini
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