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Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…
Due to the complexity of medical image acquisition and the difficulty of annotation, medical image datasets inevitably contain noise. Noisy data with wrong labels affects the robustness and generalization ability of deep neural networks.…
Diffusion Magnetic Resonance Imaging (dMRI) is sensitive to white matter (WM) changes across the human lifespan. Several models have been proposed to provide more specific metrics than those provided by the conventional Diffusion Tensor…
Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…
Purpose: The impact of microscopic diffusional kurtosis ($\mu K$) - arising from restricted diffusion and/or structural disorder - remains a controversial issue in contemporary diffusion MRI (dMRI). Recently, Correlation Tensor MRI (CTI)…
Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g.,…
Machine learning algorithms underpin modern diagnostic-aiding software, which has proved valuable in clinical practice, particularly in radiology. However, inaccuracies, mainly due to the limited availability of clinical samples for…
Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable image…
White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…
Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…
Diffusion MRI is a powerful tool that serves as a bridge between brain microstructure and cognition. Recent advancements in cognitive neuroscience have highlighted the persistent challenge of understanding how individual differences in…
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…
Current deep learning approaches for diffusion MRI modeling circumvent the need for densely-sampled diffusion-weighted images (DWIs) by directly predicting microstructural indices from sparsely-sampled DWIs. However, they implicitly make…
The HEALthy Brain and Childhood Development (HBCD) Study is an ongoing longitudinal initiative to understand population-level brain maturation; however, large-scale studies must overcome site-related variance and preserve biologically…
Performing magnetic resonance imaging (MRI) reconstruction from under-sampled k-space data can accelerate the procedure to acquire MRI scans and reduce patients' discomfort. The reconstruction problem is usually formulated as a denoising…
Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from…
Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…
High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…
Developing and integrating advanced image sensors with novel algorithms in camera systems are prevalent with the increasing demand for computational photography and imaging on mobile platforms. However, the lack of high-quality data for…
Biophysical diffusion MRI models like Neurite Exchange Imaging (NEXI) are essential for probing gray matter microstructure, estimating compartment diffusivities, neurite fraction, and exchange time. However, NEXI's multi-shell,…