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Thematic analysis provides valuable insights into participants' experiences through coding and theme development, but its resource-intensive nature limits its use in large healthcare studies. Large language models (LLMs) can analyze text at…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Background: Large language models (LLMs) have demonstrated substantial potential to support clinical practice. Other than Chat GPT4 and its predecessors, few LLMs, especially those of the leading and more powerful reasoning model class,…

Computation and Language · Computer Science 2025-06-04 Richard Armitage

The capabilities of Large Language Models (LLMs) have significantly evolved, extending from natural language processing to complex tasks like code understanding and generation. We expand the scope of LLMs' capabilities to a broader context,…

Computation and Language · Computer Science 2024-10-11 Chenyang Lyu , Lecheng Yan , Rui Xing , Wenxi Li , Younes Samih , Tianbo Ji , Longyue Wang

OpenAI's latest large vision-language model (LVLM), GPT-4V(ision), has piqued considerable interest for its potential in medical applications. Despite its promise, recent studies and internal reviews highlight its underperformance in…

Computation and Language · Computer Science 2023-12-13 Pengcheng Chen , Ziyan Huang , Zhongying Deng , Tianbin Li , Yanzhou Su , Haoyu Wang , Jin Ye , Yu Qiao , Junjun He

We introduce OPENXRD, a comprehensive benchmarking framework for evaluating large language models (LLMs) and multimodal LLMs (MLLMs) in crystallography question answering. The framework measures context assimilation, or how models use…

Computation and Language · Computer Science 2026-03-11 Ali Vosoughi , Ayoub Shahnazari , Yufeng Xi , Zeliang Zhang , Griffin Hess , Chenliang Xu , Niaz Abdolrahim

Deploying Large Language Models (LLMs) for question answering (QA) over lengthy contexts is a significant challenge. In industrial settings, this process is often hindered by high computational costs and latency, especially when multiple…

Computation and Language · Computer Science 2025-09-29 Xiliang Zhu , Shi Zong , David Rossouw

Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and…

Computation and Language · Computer Science 2025-08-08 Stefan Lenz , Arsenij Ustjanzew , Marco Jeray , Meike Ressing , Torsten Panholzer

Large Language Models (LLMs) have grown increasingly powerful, yet ensuring their decisions remain transparent and trustworthy requires self-consistency -- no contradictions in their internal reasoning. Our study reveals that even on simple…

Computation and Language · Computer Science 2025-06-24 Zhenru Lin , Jiawen Tao , Yang Yuan , Andrew Chi-Chih Yao

Artificially intelligent (AI) co-scientists must be able to sift through research literature cost-efficiently while applying nuanced scientific reasoning. We evaluate Small Language Models (SLMs, <= 8B parameters) for classifying medical…

Computational Engineering, Finance, and Science · Computer Science 2025-12-09 Muhammed Muaaz Dawood , Mohammad Zaid Moonsamy , Kaela Kokkas , Hairong Wang , Robert F. Breiman , Richard Klein , Emmanuel K. Sekyi , Bruce A. Bassett

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

LLMs have become increasingly capable at accomplishing a range of specialized-tasks and can be utilized to expand equitable access to medical knowledge. Most medical LLMs have involved extensive fine-tuning, leveraging specialized medical…

Fine-tuning Large Language Models (LLMs) incurs considerable training costs, driving the need for data-efficient training with optimised data ordering. Human-inspired strategies offer a solution by organising data based on human learning…

Computation and Language · Computer Science 2024-11-06 Yushi Yang , Andrew M. Bean , Robert McCraith , Adam Mahdi

Large language models (LLMs) show promise in radiology but their deployment is limited by computational requirements that preclude use in resource-constrained clinical environments. We investigate whether small language models (SLMs) of 3-4…

Computation and Language · Computer Science 2026-05-05 Pankaj Gupta , Kartik Bose

Large Language Models (LLMs) are increasingly deployed for open-domain question answering, yet their alignment with human perspectives on temporally recent information remains underexplored. We introduce RECOM (Reddit Evaluation for…

Computation and Language · Computer Science 2026-02-13 Pushwitha Krishnappa , Amit Das , Vinija Jain , Tathagata Mukherjee , Aman Chadha

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Large Language Models (LLMs) are increasingly used in intelligent systems that perform reasoning, summarization, and code generation. Their ability to follow natural-language instructions, while powerful, also makes them vulnerable to a new…

Cryptography and Security · Computer Science 2025-11-13 Daniyal Ganiuly , Assel Smaiyl

Large Language Models (LLMs) represent a major step toward artificial general intelligence, significantly advancing our ability to interact with technology. While LLMs perform well on Natural Language Processing tasks -- such as…

Computation and Language · Computer Science 2025-05-15 Brandon Smith , Mohamed Reda Bouadjenek , Tahsin Alamgir Kheya , Phillip Dawson , Sunil Aryal

Large Language Models (LLMs) have made great strides in recent years to achieve unprecedented performance across different tasks. However, due to commercial interest, the most competitive models like GPT, Gemini, and Claude have been gated…

Large Language Models (LLMs) have revolutionized inference across diverse natural language tasks, with larger models performing better but at higher computational costs. We propose a confidence-driven strategy that dynamically selects the…

Computation and Language · Computer Science 2026-02-26 Bo-Wei Chen , Chung-Chi Chen , An-Zi Yen