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Large numbers of MS/MS peptide spectra generated in proteomics experiments require efficient, sensitive and specific algorithms for peptide identification. In the Open Mass Spectrometry Search Algorithm [OMSSA], specificity is calculated by…

Quantitative Methods · Quantitative Biology 2007-05-23 Lewis Y. Geer , Sanford P. Markey , Jeffrey A. Kowalak , Lukas Wagner , Ming Xu , Dawn M. Maynard , Xiaoyu Yang , Wenyao Shi , Stephen H. Bryant

Automated documentation of programming source code is a challenging task with significant practical and scientific implications for the developer community. We present a large language model (LLM)-based application that developers can use…

Software Engineering · Computer Science 2025-12-17 Sayak Chakrabarty , Souradip Pal

Machine learning research depends on objectively interpretable, comparable, and reproducible algorithm benchmarks. We advocate the use of curated, comprehensive suites of machine learning tasks to standardize the setup, execution, and…

LLM watermarking, which embeds imperceptible yet algorithmically detectable signals in model outputs to identify LLM-generated text, has become crucial in mitigating the potential misuse of large language models. However, the abundance of…

Cryptography and Security · Computer Science 2024-10-29 Leyi Pan , Aiwei Liu , Zhiwei He , Zitian Gao , Xuandong Zhao , Yijian Lu , Binglin Zhou , Shuliang Liu , Xuming Hu , Lijie Wen , Irwin King , Philip S. Yu

Mass spectrometry-based proteomics has become the tool of choice for identifying and quantifying the proteome of an organism. Though recent years have seen a tremendous improvement in instrument performance and the computational tools used,…

In this fast developing world of information, the amount of medical knowledge is rising at an exponential level. The UMLS (Unified Medical Language Systems), is rich knowledge base consisting files and software that provides many health and…

Computers and Society · Computer Science 2016-12-23 Nareena Soomro , Safeeulah Soomro , Zainab Alansari , Suhni Abbasi , Mohammad Riyaz Belgaum , Abdul Baqi Khakwani

We present OpenML and mldata, open science platforms that provides easy access to machine learning data, software and results to encourage further study and application. They go beyond the more traditional repositories for data sets and…

Machine Learning · Computer Science 2014-02-26 Joaquin Vanschoren , Mikio L. Braun , Cheng Soon Ong

Large language models (LLMs) have shown impressive performance on general-purpose tasks, yet adapting them to specific domains remains challenging due to the scarcity of high-quality domain data. Existing data synthesis tools often struggle…

Computation and Language · Computer Science 2025-07-08 Ziyang Miao , Qiyu Sun , Jingyuan Wang , Yuchen Gong , Yaowei Zheng , Shiqi Li , Richong Zhang

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

Scientific workflow systems are increasingly popular for expressing and executing complex data analysis pipelines over large datasets, as they offer reproducibility, dependability, and scalability of analyses by automatic parallelization on…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-09 Mario Sänger , Ninon De Mecquenem , Katarzyna Ewa Lewińska , Vasilis Bountris , Fabian Lehmann , Ulf Leser , Thomas Kosch

Although Raman spectroscopy is widely used for the investigation of biomedical samples and has a high potential for use in clinical applications, it is not common in clinical routines. One of the factors that obstruct the integration of…

Data Analysis, Statistics and Probability · Physics 2022-01-20 Darina Storozhuk , Oleg Ryabchykov , Juergen Popp , Thomas Bocklitz

In the past decade, deep learning (DL) has achieved unprecedented success in numerous fields including computer vision, natural language processing, and healthcare. In particular, DL is experiencing an increasing development in applications…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Liang Zhang , Johann Li , Ping Li , Xiaoyuan Lu , Peiyi Shen , Guangming Zhu , Syed Afaq Shah , Mohammed Bennarmoun , Kun Qian , Björn W. Schuller

NLP Workbench is a web-based platform for text mining that allows non-expert users to obtain semantic understanding of large-scale corpora using state-of-the-art text mining models. The platform is built upon latest pre-trained models and…

Computation and Language · Computer Science 2024-03-06 Peiran Yao , Matej Kosmajac , Abeer Waheed , Kostyantyn Guzhva , Natalie Hervieux , Denilson Barbosa

As data science and machine learning methods are taking on an increasingly important role in the materials research community, there is a need for the development of machine learning software tools that are easy to use (even for nonexperts…

Computational Physics · Physics 2020-06-26 Ryan Jacobs , Tam Mayeshiba , Ben Afflerbach , Luke Miles , Max Williams , Matthew Turner , Raphael Finkel , Dane Morgan

Nowadays, literature review is a necessary task when trying to solve a given problem. However, an exhaustive literature review is very time-consuming in today's vast literature landscape. It can take weeks, even if looking only for…

Artificial Intelligence · Computer Science 2024-05-16 Deniz Kenan Kılıç , Alex Elkjær Vasegaard , Aurélien Desoeuvres , Peter Nielsen

Crystal Toolkit is an open source tool for viewing, analyzing and transforming crystal structures, molecules and other common forms of materials science data in an interactive way. It is intended to help beginners rapidly develop web-based…

Computational analyses of, e.g., genomic, proteomic, or metabolomic data, commonly result in one or more sets of candidate genes, proteins, or enzymes. These sets are often the outcome of clustering algorithms. Subsequently, it has to be…

Genomics · Quantitative Biology 2007-06-26 Robbe Wunschiers , Martin Vellguth

Machine learning (ML) applications become increasingly common in many domains. ML systems to execute these workloads include numerical computing frameworks and libraries, ML algorithm libraries, and specialized systems for deep neural…

MSstatsQC [3] is an open-source software that provides longitudinal system suitability monitoring tools in the form of control charts for proteomic experiments. It includes simultaneous tools for the mean and dispersion of suitability…

Human-Computer Interaction · Computer Science 2020-03-27 Sara Mohammad Taheri , Omkar Terse , Eralp Dogu , Magy Seif El-Nasr , Olga Vitek

OpenML is an online machine learning platform where researchers can easily share data, machine learning tasks and experiments as well as organize them online to work and collaborate more efficiently. In this paper, we present an R package…