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This paper presents a new fast and robust algorithm that provides fuel-optimal impulsive control input sequences that drive a linear time-variant system to a desired state at a specified time. This algorithm is applicable to a broad class…

Optimization and Control · Mathematics 2020-10-06 Adam W. Koenig , Simone D'Amico

Proton Pump Inhibitors (PPIs) are the standard of care for gastric acid disorders but carry significant risks when administered chronically at high doses. Precise long-term control of gastric acidity is challenged by the impracticality of…

Systems and Control · Electrical Eng. & Systems 2025-07-15 Yutong Li , Ilya Kolmanovsky

In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…

In this paper, we explore the conditions for asymptotic stability of the hybrid closed-loop system resulting from the interconnection of a nonlinear plant, an intelligent sensor that generates finite-time convergent estimates of the plant…

Systems and Control · Electrical Eng. & Systems 2024-11-15 Xuanzhi Zhu , Pedro Casau , Carlos Silvestre

Conventional Artificial Intelligence (AI) systems are running into limitations in terms of training time and energy. Following the principles of the human brain, spiking neural networks trained with unsupervised learning offer a faster,…

Superconductivity · Physics 2025-04-04 Ken Segall , Leon Nichols , Will Friend , Steven B. Kaplan

This paper investigates the distributed model predictive control for an asynchronous nonlinear multi-agent system with external interference via a self-triggered generator and a prediction horizon regulator. First, a shrinking constraint…

Systems and Control · Electrical Eng. & Systems 2024-05-21 Qianqian Chen , Shaoyuan Li

The present paper deals with data-driven event-triggered control of a class of unknown discrete-time interconnected systems (a.k.a. network systems). To this end, we start by putting forth a novel distributed event-triggering transmission…

Systems and Control · Electrical Eng. & Systems 2023-09-15 Xin Wang , Jian Sun , Gang Wang , Frank Allgöwer , Jie Chen

In this work, we propose an event-triggered con- trol framework for dynamical systems with temporal logical constraints. Event-triggered control methodologies have proven to be very efficient in reducing sensing, communication and…

Robotics · Computer Science 2018-02-28 Dipankar Maity , John S. Baras

We present a thermodynamically consistent model describing the dynamics of a multi-component mixture where one enzyme component catalyzes a reaction between other components. We find that the catalytic activity alone can induce phase…

Biological Physics · Physics 2022-10-05 Matthew W. Cotton , Ramin Golestanian , Jaime Agudo-Canalejo

Self-triggered control (STC) is a well-established technique to reduce the amount of samples for sampled-data systems, and is hence particularly useful for Networked Control Systems. At each sampling instant, an STC mechanism determines not…

Systems and Control · Electrical Eng. & Systems 2021-09-15 Michael Hertneck , Frank Allgöwer

The performance of frequency regulating units for automatic generation control (AGC) of power systems depends on their ability to track the AGC signal accurately. In addition, representative models and advanced analysis and analytics can…

Systems and Control · Electrical Eng. & Systems 2022-07-12 Sarnaduti Brahma , Hamid R. Ossareh , Mads R. Almassalkhi

Several schemes for gain control are used for preventing saturation of receiver, and overloading of data processor, tracker or display in pulse radars. The use of digital processing techniques open the door to a variety of digital automatic…

Signal Processing · Electrical Eng. & Systems 2019-10-22 Sumanta Pal , Nirmala Shanmugam , Mohit Kumar , P Radhakrishna

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

We present the Alternating Direction Method of Multipliers for Performance Boosting (ADMM-PB), an approach to design performance boosting controllers for stable or pre-stabilized nonlinear systems, while explicitly seeking input and state…

Systems and Control · Electrical Eng. & Systems 2025-11-05 Gianluca Giacomelli , Danilo Saccani , Siep Weiland , Giancarlo Ferrari-Trecate , Valentina Breschi

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

Other Quantitative Biology · Quantitative Biology 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

Postprandial glucose collected through continuous glucose monitoring (CGM) provides critical information for assessing metabolic capacity and guiding dietary recommendations. Traditional approaches summarize these data into scalar measures,…

Quantitative Methods · Quantitative Biology 2026-04-03 Marcos Matabuena , Joe Sartini , Francisco Gude

Dynamical compensation (DC) provides robustness to parameter fluctuations. As an example, DC enable control of the functional mass of endocrine or neuronal tissue essential for controlling blood glucose by insulin through a nonlinear…

Systems and Control · Electrical Eng. & Systems 2024-06-04 Akram Ashyani , Yu-Heng Wu , Huan-Wei Hsu , Torbjörn E. M. Nordling

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

Machine Learning · Statistics 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

Over the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of…

Systems and Control · Electrical Eng. & Systems 2020-01-27 Mohammad Javad Khodaei , Nicholas Candelino , Amin Mehrvarz , Nader Jalili

Diabetes mellitus affects over 537 million adults worldwide. Insulin-dependent patients require continuous glucose monitoring and precise dose calculation while operating under strict power budgets on wearable devices. This paper presents…

Machine Learning · Computer Science 2026-03-31 Sahil Shrivastava