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The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Understanding neurocognitive computations will require not just localizing cognitive information distributed throughout the brain but also determining how that information got there. We review recent advances in linking empirical and…

Neurons and Cognition · Quantitative Biology 2019-10-22 Takuya Ito , Luke Hearne , Ravi Mill , Carrisa Cocuzza , Michael W. Cole

Recurrent cortical networks provide reservoirs of states that are thought to play a crucial role for sequential information processing in the brain. However, classical reservoir computing requires manual adjustments of global network…

Neurons and Cognition · Quantitative Biology 2021-04-02 Fabian Schubert , Claudius Gros

Recent \emph{in vivo} experiments have illustrated the importance of understanding the hemodynamics of heart morphogenesis. In particular, ventricular trabeculation is governed by a delicate interaction between hemodynamic forces,…

Tissues and Organs · Quantitative Biology 2018-09-19 Nicholas A. Battista , Andrea N. Lane , Jiandong Liu , Laura A. Miller

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…

Numerical Analysis · Mathematics 2022-01-06 Beatrice Ghitti , Eleuterio F. Toro , Lucas O. Müller

Mathematical models for physiological processes aid qualitative understanding of the impact of various parameters on the underlying process. We analyse two such models for human physiological processes: the Mackey-Glass and the Lasota…

Systems and Control · Computer Science 2018-10-12 Sreelakshmi Manjunath , Gopal Krishna Kamath , Gaurav Raina

Computer modeling can provide quantitative insight into cardiac fluid dynamics phenomena that are not evident from standard imaging tools. We propose a new approach to modeling left ventricle fluid dynamics based on an image-driven…

Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…

Non-stationarity is the rule in the atmospheric boundary layer (ABL). Under such conditions, the flow may experience departures from equilibrium with the underlying surface stress, misalignment of shear stresses and strain rates, and…

Fluid Dynamics · Physics 2023-07-27 Weiyi Li , Marco G. Giometto

Controlling the flow and routing of data is a fundamental problem in many distributed networks, including transportation systems, integrated circuits, and the Internet. In the brain, synaptic plasticity rules have been discovered that…

Neural and Evolutionary Computing · Computer Science 2017-04-18 Jonathan Y. Suen , Saket Navlakha

This PhD thesis develops an integrated mathematical model for autonomic nervous system control on cardiovascular activity. The model extensively covers cardiovascular neural pathways including a wide range of afferent sensory neurons,…

Tissues and Organs · Quantitative Biology 2019-01-18 Michel Kana

The work is devoted to the development and computational implementation of the homogenization method for modeling unsteady flows of a viscous incompressible fluid in periodic porous media taking into account memory effects. At the…

Numerical Analysis · Mathematics 2026-04-29 P. N. Vabishchevich

Computational modeling is becoming a widely used methodology in modern neuroscience. However, as the complexity of the phenomena under study increases, the analysis of the results emerging from the simulations concomitantly becomes more…

Neurons and Cognition · Quantitative Biology 2020-03-16 Sergio E. Galindo , Pablo Toharia , Oscar D. Robles , Eduardo Ros , Luis Pastor , Jesús A. Garrido

The CVS is composed of numerous interacting and dynamically regulated physiological subsystems which each generate measurable periodic components such that the CVS can itself be presented as a system of weakly coupled oscillators. The…

Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…

Soft Condensed Matter · Physics 2011-09-16 Florian Janoschek , Federico Toschi , Jens Harting

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

Computational Engineering, Finance, and Science · Computer Science 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

When an external field drives a colloidal system out of equilibrium, the ensuing colloidal response can be very complex and obtaining a detailed physical understanding often requires case-by-case considerations. In order to facilitate…

Soft Condensed Matter · Physics 2019-02-13 Daniel de las Heras , Johannes Renner , Matthias Schmidt

Numerical models are increasingly used for non-invasive diagnosis and treatment planning in coronary artery disease, where service-based technologies have proven successful in identifying hemodynamically significant and hence potentially…

Medical Physics · Physics 2020-05-01 Jongmin Seo , Casey Fleeter , Andrew M. Kahn , Alison L. Marsden , Daniele E. Schiavazzi

Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of a few macroscopic parameters. However, such hydrodynamic parameters are difficult to derive from microscopics. Seldom is this challenge more…