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The accurate identification of antiviral peptides (AVPs) is crucial for novel drug development. However, existing methods still have limitations in capturing complex sequence dependencies and distinguishing confusing samples with high…

Machine Learning · Computer Science 2026-01-19 Xinru Wen , Weizhong Lin , zi liu , Xuan Xiao

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

Recent successes in deep learning based deformable image registration (DIR) methods have demonstrated that complex deformation can be learnt directly from data while reducing computation time when compared to traditional methods. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Sharib Ali , Jens Rittscher

B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to…

Quantitative Methods · Quantitative Biology 2021-03-23 Bhargab Ghoshal , Biraja Ghoshal , Stephen Swift , Allan Tucker

As deep learning models become increasingly bigger and more complex, it is critical to improve model training and inference efficiency. Though a variety of highly optimized libraries and packages (known as DL kernels) have been developed,…

Software Engineering · Computer Science 2024-08-22 Ruixin Wang , Minghai Lu , Cody Hao Yu , Yi-Hsiang Lai , Tianyi Zhang

Graph neural networks (GNNs) excel on homophilic graphs where connected nodes share labels, but struggle with heterophilic graphs where edges do not imply similarity. Moreover, iterative message passing limits scalability due to…

Machine Learning · Computer Science 2026-02-16 Turja Kundu , Sanjukta Bhowmick

The goal of Protein Structure Prediction (PSP) problem is to predict a protein's 3D structure (confirmation) from its amino acid sequence. The problem has been a 'holy grail' of science since the Noble prize-winning work of Anfinsen…

Biomolecules · Quantitative Biology 2023-01-24 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Hang Lou , Hao Ni , Ross D. King

Increasingly, malwares are becoming complex and they are spreading on networks targeting different infrastructures and personal-end devices to collect, modify, and destroy victim information. Malware behaviors are polymorphic, metamorphic,…

Cryptography and Security · Computer Science 2022-11-09 Lionel Nganyewou Tidjon , Foutse Khomh

Deep learning models have enjoyed great success for image related computer vision tasks like image classification and object detection. For video related tasks like human action recognition, however, the advancements are not as significant…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Xiaolin Song , Cuiling Lan , Wenjun Zeng , Junliang Xing , Jingyu Yang , Xiaoyan Sun

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding,…

Methodology · Statistics 2025-08-29 Susan Ellul , Stijn Vansteelandt , John B. Carlin , Margarita Moreno-Betancur

Constrained image splicing detection and localization (CISDL) is a newly proposed challenging task for image forensics, which investigates two input suspected images and identifies whether one image has suspected regions pasted from the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Yaqi Liu , Xianfeng Zhao , Xiaobin Zhu , Yun Cao

Purpose: To propose a wave-encoded model-based deep learning (wave-MoDL) strategy for highly accelerated 3D imaging and joint multi-contrast image reconstruction, and further extend this to enable rapid quantitative imaging using an…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Jaejin Cho , Borjan Gagoski , Taehyung Kim , Qiyuan Tian , Stephen Robert Frost , Itthi Chatnuntawech , Berkin Bilgic

Deep Learning (DL) can predict biomarkers directly from digitized cancer histology in a weakly-supervised setting. Recently, the prediction of continuous biomarkers through regression-based DL has seen an increasing interest. Nonetheless,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Omar S. M. El Nahhas , Georg Wölflein , Marta Ligero , Tim Lenz , Marko van Treeck , Firas Khader , Daniel Truhn , Jakob Nikolas Kather

Deconvolution of large survey images with millions of galaxies requires to develop a new generation of methods which can take into account a space variant Point Spread Function (PSF) and have to be at the same time accurate and fast. We…

Instrumentation and Methods for Astrophysics · Physics 2020-09-16 Florent Sureau , Alexis Lechat , Jean-Luc Starck

Deep Reinforcement Learning (DRL) has emerged as a promising approach for solving Combinatorial Optimization (CO) problems, such as the 3D Bin Packing Problem (3D-BPP), Traveling Salesman Problem (TSP), or Vehicle Routing Problem (VRP), but…

Machine Learning · Computer Science 2026-01-30 Han Fang , Paul Weng , Yutong Ban

Information diffusion prediction (IDP) is a pivotal task for understanding how information propagates among users. Most existing methods commonly adhere to a conventional training-test paradigm, where models are pretrained on training data…

Social and Information Networks · Computer Science 2025-07-18 Wenting Zhu , Chaozhuo Li , Qingpo Yang , Xi Zhang , Philip S. Yu

The COVID-19 pandemic has initiated a global health emergency, with an exigent need for effective cure. Progressively, drug repurposing is emerging a promise solution as it saves the time, cost and labor. However, the number of drug…

Biomolecules · Quantitative Biology 2024-06-25 Imra Aqeel , Abdul Majid

We develop a framework for comparing data manifolds, aimed, in particular, towards the evaluation of deep generative models. We describe a novel tool, Cross-Barcode(P,Q), that, given a pair of distributions in a high-dimensional space,…

High-fidelity face digitization solutions often combine multi-view stereo (MVS) techniques for 3D reconstruction and a non-rigid registration step to establish dense correspondence across identities and expressions. A common problem is the…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Tianye Li , Shichen Liu , Timo Bolkart , Jiayi Liu , Hao Li , Yajie Zhao

Topological Data Analysis (TDA) provides tools to describe the shape of data, but integrating topological features into deep learning pipelines remains challenging, especially when preserving local geometric structure rather than…

Machine Learning · Computer Science 2026-04-21 Elena Xinyi Wang , Arnur Nigmetov , Dmitriy Morozov