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In the face of the stupefying complexity of the human brain, network analysis is a most useful tool that allows one to greatly simplify the problem, typically by approximating the billions of neurons comprising the brain by means of a…

Neurons and Cognition · Quantitative Biology 2023-10-03 Youssef Kora , Christoph Simon

Digital phenotyping in mental health often consists of collecting behavioral and experience-based information through sensory and self-reported data from devices such as smartphones. Such rich and comprehensive data could be used to develop…

Social and Information Networks · Computer Science 2023-12-05 Andy Davies , Eiko Fried , Hane Aung , Omar Costilla-Reyes

Deducing the structure of neural circuits is one of the central problems of modern neuroscience. Recently-introduced calcium fluorescent imaging methods permit experimentalists to observe network activity in large populations of neurons,…

Applications · Statistics 2011-07-22 Yuriy Mishchencko , Joshua T. Vogelstein , Liam Paninski

Decoding the heterogeneity of biological neural systems is key to understanding the nervous system's complex dynamical behaviors. This study analyzes the comprehensive Drosophila brain connectome, which is the most recent data set,…

Neurons and Cognition · Quantitative Biology 2025-10-01 Xiaoyu Zhang , Pengcheng Yang , Yifei Zhang , Bowei Qin , Qiang Luo , Wei Lin , Xin Lu

Connectomics is an emerging field in neuroscience that aims to reconstruct the 3-dimensional morphology of neurons from electron microscopy (EM) images. Recent studies have successfully demonstrated the use of convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-02-27 Shibani Santurkar , David Budden , Alexander Matveev , Heather Berlin , Hayk Saribekyan , Yaron Meirovitch , Nir Shavit

Organisms move through the world by changing their shape, and here we explore the mapping from shape space to movements in the nematode C. elegans as it crawls on a planar agar surface. We characterize the statistics of the trajectories…

Neurons and Cognition · Quantitative Biology 2016-01-05 Greg J Stephens , Bethany Johnson-Kerner , William Bialek , William S Ryu

We analyze the complex networks associated with brain electrical activity. Multichannel EEG measurements are first processed to obtain 3D voxel activations using the tomographic algorithm LORETA. Then, the correlation of the current…

Biological Physics · Physics 2007-05-23 G. Ruffini , C. Ray , J. Marco , L. Fuentemilla , C. Grau

Morphology based analysis of cell types has been an area of great interest to the neuroscience community for several decades. Recently, high resolution electron microscopy (EM) datasets of the mouse brain have opened up opportunities for…

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

The promise of large-scale, high-resolution datasets from Electron Microscopy (EM) and X-ray Microtomography (XRM) lies in their ability to reveal neural structures and synaptic connectivity, which is critical for understanding the brain.…

A major challenge in analyzing animal behavior is to discover some underlying simplicity in complex motor actions. Here we show that the space of shapes adopted by the nematode C. elegans is surprisingly low dimensional, with just four…

Other Quantitative Biology · Quantitative Biology 2016-01-05 Greg J Stephens , Bethany Johnson-Kerner , William Bialek , William S Ryu

Researchers continue exploring neurons' intricate patterns of activity in the cerebral visual cortex in response to visual stimuli. The way neurons communicate and optimize their interactions with each other under different experimental…

Neurons and Cognition · Quantitative Biology 2024-02-09 Lauren Miako Beede , Giuseppe Vinci

The HuggingFace Datasets Hub hosts thousands of datasets, offering exciting opportunities for language model training and evaluation. However, datasets for a specific task type often have different schemas, making harmonization challenging.…

Computation and Language · Computer Science 2023-05-17 Damien Sileo

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and productivity losses for humans and livestock. The limited number of anthelmintics (or antinematode drugs) available today to treat these…

Quantitative Methods · Quantitative Biology 2022-05-30 Xianting Ding , Zach Njus , Taejoon Kong , Wenqiong Su , Chih-Ming Ho , Santosh Pandey

Cerebellar-like networks, in which input activity patterns are separated by projection to a much higher-dimensional space before classification, are a recurring neurobiological motif, present in the cerebellum, dentate gyrus, insect…

Neurons and Cognition · Quantitative Biology 2026-03-23 William Dorrell , Peter E. Latham

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

Neurons and Cognition · Quantitative Biology 2020-09-08 Steve Mehrkanoon

In the past decade, the cell-type specific connectivity and activity of local cortical networks have been characterized experimentally to some detail. In parallel, modeling has been established as a tool to relate network structure to…

Neurons and Cognition · Quantitative Biology 2011-06-29 Tobias C. Potjans , Markus Diesmann

We investigate the adaptation and performance of modularity-based algorithms, designed in the scope of complex networks, to analyze the mesoscopic structure of correlation matrices. Using a multi-resolution analysis we are able to describe…

Data Analysis, Statistics and Probability · Physics 2011-03-31 Clara Granell , Sergio Gomez , Alex Arenas