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Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

Medical image segmentation is a crucial and time-consuming task in clinical care, where mask precision is extremely important. The Segment Anything Model (SAM) offers a promising approach, as it provides an interactive interface based on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Julien Khlaut , Elodie Ferreres , Daniel Tordjman , Hélène Philippe , Tom Boeken , Pierre Manceron , Corentin Dancette

Although new vision foundation models such as Segment Anything Model 2 (SAM2) have significantly enhanced zero-shot image segmentation capabilities, reliance on human-provided prompts poses significant challenges in adapting SAM2 to medical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yang Xing , Jiong Wu , Yuheng Bu , Kuang Gong

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

The Segment Anything Model (SAM) represents a state-of-the-art research advancement in natural image segmentation, achieving impressive results with input prompts such as points and bounding boxes. However, our evaluation and recent…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Junlong Cheng , Jin Ye , Zhongying Deng , Jianpin Chen , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Junjun He , Shaoting Zhang , Min Zhu , Yu Qiao

The Segment Anything Model 2 (SAM2) has recently demonstrated exceptional performance in zero-shot prompt segmentation for natural images and videos. However, when the propagation mechanism of SAM2 is applied to medical images, it often…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Yunhao Bai , Boxiang Yun , Zeli Chen , Qinji Yu , Yingda Xia , Yan Wang

Although SAM-based single-source domain generalization models for medical image segmentation can mitigate the impact of domain shift on the model in cross-domain scenarios, these models still face two major challenges. First, the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Huanli Zhuo , Leilei Ma , Haifeng Zhao , Shiwei Zhou , Dengdi Sun , Yanping Fu

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

The universality of deep neural networks across different modalities and their generalization capabilities to unseen domains play an essential role in medical image segmentation. The recent segment anything model (SAM) has demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Qing Xu , Jiaxuan Li , Xiangjian He , Chenxin Li , Fiseha B. Tesem , Wenting Duan , Zhen Chen , Rong Qu , Jonathan M. Garibaldi , Chang Wen Chen

The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi
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