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Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Histo-genomic multimodal survival prediction has garnered growing attention for its remarkable model performance and potential contributions to precision medicine. However, a significant challenge in clinical practice arises when only…

Machine Learning · Computer Science 2025-03-17 Fengchun Liu , Linghan Cai , Zhikang Wang , Zhiyuan Fan , Jin-gang Yu , Hao Chen , Yongbing Zhang

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

The rapid advancement of autonomous systems, including self-driving vehicles and drones, has intensified the need to forge true Spatial Intelligence from multi-modal onboard sensor data. While foundation models excel in single-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Song Wang , Lingdong Kong , Xiaolu Liu , Hao Shi , Wentong Li , Jianke Zhu , Steven C. H. Hoi

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Alzheimer's disease, a neurodegenerative disorder, is associated with neural, genetic, and proteomic factors while affecting multiple cognitive and behavioral faculties. Traditional AD prediction largely focuses on univariate disease…

In an emergency room (ER) setting, stroke triage or screening is a common challenge. A quick CT is usually done instead of MRI due to MRI's slow throughput and high cost. Clinical tests are commonly referred to during the process, but the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Tongan Cai , Haomiao Ni , Mingli Yu , Xiaolei Huang , Kelvin Wong , John Volpi , James Z. Wang , Stephen T. C. Wong

The quest for accurate prediction of drug molecule properties poses a fundamental challenge in the realm of Artificial Intelligence Drug Discovery (AIDD). An effective representation of drug molecules emerges as a pivotal component in this…

Machine Learning · Computer Science 2024-04-22 Zhuoyuan Wang , Jiacong Mi , Shan Lu , Jieyue He

Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

Many in-hospital mortality risk prediction scores dichotomize predictive variables to simplify the score calculation. However, hard thresholding in these additive stepwise scores of the form "add x points if variable v is above/below…

Machine Learning · Statistics 2015-04-30 Natalia M. Arzeno , Karla A. Lawson , Sarah V. Duzinski , Haris Vikalo

Brain stroke is a leading cause of mortality and long-term disability worldwide, underscoring the need for precise and rapid prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Md. Sabbir Hossen , Eshat Ahmed Shuvo , Shibbir Ahmed Arif , Pabon Shaha , Anichur Rahman , Md. Saiduzzaman , Fahmid Al Farid , Hezerul Abdul Karim , Abu Saleh Musa Miah

The majority of biomedical studies use limited datasets that may not generalize over large heterogeneous datasets that have been collected over several decades. The current paper develops and validates several multimodal models that can…

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

We propose SelfDoc, a task-agnostic pre-training framework for document image understanding. Because documents are multimodal and are intended for sequential reading, our framework exploits the positional, textual, and visual information of…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Peizhao Li , Jiuxiang Gu , Jason Kuen , Vlad I. Morariu , Handong Zhao , Rajiv Jain , Varun Manjunatha , Hongfu Liu

This study introduces a novel approach for early Type 2 Diabetes Mellitus (T2DM) risk prediction using a tabular transformer (TabTrans) architecture to analyze longitudinal patient data. By processing patients` longitudinal health records…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Sulaiman Khan , Md. Rafiul Biswas , Zubair Shah

This research presents a novel multimodal data fusion methodology for pain behavior recognition, integrating statistical correlation analysis with human-centered insights. Our approach introduces two key innovations: 1) integrating…

Artificial Intelligence · Computer Science 2025-01-22 Xingrui Gu , Zhixuan Wang , Irisa Jin , Zekun Wu

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Acute ischaemic stroke, caused by an interruption in blood flow to brain tissue, is a leading cause of disability and mortality worldwide. The selection of patients for the most optimal ischaemic stroke treatment is a crucial step for a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Survival analysis stands as a pivotal process in cancer treatment research, crucial for predicting patient survival rates accurately. Recent advancements in data collection techniques have paved the way for enhancing survival predictions by…

Machine Learning · Computer Science 2024-07-26 Linhao Qu , Dan Huang , Shaoting Zhang , Xiaosong Wang
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