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Alzheimer's disease (AD) progresses from asymptomatic changes to clinical symptoms, emphasizing the importance of early detection for proper treatment. Functional magnetic resonance imaging (fMRI), particularly dynamic functional network…

Computational Engineering, Finance, and Science · Computer Science 2024-08-02 Yuxiang Wei , Anees Abrol , James Lah , Deqiang Qiu , Vince D. Calhoun

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

The biological definition of Alzheimer's disease (AD) relies on multi-modal neuroimaging, yet the clinical utility of positron emission tomography (PET) is limited by cost and radiation exposure, hindering early screening at preclinical or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Tuo Liu , Shuijin Lin , Shaozhen Yan , Haifeng Wang , Jie Lu , Jianhua Ma , Chunfeng Lian

Unsupervised anomaly detection is a popular approach for the analysis of neuroimaging data as it allows to identify a wide variety of anomalies from unlabelled data. It relies on building a subject-specific model of healthy appearance to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Maëlys Solal , Ravi Hassanaly , Ninon Burgos

Objectives: The objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease (AD) prediction and to highlight the potential of AI techniques in improving early AD…

Machine Learning · Computer Science 2024-06-27 Thorsten Rudroff , Oona Rainio , Riku Klén

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Early diagnosis of Alzheimer's disease is a challenge because the existing methodologies do not identify the patients in their preclinical stage, which can last up to a decade prior to the onset of clinical symptoms. Several research…

Machine Learning · Computer Science 2024-01-03 Vivek Kumar Tiwari , Premananda Indic , Shawana Tabassum

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Alzheimer's disease (AD) is an irreversible neurode generative disease of the brain.The disease may causes memory loss, difficulty communicating and disorientation. For the diagnosis of Alzheimer's disease, a series of scales are often…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Yelu Gao , Huang Huang , Lian Zhang

Alzheimer's disease is a neurogenerative disease that alters memories, cognitive functions leading to death. Early diagnosis of the disease, by detection of the preliminary stage, called Mild Cognitive Impairment (MCI), remains a…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Achraf Ben Miled , Taoufik Yeferny , Amira ben Rabeh

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

Computer Vision and Pattern Recognition · Computer Science 2017-12-21 Jyoti Islam , Yanqing Zhang

In this paper, we introduce a deep learning model to classify children as either healthy or potentially autistic with 94.6% accuracy using Deep Learning. Autistic patients struggle with social skills, repetitive behaviors, and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-10 Madison Beary , Alex Hadsell , Ryan Messersmith , Mohammad-Parsa Hosseini

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-$\beta$ (A$\beta$) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This…

Molecular Networks · Quantitative Biology 2025-12-05 She Xutong

Positron Emission Tomography (PET) is an important tool for studying Alzheimer's disease (AD). PET scans can be used as diagnostics tools, and to provide molecular characterization of patients with cognitive disorders. However, multiple…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Bo Zhou , Rui Wang , Ming-Kai Chen , Adam P. Mecca , Ryan S. O'Dell , Christopher H. Van Dyck , Richard E. Carson , James S. Duncan , Chi Liu

The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

Artificial Intelligence · Computer Science 2021-08-11 Changhyun Park , Heung-Il Suk

Purpose: To examine whether incorporating anatomical awareness into a deep learning model can improve generalizability and enable prediction of disease progression. Methods: This retrospective multicenter study included conventional pelvic…

Reinforcement learning (RL) has recently shown promise in predicting Alzheimer's disease (AD) progression due to its unique ability to model domain knowledge. However, it is not clear which RL algorithms are well-suited for this task.…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs survival and quality of life. While anti-amyloid beta (Abeta) therapies can slow disease progression, their efficacy depends on personalized dosing…

Optimization and Control · Mathematics 2025-11-10 Sun Lee , Chiu-Yen Kao , Zhiyuan Li , Tingting Dan , Guorong Wu , Wenrui Hao
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