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In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…

Medical Physics · Physics 2020-10-27 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is, therefore, challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable…

Medical Physics · Physics 2019-11-01 Wei Zhao , Tianling Lv , Peng Gao , Liyue Shen , Xianjin Dai , Kai Cheng , Mengyu Jia , Yang Chen , Lei Xing

Purpose: This study proposes a systematic method for determining the optimal x-ray tube settings/energy windows and fluence for minimal noise and maximum CNR in material density images obtained from DECT scans by fixing the subject size and…

Medical Physics · Physics 2023-08-02 Fatma Terzioglu , Emil Y. Sidky , Jp Phillips , Ingrid Reiser , Guillaume Bal , Xiaochuan Pan

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…

Medical Physics · Physics 2021-03-30 Matthew Tivnan , Grace Gang , Wenchao Cao , Nadav Shapira , Peter B. Noel , J. Webster Stayman

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…

Medical Physics · Physics 2018-03-19 Wei Zhao , Don Vernekohl , Fei Han , Bin Han , Hao Peng , Lei Xing , James K Min

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…

Medical Physics · Physics 2024-08-28 Qiaoxin Li , Ruifeng Chen , Peng Wang , Guotao Quan , Yanfeng Du , Dong Liang , Yinsheng Li

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with existing high-end DECT leveraging advanced X-ray…

Medical Physics · Physics 2024-08-13 Qiaoxin Li , Dong Liang , Yinsheng Li

Nonlinear systems of partial differential equations (PDEs) may permit several distinct solutions. The typical current approach to finding distinct solutions is to start Newton's method with many different initial guesses, hoping to find…

Numerical Analysis · Mathematics 2015-07-03 Patrick E. Farrell , Ásgeir Birkisson , Simon W. Funke

In clinical CT system, the x-ray tube emits polychromatic x-rays, and the x-ray detectors operate in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral equation. However,…

Medical Physics · Physics 2020-06-23 Wenxiang Cong , Bruno De Man , Ge Wang

Dual-energy computed tomography (DECT) is of great significance for clinical practice due to its huge potential to provide material-specific information. However, DECT scanners are usually more expensive than standard single-energy CT…

Medical Physics · Physics 2020-06-02 Tianling Lyu , Zhan Wu , Yikun Zhang , Yang Chen , Lei Xing , Wei Zhao

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

By acquiring two sets of tomographic measurements at distinct X-ray spectra, the dual-energy CT (DECT) enables quantitative material-specific imaging. However, the conventionally decomposed material basis images may encounter severe image…

We study a mathematical model describing the dynamics of dislocation densities in crystals. This model is expressed as a one-dimensional system of a parabolic equation and a first order Hamilton-Jacobi equation that are coupled together. We…

Analysis of PDEs · Mathematics 2007-05-23 Hassan Ibrahim

Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

The aim of hybrid inverse problems such as Acousto-Electric Tomography or Current Density Imaging is the reconstruction of the electrical conductivity in a domain that can only be accessed from its exterior. In the inversion procedure, the…

Functional Analysis · Mathematics 2023-10-12 Mikko Salo , Hjørdis Schlüter

Dual Energy Cone Beam Computed Tomography (DE-CBCT) is a promising technique for several medical applications, including dynamic angiography. Recently, a dynamical two-step method has been proposed : first, the water and iodine projections…

Medical Physics · Physics 2021-12-23 Frederic Jolivet , Georg Schramm , Johan Nuyts

Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…

Medical Physics · Physics 2017-06-29 Christian Möhler , Patrick Wohlfahrt , Christian Richter , Steffen Greilich

We present a monolithic parallel Newton-multigrid solver for nonlinear three dimensional fluid-structure interactions in Arbitrary Lagrangian Eulerian formulation. We start with a finite element discretization of the coupled problem, based…

Numerical Analysis · Mathematics 2020-08-11 L. Failer , T. Richter
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