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Compressing large language models (LLMs) for deployment on commodity GPUs remains challenging: conventional scalar quantization is limited to fixed bit-widths (e.g., 8/4/3-bit), offers only a few discrete compression points, and typically…

Machine Learning · Computer Science 2026-05-07 Ye Qiao , Yian Wang , Zhiheng Chen , Hyoukjun Kwon , Sitao Huang

Hard combinatorial optimization problems, often mapped to Ising models, promise potential solutions with quantum advantage but are constrained by limited qubit counts in near-term devices. We present an innovative quantum-inspired framework…

Quantum Physics · Physics 2024-12-25 Co Tran , Quoc-Bao Tran , Hy Truong Son , Thang N Dinh

Designing compact and accurate circuits for the variational quantum eigensolver (VQE) is a central challenge in near-term quantum chemistry. Existing adaptive methods such as ADAPT-VQE design circuits by iteratively selecting operators from…

Quantum Physics · Physics 2026-05-28 Jianpeng Chen , Zirui Sheng , Cunxi Gong , Weitang Li

Vision-Language Models (VLMs) achieve outstanding performance, yet their huge model size severely hinders deployment on edge devices with limited resources. As an efficient model compression technique, vector quantization (VQ) excels in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zhong Wang , Zukang Xu , Xing Hu , Dawei Yang

Advances in hybrid bonding and packaging have driven growing interest in 3D DRAM-stacked accelerators with higher memory bandwidth and capacity. As LLMs scale to hundreds of billions or trillions of parameters, distributed inference across…

Although quantum computing holds promise for solving Combinatorial Optimization Problems (COPs), the limited qubit capacity of NISQ hardware makes large-scale instances intractable. Conventional methods attempt to bridge this gap through…

Quantum Physics · Physics 2026-01-21 Yuhan Huang , Siyuan Jin , Yichi Zhang , Qi Zhao , Jun Qi , Qiming Shao

Data scarcity remains a central challenge in materials discovery, where finding meaningful descriptors and tuning models for generalization is critical but inherently a discrete optimization problem prone to multiple local minima…

This study describes a hybrid quantum-classical computational approach for designing synthesizable deuterated $Alq_3$ emitters possessing desirable emission quantum efficiencies (QEs). This design process has been performed on the…

In recent years, there is a growing interest in using quantum computers for solving combinatorial optimization problems. In this work, we developed a generic, machine learning-based framework for mapping continuous-space inverse design…

Quantum simulators are essential tools for developing and testing quantum algorithms. However, the high-frequency traversal characteristic of quantum simulators represents an unprecedented demand in the history of IT, and existing…

Emerging Technologies · Computer Science 2025-08-22 Mingyang Yu , Haorui Yang , Donglin Wang , Desheng Kong , Ji Du , Yulong Fu , Wei Wang , Jing Xu

This technical report presents our winning contribution to the 2024 Airbus and BMW Group Quantum Computing Challenge under the category 'Quantum Solvers'. This submission addresses efficient simulation in industrial CFD using (i)…

Performance optimization is the art of continuous seeking a harmonious mapping between the application domain and hardware. Recent years have witnessed a surge of deep learning (DL) applications in industry. Conventional wisdom for…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-27 Guoping Long , Jun Yang , Wei Lin

Differential equations (DEs) serve as the cornerstone for a wide range of scientific endeavors, their solutions weaving through the core of diverse fields such as structural engineering, fluid dynamics, and financial modeling. DEs are…

Quantum Physics · Physics 2025-06-10 Josephine Hunout , Sylvain Laizet , Lorenzo Iannucci

The current era of quantum computing has yielded several algorithms that promise high computational efficiency. While the algorithms are sound in theory and can provide potentially exponential speedup, there is little guidance on how to…

Quantum Physics · Physics 2023-10-13 Ankit Kulshrestha , Danylo Lykov , Ilya Safro , Yuri Alexeev

Combinatorial optimization on near-term quantum devices is a promising path to demonstrating quantum advantage. However, the capabilities of these devices are constrained by high noise or error rates. In this paper, we propose an iterative…

Quantum Physics · Physics 2022-05-12 Xiaoyuan Liu , Anthony Angone , Ruslan Shaydulin , Ilya Safro , Yuri Alexeev , Lukasz Cincio

The emergence of quantum reinforcement learning (QRL) is propelled by advancements in quantum computing (QC) and machine learning (ML), particularly through quantum neural networks (QNN) built on variational quantum circuits (VQC). These…

Quantum Physics · Physics 2024-07-26 Samuel Yen-Chi Chen

Vector Quantization (VQ) is an appealing model compression method to obtain a tiny model with less accuracy loss. While methods to obtain better codebooks and codes under fixed clustering dimensionality have been extensively studied,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Zezhou Zhu , Yucong Zhou , Zhao Zhong

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

The computational cost of concurrent multiscale finite element methods is dominated by the repeated solution of microscopic representative volume element (RVE) problems at macroscopic quadrature points. In this work, we introduce a…

Numerical Analysis · Mathematics 2026-04-08 Yiren Wang , Michael Ortiz , Fehmi Cirak

Direct air capture (DAC) of carbon dioxide is a promising method for mitigating climate change. Solid sorbents, such as metal-organic frameworks, are currently being tested for DAC application. However, their potential for deployment at…

Quantum Physics · Physics 2024-12-05 Marco Antonio Barroca , Rodrigo Neumann Barros Ferreira , Mathias Steiner