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Recent years have witnessed remarkable advances in Large Vision-Language Models (LVLMs), which have achieved human-level performance across various complex vision-language tasks. Following LLaVA's paradigm, mainstream LVLMs typically employ…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Jiaqi Liao , Yuwei Niu , Fanqing Meng , Hao Li , Changyao Tian , Yinuo Du , Yuwen Xiong , Dianqi Li , Xizhou Zhu , Li Yuan , Jifeng Dai , Yu Cheng

Large language models have demonstrated remarkable capabilities across various tasks, primarily attributed to the utilization of diversely sourced data. However, the impact of pretraining data composition on model performance remains poorly…

Machine Learning · Computer Science 2025-01-28 Ce Ge , Zhijian Ma , Daoyuan Chen , Yaliang Li , Bolin Ding

The burgeoning interest in developing Large Language Models (LLMs) with up to trillion parameters has been met with concerns regarding resource efficiency and practical expense, particularly given the immense cost of experimentation. This…

Large Language Models (LLMs) have demonstrated strong performance across a wide range of tasks, yet they still struggle with complex mathematical reasoning, a challenge fundamentally rooted in deep structural dependencies. To address this…

Artificial Intelligence · Computer Science 2025-12-01 Lei Zan , Keli Zhang , Ruichu Cai , Lujia Pan

Protein language models (PLMs) have emerged as powerful tools to detect complex patterns of protein sequences. However, the capability of PLMs to fully capture information on protein sequences might be limited by focusing on single…

Machine Learning · Computer Science 2025-05-27 Hazem Alsamkary , Mohamed Elshaffei , Mohamed Elkerdawy , Ahmed Elnaggar

Recent advances in large language models (LLMs) have led to models that tackle diverse molecular tasks, such as chemical reaction prediction and molecular property prediction. Large-scale molecular instruction-tuning datasets have enabled…

Machine Learning · Computer Science 2025-05-27 Chanhui Lee , Hanbum Ko , Yuheon Song , YongJun Jeong , Rodrigo Hormazabal , Sehui Han , Kyunghoon Bae , Sungbin Lim , Sungwoong Kim

Molecular property prediction is a crucial foundation for drug discovery. In recent years, pre-trained deep learning models have been widely applied to this task. Some approaches that incorporate prior biological domain knowledge into the…

Machine Learning · Computer Science 2024-08-20 Tianyu Zhang , Yuxiang Ren , Chengbin Hou , Hairong Lv , Xuegong Zhang

Recent advancements in language modeling have led to the emergence of Large Language Models (LLMs) capable of various natural language processing tasks. Despite their success in text-based tasks, applying LLMs to the speech domain remains…

Computation and Language · Computer Science 2024-04-18 Pavel Denisov , Ngoc Thang Vu

Large language models (LLMs) have achieved substantial progress in processing long contexts but still struggle with long-context reasoning. Existing approaches typically involve fine-tuning LLMs with synthetic data, which depends on…

Computation and Language · Computer Science 2024-11-14 Siheng Li , Cheng Yang , Zesen Cheng , Lemao Liu , Mo Yu , Yujiu Yang , Wai Lam

Large Language Models (LLMs) exhibit emerging in-context learning abilities through prompt engineering. The recent progress in large-scale generative models has further expanded their use in real-world language applications. However, the…

Computation and Language · Computer Science 2024-04-12 Linyi Yang , Shuibai Zhang , Zhuohao Yu , Guangsheng Bao , Yidong Wang , Jindong Wang , Ruochen Xu , Wei Ye , Xing Xie , Weizhu Chen , Yue Zhang

With the success of large language models (LLMs), integrating the vision model into LLMs to build vision-language foundation models has gained much more interest recently. However, existing LLM-based large multimodal models (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Bo He , Hengduo Li , Young Kyun Jang , Menglin Jia , Xuefei Cao , Ashish Shah , Abhinav Shrivastava , Ser-Nam Lim

Developing therapeutics is a lengthy and expensive process that requires the satisfaction of many different criteria, and AI models capable of expediting the process would be invaluable. However, the majority of current AI approaches…

Large Language Models (LLMs), originally developed for natural language processing (NLP), have demonstrated the potential to generalize across modalities and domains. With their in-context learning (ICL) capabilities, LLMs can perform…

Artificial Intelligence · Computer Science 2025-08-26 Nikolaos Pavlidis , Vasilis Perifanis , Symeon Symeonidis , Pavlos S. Efraimidis

This paper introduces the integration of language-specific bi-directional context into a speech large language model (SLLM) to improve multilingual continuous conversational automatic speech recognition (ASR). We propose a character-level…

Computation and Language · Computer Science 2025-07-08 Yizhou Peng , Hexin Liu , Eng Siong Chng

Large language models (LLMs) exhibit remarkable performance improvement through in-context learning (ICL) by leveraging task-specific examples in the input. However, the mechanisms behind this improvement remain elusive. In this work, we…

Computation and Language · Computer Science 2024-02-23 Safoora Yousefi , Leo Betthauser , Hosein Hasanbeig , Raphaël Millière , Ida Momennejad

The goal of protein representation learning is to extract knowledge from protein databases that can be applied to various protein-related downstream tasks. Although protein sequence, structure, and function are the three key modalities for…

Biomolecules · Quantitative Biology 2024-05-14 Eunji Ko , Seul Lee , Minseon Kim , Dongki Kim

Protein language models (PLMs) have demonstrated remarkable capabilities in learning relationships between protein sequences and functions. However, finetuning these large models requires substantial computational resources, often with…

Machine Learning · Computer Science 2025-12-09 Shuo Zhang , Jian K. Liu

Large language models (LLMs) have shown promise in various natural language processing tasks, including their application to proteomics data to classify protein fragments. In this study, we curated a limited mass spectrometry dataset with…

Quantitative Methods · Quantitative Biology 2025-02-28 Taylor A Phillips , Alejandro W. Huskey , Patrick T. Huskey , Seth L. Robia , Peter M. Kekenes-Huskey

Large Language Models (LLMs) have been shown to organize the representations of input sequences into straighter neural trajectories in their deep layers, which has been hypothesized to facilitate next-token prediction via linear…

Computation and Language · Computer Science 2026-02-02 Eghbal A. Hosseini , Yuxuan Li , Yasaman Bahri , Declan Campbell , Andrew Kyle Lampinen

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon