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Collective motion is an ubiquitous phenomenon in nature, inspiring engineers, physicists and mathematicians to develop mathematical models and bio-inspired designs. Collective motion at small to medium group sizes ($\sim$10-1000…

Machine Learning · Computer Science 2024-01-19 Utkarsh Pratiush , Arshed Nabeel , Vishwesha Guttal , Prathosh AP

Traditional approaches to ecosystem modelling have relied on spatially homogeneous approximations to interaction, growth and death. More recently, spatial interaction and dispersal have also been considered. While these leads to certain…

Populations and Evolution · Quantitative Biology 2010-10-07 Thomas Adams \ast , Graeme Ackland , Glenn Marion , Colin Edwards

The modelling of human crowd behaviors offers many challenging questions to science in general. Specifically, the social human behavior consists of many physiological and psychological processes which are still largely unknown. To model…

Physics and Society · Physics 2023-10-17 Thi Kim Thoa Thieu , Roderick Melnik

In many biological systems, motile agents exhibit random motion with short-term directional persistence, together with crowding effects arising from spatial exclusion. We formulate and study a class of lattice-based models for multiple…

Biological Physics · Physics 2019-11-06 Stephen Zhang , Aaron Chong , Barry D. Hughes

This work proposes stochastic partial differential equations (SPDEs) as a practical tool to replicate clustering effects of more detailed particle-based dynamics. Inspired by membrane-mediated receptor dynamics on cell surfaces, we…

Quantitative Methods · Quantitative Biology 2025-01-22 Nathalie Wehlitz , Mohsen Sadeghi , Alberto Montefusco , Christof Schütte , Grigorios A. Pavliotis , Stefanie Winkelmann

We adapt a fitness function from evolutionary game theory as a mechanism for aggregation and dispersal in a partial differential equation (PDE) model of two interacting populations, described by density functions $u$ and $v$. We consider a…

Populations and Evolution · Quantitative Biology 2018-03-16 Russ deForest , Andrew Belmonte

The proposed stochastic model for pedestrian dynamics is based on existing approaches using cellular automata, combined with substantial extensions, to compensate the deficiencies resulting of the discrete grid structure. This agent motion…

Physics and Society · Physics 2021-04-01 Michael Schultz

The question of whether biological populations survive or are eventually driven to extinction has long been examined using mathematical models. In this work we study population survival or extinction using a stochastic, discrete…

Populations and Evolution · Quantitative Biology 2021-09-15 Yifei Li , Stuart T. Johnston , Pascal R. Buenzli , Peter van Heijster , Matthew J. Simpson

Lattice-based random walk models are widely used to study populations of migrating cells with motility bias and proliferation. Crowding is typically represented by volume exclusion, where each lattice site can be occupied by at most one…

Populations and Evolution · Quantitative Biology 2026-01-28 Michael J. Plank , Matthew J. Simpson

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Regulation of cell growth and division is essential to achieve cell-size homeostasis. Recent advances in imaging technologies, such as ``mother machines" for bacteria or yeast, have allowed long-term tracking of cell-size dynamics across…

Quantitative Methods · Quantitative Biology 2024-08-28 Shijie Zhang , Chenyi Fei , Jörn Dunkel

Nonlocal aggregation-diffusion models, when coupled with a spatial map, can capture cognitive and memory-based influences on animal movement and population-level patterns. In this work, we study a one-dimensional…

Analysis of PDEs · Mathematics 2025-03-17 Yurij Salmaniw , Di Liu , Junping Shi , Hao Wang

Autoregressive next-step prediction models have become the de-facto standard for building data-driven neural solvers to forecast time-dependent partial differential equations (PDEs). Denoise training that is closely related to diffusion…

Machine Learning · Computer Science 2025-03-31 Zijie Li , Anthony Zhou , Amir Barati Farimani

Simulation of stochastic spatially-extended systems is a challenging problem. The fundamental quantities in these models are individual entities such as molecules, cells, or animals, which move and react in a random manner. In big systems,…

Quantitative Methods · Quantitative Biology 2024-09-24 Tomás Alarcón , Natalia Briñas-Pascual , Juan Calvo , Pilar Guerrero , Daria Stepanova

Stochastic models of diffusion with excluded-volume effects are used to model many biological and physical systems at a discrete level. The average properties of the population may be described by a continuum model based on partial…

Chemical Physics · Physics 2012-12-20 Maria Bruna , S. Jonathan Chapman

Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different…

Dynamical Systems · Mathematics 2022-07-27 Maria-Veronica Ciocanel

We investigate predator-prey school interactions in aquatic environments using a stochastic differential equation (SDE)-based, particle-level model that incorporates attraction, repulsion, alignment, and environmental noise. Two predation…

Populations and Evolution · Quantitative Biology 2025-10-13 Junyi Qi , Ton Viet Ta

Numerous processes across both the physical and biological sciences are driven by diffusion. Partial differential equations (PDEs) are a popular tool for modelling such phenomena deterministically, but it is often necessary to use…

Quantitative Methods · Quantitative Biology 2016-05-25 Paul R. Taylor , Ruth E. Baker , Matthew J. Simpson , Christian A. Yates

Pedestrian trajectory prediction is essential for collision avoidance in autonomous driving and robot navigation. However, predicting a pedestrian's trajectory in crowded environments is non-trivial as it is influenced by other pedestrians'…

Computer Vision and Pattern Recognition · Computer Science 2019-02-15 Sirin Haddad , Meiqing Wu , He Wei , Siew Kei Lam

Many imaging techniques for biological systems -- like fixation of cells coupled with fluorescence microscopy -- provide sharp spatial resolution in reporting locations of individuals at a single moment in time but also destroy the dynamics…

Subcellular Processes · Quantitative Biology 2024-05-15 Christopher E. Miles , Scott A. McKinley , Fangyuan Ding , Richard B. Lehoucq