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Hybrid quantum mechanical-molecular mechanical (QM/MM) simulations are widely used in enzyme simulation. Over ten convergence studies of QM/MM methods have revealed over the past several years that key energetic and structural properties…

Chemical Physics · Physics 2017-01-11 Maria Karelina , Heather J. Kulik

Unfitted finite element methods, like CutFEM, have traditionally been implemented in a matrix-based fashion, where a sparse matrix is assembled and later applied to vectors while solving the resulting linear system. With the goal of…

Numerical Analysis · Mathematics 2024-04-15 Maximilian Bergbauer , Peter Munch , Wolfgang A. Wall , Martin Kronbichler

In this paper, we propose a hybrid method that combines finite element method (FEM) and physics-informed neural network (PINN) for solving linear elliptic problems. This method contains three steps: (1) train a PINN and obtain an…

Numerical Analysis · Mathematics 2025-03-20 Xiao Chen , Yixin Luo , Jingrun Chen

Quantum computing has emerged as a promising platform for simulating strongly correlated systems in chemistry, for which the standard quantum chemistry methods are either qualitatively inaccurate or too expensive. However, due to the…

Chemical Physics · Physics 2024-05-06 Max Rossmannek , Fabijan Pavošević , Angel Rubio , Ivano Tavernelli

We analyse and implement a quasi-Monte Carlo (QMC) finite element method (FEM) for the forward problem of uncertainty quantification (UQ) for the Helmholtz equation with random coefficients, both in the second-order and zero-order terms of…

Numerical Analysis · Mathematics 2025-11-04 Ivan G. Graham , Frances Y. Kuo , Dirk Nuyens , Ian H. Sloan , Euan A. Spence

Motivated by problems where the response is needed at select localized regions in a large computational domain, we devise a novel finite element discretization that results in exponential convergence at pre-selected points. The two key…

Numerical Analysis · Mathematics 2016-08-03 Murthy N. Guddati , Vladimir Druskin , Ali Vaziri Astaneh

This paper presents a novel approach for solving fourth-order phase-field models in brittle fracture mechanics using the Interior Penalty Finite Element Method (IP-FEM). The fourth-order model improves numerical stability and accuracy…

Numerical Analysis · Mathematics 2025-04-15 Tian Tian , Chen Chunyu , Wei Huayi

Homogenization in terms of multiscale limits transforms a multiscale problem with $n+1$ asymptotically separated microscales posed on a physical domain $D \subset \mathbb{R}^d$ into a one-scale problem posed on a product domain of dimension…

Numerical Analysis · Mathematics 2020-06-03 V. Kazeev , I. Oseledets , M. Rakhuba , Ch. Schwab

This paper analyses the finite element component of the error when using preintegration to approximate the cdf and pdf for uncertainty quantification (UQ) problems involving elliptic PDEs with random inputs. It is a follow up to Gilbert,…

Numerical Analysis · Mathematics 2025-10-28 Alexander D. Gilbert

The solution of large sparse linear systems via factorization methods such as LU or Cholesky decomposition, can be computationally expensive due to the introduction of non-zero elements, or ``fill-in.'' Graph partitioning can be used to…

This paper presents a novel methodology for fast simulation and analysis of transient heat transfer. The proposed methodology is suitable for real-time applications owing to (i) establishing the solution method from the viewpoint of…

Computational Engineering, Finance, and Science · Computer Science 2021-12-30 Jinao Zhang , Sunita Chauhan

A multiscale QM/classical approach is presented, that is able to model the optical properties of complex nanostructures composed of a molecular system adsorbed on metal nanoparticles. The latter are described by a combined…

Chemical Physics · Physics 2024-10-29 Pablo Grobas Illobre , Piero Lafiosca , Luca Bonatti , Tommaso Giovannini , Chiara Cappelli

The aggregated unfitted finite element method (AgFEM) is a methodology recently introduced in order to address conditioning and stability problems associated with embedded, unfitted, or extended finite element methods. The method is based…

Numerical Analysis · Computer Science 2019-08-20 Francesc Verdugo , Alberto F. Martín , Santiago Badia

The Intrinsic Surface Finite Element Method (ISFEM) was recently proposed to solve Partial Differential Equations (PDEs) on surfaces. ISFEM proceeds by writing the PDE with respect to a local coordinate system anchored to the surface and…

Numerical Analysis · Mathematics 2024-10-08 Elena Bachini , Mario Putti

We describe and evaluate a numerical solution strategy for simulating surface acoustic waves through semiconductor devices with complex geometries. This multi-physics problem is of particular relevance to the design of quantum electronic…

Computational Physics · Physics 2007-05-23 S. Rahman , H. P. Langtangen , C. H. W. Barnes

Quantum machine learning (QML) has emerged as an important area for Quantum applications, although useful QML applications would require many qubits. Therefore our paper is aimed at exploring the successful application of the Quantum…

Quantum Physics · Physics 2020-12-15 Jae-Eun Park , Brian Quanz , Steve Wood , Heather Higgins , Ray Harishankar

Solving large-scale sparse linear systems is a challenging computational task due to the introduction of non-zero elements, or "fill-in." The Graph Partitioning Problem (GPP) arises naturally when minimizing fill-in and accelerating…

Simulating quantum dynamics is expected to be performed more easily on a quantum computer than on a classical computer. However, the currently available quantum devices lack the capability to implement fault-tolerant quantum algorithms for…

Quantum Physics · Physics 2022-02-28 Kian Hwee Lim , Tobias Haug , Leong Chuan Kwek , Kishor Bharti

An accurate, physically-based, and differentiable model of soft robots can unlock downstream applications in optimal control. The Finite Element Method (FEM) is an expressive approach for modeling highly deformable structures such as…

Robotics · Computer Science 2022-03-01 Mathieu Dubied , Mike Michelis , Andrew Spielberg , Robert Katzschmann

The variational quantum eigensolver (VQE) is a hybrid quantum-classical algorithm designed for current and near-term quantum devices. Despite its initial success, there is a lack of understanding involving several of its key aspects. There…

Quantum Physics · Physics 2023-03-22 Manpreet Singh Jattana , Fengping Jin , Hans De Raedt , Kristel Michielsen