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Learning from Preferences in Reinforcement Learning (PbRL) has gained attention recently, as it serves as a natural fit for complicated tasks where the reward function is not easily available. However, preferences often come with…

Machine Learning · Computer Science 2026-03-19 Yuxuan Li , Harshith Reddy Kethireddy , Srijita Das

When data on treatment assignment, outcomes, and covariates from a randomized trial are available, a question of interest is to what extent covariates can be used to optimize treatment decisions. Statistical hypothesis testing of…

Applications · Statistics 2020-02-04 Mohsen Sadatsafavi , Mohammad Ali Mansournia , Paul Gustafson

Clinical study populations often differ meaningfully from the broader populations to which results are intended to generalize. Weighting methods such as inverse probability of sampling weights (IPSW) reweight study participants to resemble…

Methodology · Statistics 2025-12-02 William Stewart , Carly L. Brantner , Elizabeth A. Stuart , Laine Thomas

A growing statistical literature focuses on causal inference in the context of experiments where the target of inference is the average treatment effect in a finite population and random assignment determines which subjects are allocated to…

Methodology · Statistics 2025-09-04 Jonas M. Mikhaeil , Donald P. Green

Reinforcement learning with human feedback for aligning large language models (LLMs) trains a reward model typically using ranking loss with comparison pairs.However, the training procedure suffers from an inherent problem: the uncontrolled…

Computation and Language · Computer Science 2024-09-19 Hang Zhou , Chenglong Wang , Yimin Hu , Tong Xiao , Chunliang Zhang , Jingbo Zhu

Reinforcement Learning from Human Feedback (RLHF) has recently surged in popularity, particularly for aligning large language models and other AI systems with human intentions. At its core, RLHF can be viewed as a specialized instance of…

Machine Learning · Computer Science 2025-01-10 Yujie Zhao , Jose Efraim Aguilar Escamill , Weyl Lu , Huazheng Wang

We identify the average dose-response function (ADRF) for a continuously valued error-contaminated treatment by a weighted conditional expectation. We then estimate the weights nonparametrically by maximising a local generalised empirical…

Statistics Theory · Mathematics 2022-11-30 Wei Huang , Zheng Zhang

Functional principal component analysis has been shown to be invaluable for revealing variation modes of longitudinal outcomes, which serves as important building blocks for forecasting and model building. Decades of research have advanced…

Methodology · Statistics 2024-10-07 Peijun Sang , Dehan Kong , Shu Yang

Principal component regression (PCR) is a widely used two-stage procedure: principal component analysis (PCA), followed by regression in which the selected principal components are regarded as new explanatory variables in the model. Note…

Machine Learning · Statistics 2018-04-03 Shuichi Kawano , Hironori Fujisawa , Toyoyuki Takada , Toshihiko Shiroishi

Estimating the effect of a treatment on a given outcome, conditioned on a vector of covariates, is central in many applications. However, learning the impact of a treatment on a continuous temporal response, when the covariates suffer…

Machine Learning · Computer Science 2019-06-11 Guangyi Zhang , Reza Ashrafi , Anne Juuti , Kirsi Pietiläinen , Pekka Marttinen

This paper establishes the functional average as an important estimand for causal inference. The significance of the estimand lies in its robustness against traditional issues of confounding. We prove that this robustness holds even when…

Statistics Theory · Mathematics 2023-12-04 Shane Sparkes , Erika Garcia , Lu Zhang

This paper introduces \emph{biased mean regression}, estimating the \emph{biased mean}, i.e., $\mathbb{E}[Y] + x$, where $x \in \mathbb{R}$. The approach addresses a fundamental statistical problem that covers numerous applications. For…

Applications · Statistics 2026-03-31 Anton Malandii , Stan Uryasev

Epidemiologists and applied statisticians often believe that relative effect measures conditional on covariates, such as risk ratios and mean ratios, are ``transportable'' across populations. Here, we examine the identification of causal…

Methodology · Statistics 2022-02-24 Issa J. Dahabreh , Sarah E. Robertson , Jon A. Steingrimsson

Pseudo-relevance feedback (PRF) can enhance average retrieval effectiveness over a sufficiently large number of queries. However, PRF often introduces a drift into the original information need, thus hurting the retrieval effectiveness of…

Information Retrieval · Computer Science 2024-01-23 Suchana Datta , Debasis Ganguly , Sean MacAvaney , Derek Greene

Data augmentation is an important technique in training deep neural networks as it enhances their ability to generalize and remain robust. While data augmentation is commonly used to expand the sample size and act as a consistency…

Machine Learning · Computer Science 2025-02-18 Xiliang Yang , Shenyang Deng , Shicong Liu , Yuanchi Suo , Wing. W. Y NG , Jianjun Zhang

Prediction algorithms that quantify the expected benefit of a given treatment conditional on patient characteristics can critically inform medical decisions. Quantifying the performance of treatment benefit prediction algorithms is an…

Methodology · Statistics 2023-05-17 Yuan Xia , Paul Gustafson , Mohsen Sadatsafavi

A treatment may be appropriate for some group (the ``sick" group) on whom it has a positive effect, but it can also have a detrimental effect on subjects from another group (the ``healthy" group). In a non-targeted trial both sick and…

Machine Learning · Computer Science 2025-04-23 Georgios Mavroudeas , Malik Magdon-Ismail , Kristin P. Bennett , Jason Kuruzovich

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

Machine Learning · Computer Science 2025-05-01 Erica Chiang , Divya Shanmugam , Ashley N. Beecy , Gabriel Sayer , Deborah Estrin , Nikhil Garg , Emma Pierson

We propose a method for transfer learning in nonparametric regression using a random forest (RF) with distance covariance-based feature weights, assuming the unknown source and target regression functions are sparsely different. Our method…

Machine Learning · Statistics 2026-03-17 Chenze Li , Subhadeep Paul
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