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Goal-oriented de novo molecule design, namely generating molecules with specific property or substructure constraints, is a crucial yet challenging task in drug discovery. Existing methods, such as Bayesian optimization and reinforcement…

Computational Engineering, Finance, and Science · Computer Science 2025-02-28 Chuanliu Fan , Ziqiang Cao , Zicheng Ma , Nan Yu , Yimin Peng , Jun Zhang , Yiqin Gao , Guohong Fu

Deploying Large Language Models (LLMs) on edge devices enhances privacy but faces performance hurdles due to limited resources. We introduce a systematic methodology to evaluate on-device LLMs, balancing capability, efficiency, and resource…

1-bit LLM quantization offers significant advantages in reducing storage and computational costs. However, existing methods typically train 1-bit LLMs from scratch, failing to fully leverage pre-trained models. This results in high training…

Computation and Language · Computer Science 2026-05-19 Zhijun Tu , Jian Li , Yuanyuan Xi , Siqi Liu , Chuanjian Liu , Hanting Chen , Jie Hu , Yunhe Wang

The growing demand for Large Language Models (LLMs) in applications such as content generation, intelligent chatbots, and sentiment analysis poses considerable challenges for LLM service providers. To efficiently use GPU resources and boost…

Machine Learning · Computer Science 2024-04-17 Yilong Zhao , Chien-Yu Lin , Kan Zhu , Zihao Ye , Lequn Chen , Size Zheng , Luis Ceze , Arvind Krishnamurthy , Tianqi Chen , Baris Kasikci

Large Language Models (LLMs) have shown an impressive capability in code generation. The LLM effectiveness generally increases with its size: The higher the number of LLM's trainable parameters the better its ability to implement code.…

Software Engineering · Computer Science 2026-01-28 Alessandro Giagnorio , Antonio Mastropaolo , Saima Afrin , Massimiliano Di Penta , Gabriele Bavota

The deployment of large language models (LLMs) is increasingly constrained by memory and latency bottlenecks, motivating the need for quantization techniques that flexibly balance accuracy and efficiency. Recent work has introduced…

Machine Learning · Computer Science 2026-02-03 Gunho Park , Jeongin Bae , Beomseok Kwon , Byeongwook Kim , Se Jung Kwon , Dongsoo Lee

Large Language Models (LLMs) have achieved state-of-the-art performance across various language tasks but pose challenges for practical deployment due to their substantial memory requirements. Furthermore, the latest generative models…

Machine Learning · Computer Science 2023-08-22 Young Jin Kim , Rawn Henry , Raffy Fahim , Hany Hassan Awadalla

Large language models (LLMs) have revolutionized language processing, delivering outstanding results across multiple applications. However, deploying LLMs on edge devices poses several challenges with respect to memory, energy, and compute…

Computation and Language · Computer Science 2024-10-07 Fuwen Tan , Royson Lee , Łukasz Dudziak , Shell Xu Hu , Sourav Bhattacharya , Timothy Hospedales , Georgios Tzimiropoulos , Brais Martinez

Large language models (LLMs) have demonstrated impressive abilities in various domains while the inference cost is expensive. Many previous studies exploit quantization methods to reduce LLM inference cost by reducing latency and memory…

Machine Learning · Computer Science 2024-11-12 Jinhao Li , Jiaming Xu , Shiyao Li , Shan Huang , Jun Liu , Yaoxiu Lian , Guohao Dai

Recently, considerable efforts have been directed towards compressing Large Language Models (LLMs), which showcase groundbreaking capabilities across diverse applications but entail significant deployment costs due to their large sizes.…

Machine Learning · Computer Science 2024-06-24 Yeonhong Park , Jake Hyun , SangLyul Cho , Bonggeun Sim , Jae W. Lee

Deploying large language models (LLMs) in resource-constrained environments is hindered by heavy computational and memory requirements. We present LBLLM, a lightweight binarization framework that achieves effective W(1+1)A4 quantization…

Machine Learning · Computer Science 2026-04-22 Siqing Song , Chuang Wang , Yong Lang , Yi Yang , Xu-Yao Zhang

The substantial memory bandwidth and computational demands of large language models (LLMs) present critical challenges for efficient inference. To tackle this, the literature has explored heterogeneous systems that combine neural processing…

Hardware Architecture · Computer Science 2026-05-05 Yuzong Chen , Chao Fang , Xilai Dai , Yuheng Wu , Thierry Tambe , Marian Verhelst , Mohamed S. Abdelfattah

While Large Language Models (LLMs) have significantly advanced code generation efficiency, they face inherent challenges in balancing performance and inference costs across diverse programming tasks. Dynamically selecting the optimal LLM…

Software Engineering · Computer Science 2025-06-13 Junhang Cheng , Fang Liu , Chengru Wu , Li Zhang

Recent research, such as BitNet, is paving the way for a new era of 1-bit Large Language Models (LLMs). In this work, we introduce a 1-bit LLM variant, namely BitNet b1.58, in which every single parameter (or weight) of the LLM is ternary…

Computation and Language · Computer Science 2024-02-28 Shuming Ma , Hongyu Wang , Lingxiao Ma , Lei Wang , Wenhui Wang , Shaohan Huang , Li Dong , Ruiping Wang , Jilong Xue , Furu Wei

In this paper, we explore FP8 low-bit data formats for efficient training of large language models (LLMs). Our key insight is that most variables, such as gradients and optimizer states, in LLM training can employ low-precision data formats…

Recent advancements in Large Language Models (LLMs) have demonstrated impressive capabilities as their scale expands to billions of parameters. Deploying these large-scale models on resource-constrained platforms presents significant…

Hardware Architecture · Computer Science 2025-05-15 Keran Zheng , Yinting Huang , Zhewen Yu , Christos-Savvas Bouganis

State-of-the-art language models (LMs) represented by long-short term memory recurrent neural networks (LSTM-RNNs) and Transformers are becoming increasingly complex and expensive for practical applications. Low-bit neural network…

Computation and Language · Computer Science 2021-12-22 Junhao Xu , Jianwei Yu , Shoukang Hu , Xunying Liu , Helen Meng

Large language models (LLMs) face significant computational and memory challenges, making extremely low-bit quantization crucial for their efficient deployment. In this work, we introduce SDQ-LLM: Sigma-Delta Quantization for 1-bit LLMs of…

Machine Learning · Computer Science 2025-10-07 Junhao Xia , Ming Zhao , Limin Xiao , Xiujun Zhang

In the evolving landscape of transportation systems, integrating Large Language Models (LLMs) offers a promising frontier for advancing intelligent decision-making across various applications. This paper introduces a novel 3-dimensional…

Machine Learning · Computer Science 2024-12-17 Dexter Le , Aybars Yunusoglu , Karn Tiwari , Murat Isik , I. Can Dikmen

We propose a memory-efficient finetuning algorithm for large language models (LLMs) that supports finetuning LLMs with 65B parameters in 2/3/4-bit precision on as little as one 24GB GPU. Our method, modular low-rank adaptation (ModuLoRA),…

Machine Learning · Computer Science 2024-03-12 Junjie Yin , Jiahao Dong , Yingheng Wang , Christopher De Sa , Volodymyr Kuleshov