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For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

Computation and Language · Computer Science 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

The field of medical diagnosis has undergone a significant transformation with the advent of large language models (LLMs), yet the challenges of interpretability within these models remain largely unaddressed. This study introduces…

Computation and Language · Computer Science 2024-09-17 Junying Chen , Chi Gui , Anningzhe Gao , Ke Ji , Xidong Wang , Xiang Wan , Benyou Wang

Code contains security and functional bugs. The process of identifying and localizing them is difficult and relies on human labor. In this work, we present a novel approach (FLAG) to assist human debuggers. FLAG is based on the lexical…

Cryptography and Security · Computer Science 2023-06-23 Baleegh Ahmad , Benjamin Tan , Ramesh Karri , Hammond Pearce

Matching patients to clinical trial options is critical for identifying novel treatments, especially in oncology. However, manual matching is labor-intensive and error-prone, leading to recruitment delays. Pipelines incorporating large…

Computation and Language · Computer Science 2025-09-25 Braxton A. Morrison , Madhumita Sushil , Jacob S. Young

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.…

The emergence of Large Language Models (LLMs) presents unprecedented opportunities to revolutionize medical contrastive vision-language pre-training. In this paper, we show how LLMs can facilitate large-scale supervised pre-training,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yingtai Li , Haoran Lai , Xiaoqian Zhou , Shuai Ming , Wenxin Ma , Wei Wei , Shaohua Kevin Zhou

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Alzheimer's disease (AD) has become a prevalent neurodegenerative disease worldwide. Traditional diagnosis still relies heavily on medical imaging and clinical assessment by physicians, which is often time-consuming and resource-intensive…

Computation and Language · Computer Science 2026-02-17 Tongze Zhang , Jun-En Ding , Melik Ozolcer , Fang-Ming Hung , Albert Chih-Chieh Yang , Feng Liu , Yi-Rou Ji , Sang Won Bae

Multilingual pre-trained models exhibit zero-shot cross-lingual transfer, where a model fine-tuned on a source language achieves surprisingly good performance on a target language. While studies have attempted to understand transfer, they…

Computation and Language · Computer Science 2022-11-17 Henry Tang , Ameet Deshpande , Karthik Narasimhan

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Long text classification is challenging for Large Language Models (LLMs) due to token limits and high computational costs. This study explores whether a Retrieval Augmented Generation (RAG) approach using only the most relevant text…

We present Clinical Camel, an open large language model (LLM) explicitly tailored for clinical research. Fine-tuned from LLaMA-2 using QLoRA, Clinical Camel achieves state-of-the-art performance across medical benchmarks among openly…

Computation and Language · Computer Science 2023-08-21 Augustin Toma , Patrick R. Lawler , Jimmy Ba , Rahul G. Krishnan , Barry B. Rubin , Bo Wang

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Time series data from the Intensive Care Unit (ICU) provides critical information for patient monitoring. While recent advancements in applying Large Language Models (LLMs) to time series modeling (TSM) have shown great promise, their…

Machine Learning · Computer Science 2026-01-27 Feixiang Zheng , Yu Wu , Cecilia Mascolo , Ting Dang

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang
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