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One challenging property lurking in medical datasets is the imbalanced data distribution, where the frequency of the samples between the different classes is not balanced. Training a model on an imbalanced dataset can introduce unique…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ashkan Khakzar , Yawei Li , Yang Zhang , Mirac Sanisoglu , Seong Tae Kim , Mina Rezaei , Bernd Bischl , Nassir Navab

Banks utilize credit scoring as an important indicator of financial strength and eligibility for credit. Scoring models aim to assign statistical odds or probabilities for predicting if there is a risk of nonpayment in relation to many…

Risk Management · Quantitative Finance 2023-03-10 Oguz Koc , Omur Ugur , A. Sevtap Kestel

Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…

Quantitative Methods · Quantitative Biology 2022-10-25 Shengjia Chen , Nikunj Gupta , Woodward B. Galbraith , Valay Shah , Jacopo Cirrone

More than 144 000 Australians were diagnosed with cancer in 2019. The majority will first present to their GP symptomatically, even for cancer for which screening programs exist. Diagnosing cancer in primary care is challenging due to the…

Machine Learning · Computer Science 2020-12-21 Goce Ristanoski , Jon Emery , Javiera Martinez-Gutierrez , Damien Mccarthy , Uwe Aickelin

The identification of reliable molecular biomarkers for Parkinson's disease remains challenging due to its multifactorial nature. Although protein sequences constitute a fundamental and widely available source of biological information,…

Quantitative Methods · Quantitative Biology 2026-05-19 César Jesús Núñez-Prado , Grigori Sidorov , Liliana Chanona-Hernández

A computational challenge to validate the candidate disease genes identified in a high-throughput genomic study is to elucidate the associations between the set of candidate genes and disease phenotypes. The conventional gene set enrichment…

Genomics · Quantitative Biology 2011-02-22 TaeHyun Hwang , Wei Zhang , Maoqiang Xie , Rui Kuang

Randomized benchmarking (RB) is a widely used strategy to assess the quality of available quantum gates in a computational context. RB involves applying known random sequences of gates to an initial state and using the statistics of a final…

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Precision medicine aims to optimize treatment by identifying patient subgroups most likely to benefit from specific interventions. To support this goal, we introduce fkbma, an R package that implements a Bayesian model averaging approach…

Methodology · Statistics 2025-03-18 Lara Maleyeff , Shirin Golchi , Erica E. M. Moodie

Randomized benchmarking (RB) refers to a collection of protocols that in the past decade have become central methods for characterizing quantum gates. These protocols aim at efficiently estimating the quality of a set of quantum gates in a…

Quantum Physics · Physics 2022-06-20 Jonas Helsen , Ingo Roth , Emilio Onorati , Albert H. Werner , Jens Eisert

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…

Genomics · Quantitative Biology 2024-09-10 Kuan Yan , Yue Zeng , Dai Shi , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

In many application domains, it is important to characterize how complex learned models make their decisions across the distribution of instances. One way to do this is to identify the features and interactions among them that contribute to…

Machine Learning · Computer Science 2018-11-22 Kyubin Lee , Akshay Sood , Mark Craven

When faced with a new dataset, most practitioners begin by performing exploratory data analysis to discover interesting patterns and characteristics within data. Techniques such as association rule mining are commonly applied to uncover…

Machine Learning · Computer Science 2021-02-03 Andrew Lensen

Some response surface functions in complex engineering systems are usually highly nonlinear, unformed, and expensive-to-evaluate. To tackle this challenge, Bayesian optimization, which conducts sequential design via a posterior distribution…

Machine Learning · Statistics 2021-09-23 Areej AlBahar , Inyoung Kim , Xiaowei Yue

In recent years, machine learning has been proposed as a promising strategy to build accurate scoring functions for computational docking finalized to numerically empowered drug discovery. However, the latest studies have suggested that…

Quantitative Methods · Quantitative Biology 2023-02-17 F. Pellicani , D. Dal Ben , A. Perali , S. Pilati

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Artificial Intelligence · Computer Science 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

Fast Radio Bursts (FRBs) are millisecond-duration radio transients of extragalactic origin, exhibiting a wide range of physical and observational properties. Distinguishing between repeating and non-repeating FRBs remains a key challenge in…

Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these…