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Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

We develop a physics-informed neural network (PINN) to significantly augment state-of-the-art experimental data and apply it to stratified flows. The PINN is a fully-connected deep neural network fed with time-resolved, three-component…

Fluid Dynamics · Physics 2023-09-27 Lu Zhu , Xianyang Jiang , Adrien Lefauve , Rich R. Kerswell , P. F. Linden

Physics-Informed Neural Networks (PINNs) provide a learning-based framework for solving partial differential equations (PDEs) by embedding governing physical laws into neural network training. In practice, however, their performance is…

Machine Learning · Computer Science 2026-01-21 Pancheng Niu , Jun Guo , Qiaolin He , Yongming Chen , Yanchao Shi

The present work investigates the use of physics-informed neural networks (PINNs) for the 3D reconstruction of unsteady gravity currents from limited data. In the PINN context, the flow fields are reconstructed by training a neural network…

Fluid Dynamics · Physics 2023-06-16 Mickaël Delcey , Yoann Cheny , Sébastien Kiesgen de Richter

Physics-Informed Neural Networks (PINNs) have revolutionized solving differential equations by integrating physical laws into neural networks training. This paper explores PINNs for open-loop optimal control problems (OCPs) with incomplete…

Optimization and Control · Mathematics 2025-01-27 Alessandro Alla , Giulia Bertaglia , Elisa Calzola

The solution of partial differential equations (PDES) on irregular domains has long been a subject of significant research interest. In this work, we present an approach utilizing physics-informed neural networks (PINNs) to achieve…

Computational Physics · Physics 2025-06-12 Cuizhi Zhou , Kaien Zhu

Parameter estimation remains a challenging task across many areas of engineering. Because data acquisition can often be costly, limited, or prone to inaccuracies (noise, uncertainty) it is crucial to identify sensor configurations that…

Machine Learning · Statistics 2025-11-20 Georgios Venianakis , Constantinos Theodoropoulos , Michail Kavousanakis

Physics-informed neural networks (PINNs) have proven to be a promising method for the rapid solving of partial differential equations (PDEs) in both forward and inverse problems. However, due to the smoothness assumption of functions…

Computational Physics · Physics 2026-03-25 Guoqiang Lei , D. Exposito , Xuerui Mao

Physics-informed neural networks (PINNs) have received significant attention as a unified framework for forward, inverse, and surrogate modeling of problems governed by partial differential equations (PDEs). Training PINNs for forward…

Machine Learning · Computer Science 2022-06-22 Ehsan Haghighat , Danial Amini , Ruben Juanes

Physics-Informed Neural Network (PINN) is a novel multi-task learning framework useful for solving physical problems modeled using differential equations (DEs) by integrating the knowledge of physics and known constraints into the…

Machine Learning · Computer Science 2024-09-18 Shivprasad Kathane , Shyamprasad Karagadde

Physics-informed neural networks (PINNs) have recently received much attention due to their capabilities in solving both forward and inverse problems. For training a deep neural network associated with a PINN, one typically constructs a…

Machine Learning · Computer Science 2022-08-26 Pouyan Nasiri , Roozbeh Dargazany

Physics-informed neural networks (PINNs) are an increasingly powerful way to solve partial differential equations, generate digital twins, and create neural surrogates of physical models. In this manuscript we detail the inner workings of…

The current work aims to incorporate physics-based loss in Physics Informed Neural Network (PINN) directly using the numerical residual obtained from the governing equation in any dicretized forward solver. PINN's major difficulties in…

Numerical Analysis · Mathematics 2025-09-30 Rahul Halder , Giovanni Stabile , Gianluigi Rozza

Motivated by recent research on Physics-Informed Neural Networks (PINNs), we make the first attempt to introduce the PINNs for numerical simulation of the elliptic Partial Differential Equations (PDEs) on 3D manifolds. PINNs are one of the…

Numerical Analysis · Mathematics 2021-03-05 Zhuochao Tang , Zhuojia Fu

Recent advancements in physics-informed neural networks (PINNs) and their variants have garnered substantial focus from researchers due to their effectiveness in solving both forward and inverse problems governed by differential equations.…

Machine Learning · Computer Science 2026-01-06 Shivani Saini , Ramesh Kumar Vats , Arup Kumar Sahoo

In this paper, we propose a novel Physics-Informed Neural Network (PINN) framework based on the Cord\`{e}s condition for solving both linear and fully nonlinear partial differential equations (PDEs) in non-divergence form, together with…

Numerical Analysis · Mathematics 2026-04-29 Bingcheng Hu , Lixiang Jin , Zhaoxiang Li

We discuss nonlinear model predictive control (NMPC) for multi-body dynamics via physics-informed machine learning methods. Physics-informed neural networks (PINNs) are a promising tool to approximate (partial) differential equations. PINNs…

Optimization and Control · Mathematics 2021-09-23 Jonas Nicodemus , Jonas Kneifl , Jörg Fehr , Benjamin Unger

Physics-informed neural networks (PINNs) and their variants have been very popular in recent years as algorithms for the numerical simulation of both forward and inverse problems for partial differential equations. This article aims to…

Numerical Analysis · Mathematics 2024-11-20 Tim De Ryck , Siddhartha Mishra

Physics-Informed Neural Networks (PINNs) have emerged as a powerful tool for integrating physics-based constraints and data to address forward and inverse problems in machine learning. Despite their potential, the implementation of PINNs…

Optimization and Control · Mathematics 2024-12-19 Alan Williams , Christopher Leon , Alexander Scheinker

Physics-Informed Neural Networks (PINNs) are effective methods for solving inverse problems and discovering governing equations from observational data. However, their performance degrades significantly under complex measurement noise and…

Machine Learning · Computer Science 2026-02-04 Hankyeol Kim , Pilsung Kang