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Detecting out-of-distribution (OOD) inputs is a central challenge for safely deploying machine learning models in the real world. Existing solutions are mainly driven by small datasets, with low resolution and very few class labels (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Rui Huang , Yixuan Li

Motivation: Deep learning models deployed for use on medical tasks can be equipped with Out-of-Distribution Detection (OoDD) methods in order to avoid erroneous predictions. However it is unclear which OoDD method should be used in…

Machine Learning · Computer Science 2020-08-06 Tianshi Cao , Chin-Wei Huang , David Yu-Tung Hui , Joseph Paul Cohen

Deep neural networks achieve superior performance in challenging tasks such as image classification. However, deep classifiers tend to incorrectly classify out-of-distribution (OOD) inputs, which are inputs that do not belong to the…

Machine Learning · Computer Science 2019-10-24 Vahdat Abdelzad , Krzysztof Czarnecki , Rick Salay , Taylor Denounden , Sachin Vernekar , Buu Phan

Deep neural networks (DNNs) for the semantic segmentation of images are usually trained to operate on a predefined closed set of object classes. This is in contrast to the "open world" setting where DNNs are envisioned to be deployed to.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Robin Chan , Matthias Rottmann , Hanno Gottschalk

Density-based Out-of-distribution (OOD) detection has recently been shown unreliable for the task of detecting OOD images. Various density ratio based approaches achieve good empirical performance, however methods typically lack a…

Machine Learning · Statistics 2022-06-09 Mingtian Zhang , Andi Zhang , Tim Z. Xiao , Yitong Sun , Steven McDonagh

When deployed for risk-sensitive tasks, deep neural networks must be able to detect instances with labels from outside the distribution for which they were trained. In this paper we present a novel framework to benchmark the ability of…

Machine Learning · Computer Science 2023-02-24 Ido Galil , Mohammed Dabbah , Ran El-Yaniv

We present our novel deep multi-task learning method for medical image segmentation. Existing multi-task methods demand ground truth annotations for both the primary and auxiliary tasks. Contrary to it, we propose to generate the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Binod Bhattarai , Ronast Subedi , Rebati Raman Gaire , Eduard Vazquez , Danail Stoyanov

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Effective Out-of-Distribution (OOD) detection is criti-cal for ensuring the reliability of semantic segmentation models, particularly in complex road environments where safety and accuracy are paramount. Despite recent advancements in large…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Jeonghyo Song , Kimin Yun , DaeUng Jo , Jinyoung Kim , Youngjoon Yoo

High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Anghong Du , Nay Aung , Theodoros N. Arvanitis , Stefan K. Piechnik , Joao A C Lima , Steffen E. Petersen , Le Zhang

Out-of-distribution (OOD) detection is committed to delineating the classification boundaries between in-distribution (ID) and OOD images. Recent advances in vision-language models (VLMs) have demonstrated remarkable OOD detection…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Zhixia He , Chen Zhao , Minglai Shao , Xintao Wu , Xujiang Zhao , Dong Li , Qin Tian , Linlin Yu

A central challenge for the task of semantic segmentation is the prohibitive cost of obtaining dense pixel-level annotations to supervise model training. In this work, we show that in order to achieve a good level of segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-04-16 Gyungin Shin , Weidi Xie , Samuel Albanie

Research around Spiking Neural Networks has ignited during the last years due to their advantages when compared to traditional neural networks, including their efficient processing and inherent ability to model complex temporal dynamics.…

Neural and Evolutionary Computing · Computer Science 2022-10-04 Aitor Martinez Seras , Javier Del Ser , Jesus L. Lobo , Pablo Garcia-Bringas , Nikola Kasabov

In this work, we train a network to simultaneously perform segmentation and pixel-wise Out-of-Distribution (OoD) detection, such that the segmentation of unknown regions of scenes can be rejected. This is made possible by leveraging an OoD…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 David Williams , Matthew Gadd , Daniele De Martini , Paul Newman

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu

Recent years have witnessed a rapid development of automated methods for skin lesion diagnosis and classification. Due to an increasing deployment of such systems in clinics, it has become important to develop a more robust system towards…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Deval Mehta , Yaniv Gal , Adrian Bowling , Paul Bonnington , Zongyuan Ge

Current deep learning-based approaches for the segmentation of microscopy images heavily rely on large amount of training data with dense annotation, which is highly costly and laborious in practice. Compared to full annotation where the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-11 Shijie Li , Mengwei Ren , Thomas Ach , Guido Gerig

Recent advancements have explored text-to-image diffusion models for synthesizing out-of-distribution (OOD) samples, substantially enhancing the performance of OOD detection. However, existing approaches typically rely on perturbing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Xin Gao , Jiyao Liu , Guanghao Li , Yueming Lyu , Jianxiong Gao , Weichen Yu , Ningsheng Xu , Liang Wang , Caifeng Shan , Ziwei Liu , Chenyang Si

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding

Deep learning techniques for 3D brain vessel image segmentation have not been as successful as in the segmentation of other organs and tissues. This can be explained by two factors. First, deep learning techniques tend to show poor…

Computer Vision and Pattern Recognition · Computer Science 2021-11-04 Vien Ngoc Dang , Francesco Galati , Rosa Cortese , Giuseppe Di Giacomo , Viola Marconetto , Prateek Mathur , Karim Lekadir , Marco Lorenzi , Ferran Prados , Maria A. Zuluaga