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Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

Medical image segmentation is undergoing a paradigm shift from conventional visual pattern matching to cognitive reasoning analysis. Although Multimodal Large Language Models (MLLMs) have shown promise in integrating linguistic and visual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yuxin Xie , Yuming Chen , Yishan Yang , Yi Zhou , Tao Zhou , Zhen Zhao , Jiacheng Liu , Huazhu Fu

Referring image segmentation is a typical multi-modal task, which aims at generating a binary mask for referent described in given language expressions. Prior arts adopt a bimodal solution, taking images and languages as two modalities…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Zizhang Li , Mengmeng Wang , Jianbiao Mei , Yong Liu

The chest X-Ray (CXR) is the one of the most common clinical exam used to diagnose thoracic diseases and abnormalities. The volume of CXR scans generated daily in hospitals is huge. Therefore, an automated diagnosis system able to save the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Shuai Zhang , Xiaoyan Xin , Yang Wang , Yachong Guo , Qiuqiao Hao , Xianfeng Yang , Jun Wang , Jian Zhang , Bing Zhang , Wei Wang

Recent medical multimodal foundation models are built as multimodal LLMs (MLLMs) by connecting a CLIP-pretrained vision encoder to an LLM using LLaVA-style finetuning. This two-stage, decoupled approach introduces a projection layer that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ashwin Kumar , Robbie Holland , Corey Barrett , Jangwon Kim , Maya Varma , Zhihong Chen , Yunhe Gao , Greg Zaharchuk , Tara Taghavi , Krishnaram Kenthapadi , Akshay Chaudhari

Medical Large Vision-Language Models (Med-LVLMs) have been widely adopted for medical report generation. Despite Med-LVLMs producing state-of-the-art performance, they exhibit a bias toward predicting all findings as normal, leading to…

Multiagent Systems · Computer Science 2025-05-27 Pengyu Wang , Shuchang Ye , Usman Naseem , Jinman Kim

Large Language Models (LLMs) are increasingly adopted across domains such as education, healthcare, and finance. In healthcare, LLMs support tasks including disease diagnosis, abnormality classification, and clinical decision-making. Among…

Cryptography and Security · Computer Science 2026-03-31 Payel Bhattacharjee , Fengwei Tian , Geoffrey D. Rubin , Joseph Y. Lo , Nirav Merchant , Heidi Hanson , John Gounley , Ravi Tandon

Lung segmentation in chest X-rays (CXRs) is an important prerequisite for improving the specificity of diagnoses of cardiopulmonary diseases in a clinical decision support system. Current deep learning models for lung segmentation are…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Sivaramakrishnan Rajaraman , Feng Yang , Ghada Zamzmi , Zhiyun Xue , Sameer Antani

Accurately segmenting different organs from medical images is a critical prerequisite for computer-assisted diagnosis and intervention planning. This study proposes a deep learning-based approach for segmenting various organs from CT and…

Automated structured radiology report generation (SRRG) from chest X-ray images offers significant potential to reduce workload of radiologists by generating reports in structured formats that ensure clarity, consistency, and adherence to…

Machine Learning · Computer Science 2025-10-02 Seongjae Kang , Dong Bok Lee , Juho Jung , Dongseop Kim , Won Hwa Kim , Sunghoon Joo

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by retrieving relevant memories from an external database. However, existing RAG methods typically organize all memories in a whole database, potentially limiting…

Computation and Language · Computer Science 2024-05-28 Zheng Wang , Shu Xian Teo , Jieer Ouyang , Yongjun Xu , Wei Shi

Chest X-ray (CXR) imaging is one of the most widely used diagnostic modalities in clinical practice, encompassing a broad spectrum of diagnostic tasks. Recent advancements have seen the extensive application of reasoning-based multimodal…

Chest X-ray (CXR) radiology report generation (RRG) models have shown rapid progress on automated metrics, yet their clinical utility remains uncertain due to limited qualitative evaluation by radiologists. We present CXRMate-2, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Aaron Nicolson , Elizabeth J. Cooper , Hwan-Jin Yoon , Claire McCafferty , Ramya Krishnan , Michelle Craigie , Nivene Saad , Jason Dowling , Ian A. Scott , Bevan Koopman

Medical image segmentation is challenging due to overlapping anatomies with ambiguous boundaries and a severe imbalance between the foreground and background classes, which particularly affects the delineation of small lesions. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hao Shao , Qibin Hou

Recent transformer-based models have made significant strides in generating radiology reports from chest X-ray images. However, a prominent challenge remains: these models often lack prior knowledge, resulting in the generation of synthetic…

Computation and Language · Computer Science 2023-06-06 Sanghwan Kim , Farhad Nooralahzadeh , Morteza Rohanian , Koji Fujimoto , Mizuho Nishio , Ryo Sakamoto , Fabio Rinaldi , Michael Krauthammer

Recent advancements in artificial intelligence (AI) have precipitated significant breakthroughs in healthcare, particularly in refining diagnostic procedures. However, previous studies have often been constrained to limited functionalities.…

Artificial Intelligence · Computer Science 2024-07-08 Asma Alkhaldi , Raneem Alnajim , Layan Alabdullatef , Rawan Alyahya , Jun Chen , Deyao Zhu , Ahmed Alsinan , Mohamed Elhoseiny

Automating radiology report generation can ease the reporting workload for radiologists. However, existing works focus mainly on the chest area due to the limited availability of public datasets for other regions. Besides, they often rely…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Qi Chen , Yutong Xie , Biao Wu , Xiaomin Chen , James Ang , Minh-Son To , Xiaojun Chang , Qi Wu

Automating radiology report generation can significantly reduce the workload of radiologists and enhance the accuracy, consistency, and efficiency of clinical documentation.We propose a novel cross-modal framework that uses MedCLIP as both…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Qianhao Han , Junyi Liu , Zengchang Qin , Zheng Zheng

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Multimodal Large Language Models (MLLMs) have shown exceptional capabilities in vision-language tasks; however, effectively integrating image segmentation into these models remains a significant challenge. In this paper, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Mengcheng Lan , Chaofeng Chen , Yue Zhou , Jiaxing Xu , Yiping Ke , Xinjiang Wang , Litong Feng , Wayne Zhang