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The dynamics of molecules are governed by rare event transitions between long-lived (metastable) states. To explore these transitions efficiently, many enhanced sampling protocols have been introduced that involve using simulations with…

Chemical Physics · Physics 2022-09-30 Maaike M. Galama , Hao Wu , Andreas Krämer , Mohsen Sadeghi , Frank Noé

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

We study the parameter estimation method for linear regression models with possibly skewed stable distributed errors. Our estimation procedure consists of two stages: first, for the regression coefficients, the Cauchy quasi-maximum…

Statistics Theory · Mathematics 2025-06-25 Eitaro Kawamo , Hiroki Masuda

Accurate detection of signal components is a frequently-encountered challenge in statistical applications with low signal-to-noise ratio. This problem is particularly challenging in settings with heteroscedastic noise. In certain…

Computation · Statistics 2021-08-19 William Leeb

Stochastic approximation (SA) that involves multiple coupled sequences, known as multiple-sequence SA (MSSA), finds diverse applications in the fields of signal processing and machine learning. However, existing theoretical understandings…

Machine Learning · Computer Science 2024-10-18 Yue Huang , Zhaoxian Wu , Shiqian Ma , Qing Ling

In this paper, we tackle for the first time the problem of maximum likelihood (ML) estimation of the signal-to-noise ratio (SNR) parameter over time-varying single-input multiple-output (SIMO) channels. Both the data-aided (DA) and the…

Applications · Statistics 2014-11-19 Faouzi Bellili , Rabii Meftehi , Sofiene Affes , Alex Stephenne

Large sample size brings the computation bottleneck for modern data analysis. Subsampling is one of efficient strategies to handle this problem. In previous studies, researchers make more fo- cus on subsampling with replacement (SSR) than…

Machine Learning · Statistics 2015-11-24 Rong Zhu

We propose an algorithm to impute and forecast a time series by transforming the observed time series into a matrix, utilizing matrix estimation to recover missing values and de-noise observed entries, and performing linear regression to…

Machine Learning · Computer Science 2019-04-29 Anish Agarwal , Muhammad Jehangir Amjad , Devavrat Shah , Dennis Shen

In this paper, we present a stochastic gradient algorithm for minimizing a smooth objective function that is an expectation over noisy cost samples, and only the latter are observed for any given parameter. Our algorithm employs a gradient…

Optimization and Control · Mathematics 2023-07-03 Akash Mondal , Prashanth L. A. , Shalabh Bhatnagar

We study statistical properties of the optimal value and optimal solutions of the Sample Average Approximation of risk averse stochastic problems. Central Limit Theorem type results are derived for the optimal value and optimal solutions…

Optimization and Control · Mathematics 2016-03-25 Vincent Guigues , Volker Krätschmer , Alexander Shapiro

Evaluating mathematical reasoning in LLMs is constrained by limited benchmark sizes and inherent model stochasticity, yielding high-variance accuracy estimates and unstable rankings across platforms. On difficult problems, an LLM may fail…

Machine Learning · Computer Science 2026-02-04 Zihan Dong , Zhixian Zhang , Yang Zhou , Can Jin , Ruijia Wu , Linjun Zhang

Statistical divergences (SDs), which quantify the dissimilarity between probability distributions, are a basic constituent of statistical inference and machine learning. A modern method for estimating those divergences relies on…

Statistics Theory · Mathematics 2022-03-30 Sreejith Sreekumar , Ziv Goldfeld

The simultaneous estimation of many parameters based on data collected from corresponding studies is a key research problem that has received renewed attention in the high-dimensional setting. Many practical situations involve heterogeneous…

Methodology · Statistics 2026-03-26 Trambak Banerjee , Luella J. Fu , Gareth M. James , Gourab Mukherjee , Wenguang Sun

We propose a likelihood ratio statistic for forming hypothesis tests and confidence intervals for a nonparametrically estimated univariate regression function, based on the shape restriction of concavity (alternatively, convexity). Dealing…

Statistics Theory · Mathematics 2018-09-11 Charles R. Doss

Likelihood ratios are used for a variety of applications in particle physics data analysis, including parameter estimation, unfolding, and anomaly detection. When the data are high-dimensional, neural networks provide an effective tools for…

High Energy Physics - Phenomenology · Physics 2025-03-27 Fernando Torales Acosta , Tanvi Wamorkar , Vinicius Mikuni , Benjamin Nachman

We develop a multiscale scanning method to find anomalies in a $d$-dimensional random field in the presence of nuisance parameters. This covers the common situation that either the baseline-level or additional parameters such as the…

Applications · Statistics 2024-09-20 Claudia König , Axel Munk , Frank Werner

This paper studies the control-oriented identification problem of set-valued moving average systems with uniform persistent excitations and observation noises. A stochastic approximation-based (SA-based) algorithm without projections or…

Systems and Control · Electrical Eng. & Systems 2025-03-25 Jieming Ke , Ying Wang , Yanlong Zhao , Ji-Feng Zhang

In this paper, we show how to transform any optimization problem that arises from fitting a machine learning model into one that (1) detects and removes contaminated data from the training set while (2) simultaneously fitting the trimmed…

Machine Learning · Statistics 2017-02-07 Aleksandr Aravkin , Damek Davis

We propose Subsampling MCMC, a Markov Chain Monte Carlo (MCMC) framework where the likelihood function for $n$ observations is estimated from a random subset of $m$ observations. We introduce a highly efficient unbiased estimator of the…

Methodology · Statistics 2018-12-31 Matias Quiroz , Robert Kohn , Mattias Villani , Minh-Ngoc Tran

We consider an unconstrained problem of minimizing a smooth convex function which is only available through noisy observations of its values, the noise consisting of two parts. Similar to stochastic optimization problems, the first part is…

Optimization and Control · Mathematics 2020-09-22 Eduard Gorbunov , Pavel Dvurechensky , Alexander Gasnikov