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The placenta forms a critical barrier to infection through pregnancy, labor and, delivery. Inflammatory processes in the placenta have short-term, and long-term consequences for offspring health. Digital pathology and machine learning can…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Abhishek Sharma , Ramin Nateghi , Marina Ayad , Lee A. D. Cooper , Jeffery A. Goldstein

Grading inflammatory bowel disease (IBD) activity using standardized histopathological scoring systems remains challenging due to resource constraints and inter-observer variability. In this study, we developed a deep learning model to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Amit Das , Tanmay Shukla , Naofumi Tomita , Ryland Richards , Laura Vidis , Bing Ren , Saeed Hassanpour

As the therapeutic target for Inflammatory Bowel Disease (IBD) shifts toward histologic remission, the accurate assessment of microscopic inflammation has become increasingly central for evaluating disease activity and response to…

Despite broad application during labor and delivery, there remains considerable debate about the value of electronic fetal monitoring (EFM). EFM includes the surveillance of the fetal heart rate (FHR) patterns in conjunction with the…

Quantitative Methods · Quantitative Biology 2021-12-06 Martin G. Frasch , Shadrian B. Strong , David Nilosek , Joshua Leaverton , Barry S. Schifrin

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Cervical cancer is one of the deadliest cancers affecting women globally. Cervical intraepithelial neoplasia (CIN) assessment using histopathological examination of cervical biopsy slides is subject to interobserver variability. Automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Sudhir Sornapudi , R. Joe Stanley , William V. Stoecker , Rodney Long , Zhiyun Xue , Rosemary Zuna , Shelliane R. Frazier , Sameer Antani

Fetal growth restriction (FGR) is a prevalent pregnancy condition characterised by failure of the fetus to reach its genetically predetermined growth potential. We explore the application of model fitting techniques, linear regression…

We evaluate the performance of federated learning (FL) in developing deep learning models for analysis of digitized tissue sections. A classification application was considered as the example use case, on quantifiying the distribution of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Ujjwal Baid , Sarthak Pati , Tahsin M. Kurc , Rajarsi Gupta , Erich Bremer , Shahira Abousamra , Siddhesh P. Thakur , Joel H. Saltz , Spyridon Bakas

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Crohn's Disease (CD) and Ulcerative Colitis (UC) are the two main Inflammatory Bowel Disease (IBD) types. We developed deep learning models to identify histological disease features for both CD and UC using only endoscopic labels. We…

Prenatal ultrasound evaluates fetal growth and detects congenital abnormalities during pregnancy, but the examination of ultrasound images by radiologists requires expertise and sophisticated equipment, which would otherwise fail to improve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Yang Qi , Jiaxin Cai , Jing Lu , Runqing Xiong , Rongshang Chen , Liping Zheng , Duo Ma

Breast cancer diagnosis demands rapid and precise tools, yet traditional histopathological methods often fall short in intra-operative settings. Deep Ultraviolet (DUV) fluorescence imaging emerges as a transformative approach, offering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nagur Shareef Shaik , Teja Krishna Cherukuri , Dong Hye Ye

Purpose: Exercise-induced pulmonary hemorrhage (EIPH) is a common syndrome in sport horses with negative impact on performance. Cytology of bronchoalveolar lavage fluid by use of a scoring system is considered the most sensitive diagnostic…

Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Liyue Shen , Katie Shpanskaya , Edward Lee , Emily McKenna , Maryam Maleki , Quin Lu , Safwan Halabi , John Pauly , Kristen Yeom

Accurate analysis of the fibrosis stage plays very important roles in follow-up of patients with chronic hepatitis B infection. In this paper, a deep learning framework is presented for automatically liver fibrosis prediction. On contrary…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Jiali Liu , Wenxuan Wang , Tianyao Guan , Ningbo Zhao , Xiaoguang Han , Zhen Li

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Estimating over-amplification of human epidermal growth factor receptor 2 (HER2) on invasive breast cancer (BC) is regarded as a significant predictive and prognostic marker. We propose a novel deep reinforcement learning (DRL) based model…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Talha Qaiser , Nasir M. Rajpoot

In the pregnant mother and her fetus, chronic prenatal stress results in entrainment of the fetal heartbeat by the maternal heartbeat, quantified by the fetal stress index (FSI). Deep learning (DL) is capable of pattern detection in complex…

Quantitative Methods · Quantitative Biology 2021-12-20 Pritam Sarkar , Silvia Lobmaier , Bibiana Fabre , Diego González , Alexander Mueller , Martin G. Frasch , Marta C. Antonelli , Ali Etemad

Background: Prenatal germinal matrix-intraventricular hemorrhage (GMH-IVH) is a leading cause of infant mortality and neurodevelopmental impairment. Manual diagnosis and lesion segmentation are labor-intensive and error-prone. Deep learning…

Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdogmus , Ali Gholipour
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