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Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

Diffusion models have recently gained traction as a powerful class of deep generative priors, excelling in a wide range of image restoration tasks due to their exceptional ability to model data distributions. To solve image restoration…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Xiang Li , Soo Min Kwon , Shijun Liang , Ismail R. Alkhouri , Saiprasad Ravishankar , Qing Qu

Diffusion models for continuous data gained widespread adoption owing to their high quality generation and control mechanisms. However, controllable diffusion on discrete data faces challenges given that continuous guidance methods do not…

Diffusion Probabilistic Models (DPMs) have recently been employed for image deblurring, formulated as an image-conditioned generation process that maps Gaussian noise to the high-quality image, conditioned on the blurry input.…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Mengwei Ren , Mauricio Delbracio , Hossein Talebi , Guido Gerig , Peyman Milanfar

Diffusion models have shown significant potential in generating oracle items that best match user preference with guidance from user historical interaction sequences. However, the quality of guidance is often compromised by unpredictable…

Information Retrieval · Computer Science 2025-05-20 Wenyu Mao , Zhengyi Yang , Jiancan Wu , Haozhe Liu , Yancheng Yuan , Xiang Wang , Xiangnan He

Masked discrete diffusion models (MDMs) are a promising new approach to generative modelling, offering the ability for parallel token generation and therefore greater efficiency than autoregressive counterparts. However, achieving an…

Machine Learning · Computer Science 2026-03-02 David Fox , Sam Bowyer , Song Liu , Laurence Aitchison , Raul Santos-Rodriguez , Mengyue Yang

Diffusion models have demonstrated exceptional efficacy in various generative applications. While existing models focus on minimizing a weighted sum of denoising score matching losses for data distribution modeling, their training primarily…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Ling Yang , Haotian Qian , Zhilong Zhang , Jingwei Liu , Bin Cui

Diffusion models generate high-quality images but require dozens of forward passes. We introduce Distribution Matching Distillation (DMD), a procedure to transform a diffusion model into a one-step image generator with minimal impact on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Tianwei Yin , Michaël Gharbi , Richard Zhang , Eli Shechtman , Fredo Durand , William T. Freeman , Taesung Park

Diffusion model (DM) based adversarial purification (AP) has proven to be a powerful defense method that can remove adversarial perturbations and generate a purified example without threats. In principle, the pre-trained DMs can only ensure…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Guang Lin , Zerui Tao , Jianhai Zhang , Toshihisa Tanaka , Qibin Zhao

Sampling from unnormalized densities is analogous to the generative modeling problem, but the target distribution is defined by a known energy function instead of data samples. Because evaluating the energy function is often costly, a…

Machine Learning · Computer Science 2026-05-06 Aaron Havens , Brian Karrer , Neta Shaul

AI-assisted protein design has emerged as a critical tool for advancing biotechnology, as deep generative models have demonstrated their reliability in this domain. However, most existing models primarily utilize protein sequence or…

Computational Engineering, Finance, and Science · Computer Science 2026-05-27 Changjian Zhou , Yuexi Qiu , Jia Song

Denoising diffusion models (DDMs) have attracted attention for their exceptional generation quality and diversity. This success is largely attributed to the use of class- or text-conditional diffusion guidance methods, such as classifier…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Susung Hong , Gyuseong Lee , Wooseok Jang , Seungryong Kim

Diffusion model distillation has emerged as a powerful technique for creating efficient few-step and single-step generators. Among these, Distribution Matching Distillation (DMD) and its variants stand out for their impressive performance,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Dongyang Liu , Peng Gao , David Liu , Ruoyi Du , Zhen Li , Qilong Wu , Xin Jin , Sihan Cao , Shifeng Zhang , Hongsheng Li , Steven Hoi

Dataset distillation enables efficient training by distilling the information of large-scale datasets into significantly smaller synthetic datasets. Diffusion based paradigms have emerged in recent years, offering novel perspectives for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Qichao Wang , Yunhong Lu , Hengyuan Cao , Junyi Zhang , Min Zhang

Balancing content fidelity and artistic style is a pivotal challenge in image generation. While traditional style transfer methods and modern Denoising Diffusion Probabilistic Models (DDPMs) strive to achieve this balance, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Nadav Z. Cohen , Oron Nir , Ariel Shamir

Diffusion models typically generate data through a fixed denoising trajectory that is shared across all samples. However, generation targets can differ in complexity, suggesting that a single pre-defined diffusion process may not be optimal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Yucheng Xing , Xiaodong Liu , Xin Wang

Recent advances in diffusion models attempt to handle conditional generative tasks by utilizing a differentiable loss function for guidance without the need for additional training. While these methods achieved certain success, they often…

Machine Learning · Computer Science 2024-07-08 Lingxiao Yang , Shutong Ding , Yifan Cai , Jingyi Yu , Jingya Wang , Ye Shi

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

We propose residual denoising diffusion models (RDDM), a novel dual diffusion process that decouples the traditional single denoising diffusion process into residual diffusion and noise diffusion. This dual diffusion framework expands the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Jiawei Liu , Qiang Wang , Huijie Fan , Yinong Wang , Yandong Tang , Liangqiong Qu

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu