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We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Recent advancements in deep learning for automated image processing and classification have accelerated many new applications for medical image analysis. However, most deep learning applications have been developed using reconstructed,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Hyunkwang Lee , Chao Huang , Sehyo Yune , Shahein H. Tajmir , Myeongchan Kim , Synho Do

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

Widespread clinical deployment of computer-aided diagnosis (CAD) systems is hindered by the challenge of integrating with existing hospital IT infrastructure. Here, we introduce VisionCAD, a vision-based radiological assistance framework…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Jiaming Li , Junlei Wu , Sheng Wang , Honglin Xiong , Jiangdong Cai , Zihao Zhao , Yitao Zhu , Yuan Yin , Dinggang Shen , Qian Wang

Non-ideal measurement computed tomography (NICT) employs suboptimal imaging protocols to expand CT applications. However, the resulting trade-offs degrade image quality, limiting clinical acceptability. Although deep learning methods have…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Rongjun Ge , Yuxin Liu , Zhan Wu , Shangwen Yang , Yuan Gao , Chenyu You , Ge Wang , Shuo Li , Yuting He , Yang Chen

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Building AI models with trustworthiness is important especially in regulated areas such as healthcare. In tackling COVID-19, previous work uses convolutional neural networks as the backbone architecture, which has shown to be prone to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-20 Kai Ma , Pengcheng Xi , Karim Habashy , Ashkan Ebadi , Stéphane Tremblay , Alexander Wong

Pain is a manifold condition that impacts a significant percentage of the population. Accurate and reliable pain evaluation for the people suffering is crucial to developing effective and advanced pain management protocols. Automatic pain…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Stefanos Gkikas , Raul Fernandez Rojas , Manolis Tsiknakis

Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides exquisite soft-tissue contrast without using ionizing radiation. The clinical application of MRI may be limited by long data acquisition times; therefore, MR…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Shen Zhao , Lee C. Potter , Kiryung Lee , Rizwan Ahmad

Medical imaging analysis faces challenges such as data scarcity, high annotation costs, and privacy concerns. This paper introduces the Medical AI for Synthetic Imaging (MAISI), an innovative approach using the diffusion model to generate…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Pengfei Guo , Can Zhao , Dong Yang , Ziyue Xu , Vishwesh Nath , Yucheng Tang , Benjamin Simon , Mason Belue , Stephanie Harmon , Baris Turkbey , Daguang Xu

This paper presents a framework for automatically learning shape and appearance models for medical (and certain other) images. It is based on the idea that having a more accurate shape and appearance model leads to more accurate image…

Computer Vision and Pattern Recognition · Computer Science 2019-05-29 John Ashburner , Mikael Brudfors , Kevin Bronik , Yael Balbastre

The recent popularity of foundation models and the pre-train-and-adapt paradigm, where a large-scale model is transferred to downstream tasks, is gaining attention for volumetric medical image segmentation. However, current transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Julio Silva-Rodríguez , Jose Dolz , Ismail Ben Ayed

Model fusion seeks to combine independently trained neural networks into a single model without retraining, but is complicated by representational divergence arising from permutation invariance, random initialization, and heterogeneous…

Machine Learning · Computer Science 2026-05-29 Phoomraphee Luenam , Andreas Spanopoulos , Amit Sant , Thomas Hofmann , Sotiris Anagnostidis , Sidak Pal Singh

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Self-supervised learning (SSL) leverages vast unannotated medical datasets, yet steep technical barriers limit adoption by clinical researchers. We introduce Vision Foundry, a code-free, HIPAA-compliant platform that democratizes…

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM…

Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Adam Tupper , Christian Gagné

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Peirong Liu , Oula Puonti , Xiaoling Hu , Karthik Gopinath , Annabel Sorby-Adams , Daniel C. Alexander , W. Taylor Kimberly , Juan E. Iglesias

Deep learning has revolutionized medical image analysis, playing a vital role in modern clinical applications. However, the deployment of large-scale models in real-world clinical settings remains challenging due to high computational…

Machine Learning · Computer Science 2026-02-03 Cuong Manh Nguyen , Truong-Son Hy
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