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Naive Retrieval-Augmented Generation (RAG) focuses on individual documents during retrieval and, as a result, falls short in handling networked documents which are very popular in many applications such as citation graphs, social media, and…

Machine Learning · Computer Science 2025-07-15 Yuntong Hu , Zhihan Lei , Zheng Zhang , Bo Pan , Chen Ling , Liang Zhao

We present a novel extension to Retrieval Augmented Generation with the goal of mitigating factual inaccuracies in the output of large language models. Specifically, our method draws on the cognitive linguistic theory of frame semantics for…

Computation and Language · Computer Science 2024-06-25 Harish Tayyar Madabushi

Deep generative models are attracting great attention for molecular design with desired properties. Most existing models generate molecules by sequentially adding atoms. This often renders generated molecules with less correlation with…

Machine Learning · Computer Science 2021-11-29 Seonghwan Seo , Jaechang Lim , Woo Youn Kim

Deploying Large Language Model (LLM) applications, particularly those relying on Retrieval-Augmented Generation (RAG), remains challenging due to high computational demands, outdated knowledge bases, and the need to manually select optimal…

Recent advancements in large language models (LLMs) and multi-modal LLMs have been remarkable. However, these models still rely solely on their parametric knowledge, which limits their ability to generate up-to-date information and…

Artificial Intelligence · Computer Science 2025-04-22 Zihan Ling , Zhiyao Guo , Yixuan Huang , Yi An , Shuai Xiao , Jinsong Lan , Xiaoyong Zhu , Bo Zheng

Current state-of-the-art large language models are effective in generating high-quality text and encapsulating a broad spectrum of world knowledge. These models, however, often hallucinate and lack locally relevant factual data.…

Software Engineering · Computer Science 2024-02-21 Anton Shapkin , Denis Litvinov , Yaroslav Zharov , Egor Bogomolov , Timur Galimzyanov , Timofey Bryksin

Retrieval-augmented Generation (RAG) has markedly enhanced the capabilities of Large Language Models (LLMs) in tackling knowledge-intensive tasks. The increasing demands of application scenarios have driven the evolution of RAG, leading to…

Computation and Language · Computer Science 2024-08-01 Yunfan Gao , Yun Xiong , Meng Wang , Haofen Wang

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Despite their remarkable capabilities, large language models (LLMs) often produce responses containing factual inaccuracies due to their sole reliance on the parametric knowledge they encapsulate. Retrieval-Augmented Generation (RAG), an ad…

Computation and Language · Computer Science 2023-10-19 Akari Asai , Zeqiu Wu , Yizhong Wang , Avirup Sil , Hannaneh Hajishirzi

Searching for novel molecular compounds with desired properties is an important problem in drug discovery. Many existing frameworks generate molecules one atom at a time. We instead propose a flexible editing paradigm that generates…

Biomolecules · Quantitative Biology 2021-11-02 Benson Chen , Xiang Fu , Regina Barzilay , Tommi Jaakkola

This paper presents a comprehensive study of Retrieval-Augmented Generation (RAG), tracing its evolution from foundational concepts to the current state of the art. RAG combines retrieval mechanisms with generative language models to…

Computation and Language · Computer Science 2024-10-18 Shailja Gupta , Rajesh Ranjan , Surya Narayan Singh

Case-based reasoning (CBR) is an experience-based approach to problem solving, where a repository of solved cases is adapted to solve new cases. Recent research shows that Large Language Models (LLMs) with Retrieval-Augmented Generation…

Artificial Intelligence · Computer Science 2025-01-10 Ofir Marom

Predicting how cells respond to genetic perturbations is fundamental to understanding gene function, disease mechanisms, and therapeutic development. While recent deep learning approaches have shown promise in modeling single-cell…

Machine Learning · Computer Science 2026-03-10 Andrea Giuseppe Di Francesco , Andrea Rubbi , Pietro Liò

Traditional Retrieval-Augmented Generation (RAG) methods are limited by their reliance on a fixed number of retrieved documents, often resulting in incomplete or noisy information that undermines task performance. Although recent adaptive…

Computation and Language · Computer Science 2024-10-16 Wenjia Zhai

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Diffusion models enable high-quality and diverse visual content synthesis. However, they struggle to generate rare or unseen concepts. To address this challenge, we explore the usage of Retrieval-Augmented Generation (RAG) with image…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Rotem Shalev-Arkushin , Rinon Gal , Amit H. Bermano , Ohad Fried

Retrieval-augmented generation (RAG) has emerged as a promising technology for addressing hallucination issues in the responses generated by large language models (LLMs). Existing studies on RAG primarily focus on applying semantic-based…

Computation and Language · Computer Science 2025-02-12 Xiangrong Zhu , Yuexiang Xie , Yi Liu , Yaliang Li , Wei Hu

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Retrieval-augmented generation (RAG) techniques have emerged as a promising solution to enhance the reliability of large language models (LLMs) by addressing issues like hallucinations, outdated knowledge, and domain adaptation. In…

Computation and Language · Computer Science 2025-01-28 Weihang Su , Yichen Tang , Qingyao Ai , Junxi Yan , Changyue Wang , Hongning Wang , Ziyi Ye , Yujia Zhou , Yiqun Liu

Retrieval-Augmented Generation (RAG) has become a foundational paradigm for equipping large language models (LLMs) with external knowledge, playing a critical role in information retrieval and knowledge-intensive applications. However,…

Computation and Language · Computer Science 2025-06-10 Weihang Su , Qingyao Ai , Jingtao Zhan , Qian Dong , Yiqun Liu