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Background: Brain maturation and aging involve significant microstructural changes, resulting in functional and cognitive alterations. Quantitative MRI (qMRI) can measure this evolution, distinguishing the physiological effects of normal…

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

High-resolution diffusion tensor imaging (DTI) is beneficial for probing tissue microstructure in fine neuroanatomical structures, but long scan times and limited signal-to-noise ratio pose significant barriers to acquiring DTI at…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Chanon Ngamsombat , Yuxin Hu , Congyu Liao , Fuyixue Wang , Kawin Setsompop , Jonathan R. Polimeni , Berkin Bilgic , Susie Y. Huang

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is…

Purpose: To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Yonatan Urman , Zachary Shah , Ashwin Kumar , Bruno P. Soares , Kawin Setsompop

Understanding how the D-Wave quantum computer could be used for machine learning problems is of growing interest. Our work evaluates the feasibility of using the D-Wave as a sampler for machine learning. We describe a hybrid system that…

Quantum Physics · Physics 2020-02-03 Jennifer Sleeman , John Dorband , Milton Halem

Diffusion models (DMs) generate remarkable high quality images via the stochastic denoising process, which unfortunately incurs high sampling time. Post-quantizing the trained diffusion models in fixed bit-widths, e.g., 4 bits on weights…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Rocco Manz Maruzzelli , Basile Lewandowski , Lydia Y. Chen

Diffusion-weighted magnetic resonance imaging in brain white matter probes tissue microstructure and allows for the estimation of compartmental diffusion parameters. Recently, it became apparent that traditional single-direction diffusion…

Biological Physics · Physics 2018-09-20 Marco Reisert , Valerij G. Kiselev , Bibek Dhital

Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…

Medical Physics · Physics 2022-01-19 Qianqian Yang , David C. Reutens , Viktor Vegh

Diffusion MRI tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections. White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts.…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Alexandra J. Golby , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Diffusion magnetic resonance imaging (MRI) has revealed important insights into white matter microstructure, but its application to gray matter remains comparatively less explored. Here, we investigate whether global patterns of gray-matter…

Quantitative Methods · Quantitative Biology 2026-04-13 Lucas Z. Brito , Ryan P. Cabeen , David H. Laidlaw

Purpose: Noise in diffusion-weighted MRI (dMRI) is often spatially correlated due to different acquisition and reconstruction strategies, which is not fully accounted for in current denoising strategies. Thus, we propose a novel model-based…

Signal Processing · Electrical Eng. & Systems 2025-12-22 Vinicius P. Campos , Diego Szczupak , Tales Santini , Afonso C. Silva , Alessandro Foi , Marcelo A. C. Vieira , Corey A. Baron

White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-09-20 Hongwei Li , Gongfa Jiang , Jianguo Zhang , Ruixuan Wang , Zhaolei Wang , Wei-Shi Zheng , Bjoern Menze

This paper presents a novel deep learning-based approach named RealDiffFusionNet incorporating Neural Controlled Differential Equations (Neural CDE) - time series models that are robust in handling irregularly sampled data - and multi-head…

Machine Learning · Computer Science 2025-01-07 Aashish Cheruvu , Nathaniel Rigoni

Full waveform inversion (FWI) is a high-resolution subsurface imaging technique, but its effectiveness is limited by challenges such as noise contamination, sparse acquisition, and artifacts from multiparameter coupling. To address these…

Geophysics · Physics 2025-06-24 Feng Liu , Yaxing Li , Rui Su , Jianping Huang , Lei Bai

Magnetic Resonance Imaging (MRI) acquisitions require extensive scan times, limiting patient throughput and increasing susceptibility to motion artifacts. Accelerated parallel MRI techniques reduce acquisition time by undersampling k-space…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mingi Kang

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

The noise in diffusion-weighted images (DWIs) decreases the accuracy and precision of diffusion tensor magnetic resonance imaging (DTI) derived microstructural parameters and leads to prolonged acquisition time for achieving improved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Jonathan R. Polimeni , Berkin Bilgic , David H. Salat , Susie Y. Huang

Diffusion-weighted magnetic resonance imaging (dMRI) allows non-invasive investigation of whole-brain connectivity, which can potentially help to reveal the brain's global network architecture and abnormalities involved in neurological and…