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High-throughput 3D quantitative phase imaging (QPI) in flow cytometry enables label-free, volumetric characterization of individual cells by reconstructing their refractive index (RI) distributions from multiple viewing angles during flow…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Enze Ye , Wei Lin , Shaochi Ren , Yakun Liu , Xiaoping Li , Hao Wang , He Sun , Feng Pan

Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties up to several centimeters deep in tissue, creating the potential for numerous exciting clinical…

Medical Physics · Physics 2021-04-15 Janek Gröhl , Melanie Schellenberg , Kris Dreher , Lena Maier-Hein

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

Large-scale contrastive vision-language pre-trained models provide the zero-shot model achieving competitive performance across a range of image classification tasks without requiring training on downstream data. Recent works have confirmed…

Machine Learning · Computer Science 2024-04-02 Giung Nam , Byeongho Heo , Juho Lee

Artificial intelligence (AI) methodologies hold great promise for the rapid and accurate diagnosis of coronary artery disease (CAD) from intravascular optical coherent tomography (IVOCT) images. Numerous papers have been published…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Xu Chen , Yuan Huang , Benn Jessney , Jason Sangha , Sophie Gu , Carola-Bibiane Schönlieb , Martin Bennett , Michael Roberts

Cardiac magnetic resonance imaging (CMR), considered the gold standard for noninvasive cardiac assessment, is a diverse and complex modality requiring a wide variety of image processing tasks for comprehensive assessment of cardiac…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Athira J Jacob , Indraneel Borgohain , Teodora Chitiboi , Puneet Sharma , Dorin Comaniciu , Daniel Rueckert

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

We present an end-to-end automated workflow that uses large-scale remote compute resources and an embedded GPU platform at the edge to enable AI/ML-accelerated real-time analysis of data collected for x-ray ptychography. Ptychography is a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Anakha V Babu , Tekin Bicer , Saugat Kandel , Tao Zhou , Daniel J. Ching , Steven Henke , Siniša Veseli , Ryan Chard , Antonino Miceli , Mathew Joseph Cherukara

Training AI foundation models has emerged as a promising large-scale learning approach for addressing real-world healthcare challenges, including digital pathology. While many of these models have been developed for tasks like disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Junlin Guo , Siqi Lu , Can Cui , Ruining Deng , Tianyuan Yao , Zhewen Tao , Yizhe Lin , Marilyn Lionts , Quan Liu , Juming Xiong , Yu Wang , Shilin Zhao , Catie Chang , Mitchell Wilkes , Mengmeng Yin , Haichun Yang , Yuankai Huo

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Generalist foundation model has ushered in newfound capabilities in medical domain. However, the contradiction between the growing demand for high-quality annotated data with patient privacy continues to intensify. The utilization of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hao Wei , Bowen Liu , Minqing Zhang , Peilun Shi , Wu Yuan

Zero-shot and prompt-based models have excelled at visual reasoning tasks by leveraging large-scale natural image corpora, but they often fail on sparse and domain-specific scientific image data. We introduce Zenesis, a no-code interactive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Shubhabrata Mukherjee , Jack Lang , Obeen Kwon , Iryna Zenyuk , Valerie Brogden , Adam Weber , Daniela Ushizima

In medical image segmentation, heterogeneous privacy policies across institutions often make joint training on pooled datasets infeasible, motivating continual image segmentation-learning from data streams without catastrophic forgetting.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Jiayi Wang , Wei Dai , Haoyu Wang , Sihan Yang , Haixia Bi , Jian Sun

Computer vision tasks require processing large amounts of data to perform image classification, segmentation, and feature extraction. Optical preprocessors can potentially reduce the number of floating point operations required by computer…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Maksym Zhelyeznuyakov , Johannes E. Fröch , Shane Colburn , Steven L. Brunton , Arka Majumdar

Purpose: Automated ultrasound image analysis is challenging due to anatomical complexity and limited annotated data. To tackle this, we take a data-centric approach, assembling the largest public ultrasound segmentation dataset and training…

Image and Video Processing · Electrical Eng. & Systems 2025-11-13 Adrien Meyer , Aditya Murali , Farahdiba Zarin , Didier Mutter , Nicolas Padoy

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

During the diagnostic process, doctors incorporate multimodal information including imaging and the medical history - and similarly medical AI development has increasingly become multimodal. In this paper we tackle a more subtle challenge:…