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Time-dependent driving influences the quantum and thermodynamic fluctuations of a system, changing the familiar physical picture of electronic noise which is an important source of information the about microscopic mechanism of quantum…

Mesoscale and Nanoscale Physics · Physics 2020-11-25 Thomas D. Honeychurch , Daniel S. Kosov

Detecting brief changes in time-series data remains a major challenge in fields where short-lived states carry meaning. In single-molecule localisation microscopy, this problem is particularly acute as fluorescent molecules used to tag…

Methodology · Statistics 2026-03-25 Emily Gribbin , Benjamin Davis , Daniel Rolfe , Hannah Mitchell

The theory of stochastic processes impacts both physical and social sciences. At the molecular scale, stochastic dynamics is ubiquitous because of thermal fluctuations. The Fokker-Plank-Smoluchowski equation models the time evolution of the…

Modeling the timing performance of light-based radiation detectors accurately is essential for optimizing time-of-flight positron emission tomography (TOF-PET). We present an analytic framework that combines existing models to predict the…

Instrumentation and Detectors · Physics 2025-10-08 Nicolaus Kratochwil , Emilie Roncali , Gerard Arino-Estrada

Optical imaging of genetically encoded calcium indicators is a powerful tool to record the activity of a large number of neurons simultaneously over a long period of time from freely behaving animals. However, determining the exact time at…

Applications · Statistics 2021-03-08 Tong Shen , Kevin Johnston , Gyorgy Lur , Michele Guindani , Hernando Ombao , Zhaoxia Yu

Circulating blood cell clusters (CCCs) containing red blood cells (RBCs), white blood cells(WBCs), and platelets are significant biomarkers linked to conditions like thrombosis, infection, and inflammation. Flow cytometry, paired with…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Suqiang Ma , Subhadeep Sengupta , Yao Lee , Beikang Gu , Xianyan Chen , Xianqiao Wang , Yang Liu , Mengjia Xu , Galit H. Frydman , He Li

One of the most striking findings in modern research on large language models (LLMs) is that scaling up compute during training leads to better results. However, less attention has been given to the benefits of scaling compute during…

Computation and Language · Computer Science 2024-11-21 Sean Welleck , Amanda Bertsch , Matthew Finlayson , Hailey Schoelkopf , Alex Xie , Graham Neubig , Ilia Kulikov , Zaid Harchaoui

Diffusion Large Language Models (DLLMs) offer a compelling alternative to Auto-Regressive models, but their deployment is constrained by high decoding cost. In this work, we identify a key inefficiency in DLLM decoding: while computation is…

Machine Learning · Computer Science 2026-02-02 Kaihua Liang , Xin Tan , An Zhong , Hong Xu , Marco Canini

Time series foundation models (TSFMs) have recently gained significant attention due to their strong zero-shot capabilities and widespread real-world applications. Such models typically require a computationally costly pre-training on…

Particle flow filters solve Bayesian inference problems by smoothly transforming a set of particles into samples from the posterior distribution. Particles move in state space under the flow of an McKean-Vlasov-Ito process. This work…

Optimization and Control · Mathematics 2025-05-02 Amit N Subrahmanya , Andrey A Popov , Adrian Sandu

Estimating the covariance structure of multivariate time series is a fundamental problem with a wide-range of real-world applications -- from financial modeling to fMRI analysis. Despite significant recent advances, current state-of-the-art…

Machine Learning · Computer Science 2021-02-12 Hrayr Harutyunyan , Daniel Moyer , Hrant Khachatrian , Greg Ver Steeg , Aram Galstyan

Motivation: Flow Injection Analysis coupled to High-Resolution Mass Spectrometry (FIA-HRMS) is a promising approach for high-throughput metabolomics. FIA-HRMS data, however, cannot be preprocessed with current software tools which rely on…

Quantitative Methods · Quantitative Biology 2017-08-15 Alexis Delabrière , Ulli Hohenester , Benoit Colsch , Christophe Junot , François Fenaille , Etienne Thévenot

The increasing risk of epidemics and a fast-growing world population has contributed to a great investment in phylogenetic analysis, in order to track numerous diseases and conceive effective medication and treatments. Phylogenetic analysis…

Social and Information Networks · Computer Science 2022-11-29 Miguel Luis , Catia Vaz

When the complete understanding of a complex system is not available, as, e.g., for systems considered in the real-world, we need a top-down approach to complexity. In this approach one may start with the desire to understand general…

Statistical Mechanics · Physics 2019-05-22 Joachim Peinke , Mohammad Reza Rahimi Tabar , Matthias Wächter

Although pre-trained transformers and reprogrammed text-based LLMs have shown strong performance on time series tasks, the best-performing architectures vary widely across tasks, with most models narrowly focused on specific areas, such as…

Machine Learning · Computer Science 2024-11-27 Shanghua Gao , Teddy Koker , Owen Queen , Thomas Hartvigsen , Theodoros Tsiligkaridis , Marinka Zitnik

Recent top-performing temporal 3D detectors based on Lidars have increasingly adopted region-based paradigms. They first generate coarse proposals, followed by encoding and fusing regional features. However, indiscriminate sampling and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Chenxu Dang , Zaipeng Duan , Pei An , Xinmin Zhang , Xuzhong Hu , Jie Ma

In a system of many similar self-propelled entities such as flocks of birds, fish school, cells and molecules, the interactions with neighbors can lead to a "coherent state", meaning the formation of visually compelling aggregation patterns…

Applications · Statistics 2024-03-07 Thevasha Sathiyakumar , Shantanu Sur , Sumona Mondal , Marko Budišić

We present FlowLM, a flow matching language model transformed from pre-trained diffusion language models via efficient fine-tuning. By re-aligning the curved sampling trajectories of diffusion models into straight-line flows, FlowLM enables…

Computation and Language · Computer Science 2026-05-21 Runzhe Zhang , Letian Chen , Wenpeng Zhang , Zhouhan Lin , Peilin Zhao

Time-to-Digital Converters (TDCs) are a crucial tool in a wide array of fields, in particular for quantum communication, where time taggers performance can severely affect the quality of the entire application. Nowadays, FPGA-based TDCs…

Signal Processing · Electrical Eng. & Systems 2026-02-26 Matías Rubén Bolaños , Daniele Vogrig , Paolo Villoresi , Giuseppe Vallone , Andrea Stanco