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Related papers: RNA-GPT: Multimodal Generative System for RNA Sequ…

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The remarkable multimodal capabilities demonstrated by OpenAI's GPT-4 have sparked significant interest in the development of multimodal Large Language Models (LLMs). A primary research objective of such models is to align visual and…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Yanda Li , Chi Zhang , Gang Yu , Zhibin Wang , Bin Fu , Guosheng Lin , Chunhua Shen , Ling Chen , Yunchao Wei

In this paper, we present CORE-GPT, a novel question-answering platform that combines GPT-based language models and more than 32 million full-text open access scientific articles from CORE. We first demonstrate that GPT3.5 and GPT4 cannot…

Computation and Language · Computer Science 2023-07-11 David Pride , Matteo Cancellieri , Petr Knoth

Knowledge Tracing (KT) infers a student's knowledge state from past interactions to predict future performance. Conventional Deep Learning (DL)-based KT models are typically tied to platform-specific identifiers and latent representations,…

Artificial Intelligence · Computer Science 2026-04-23 Zhiyi Duan , Hongyu Yuan , Rui Liu

Proteins play a vital role in biological processes and are indispensable for living organisms. Accurate representation of proteins is crucial, especially in drug development. Recently, there has been a notable increase in interest in…

Biomolecules · Quantitative Biology 2026-05-28 Dan Kalifa , Uriel Singer , Kira Radinsky

Popular solutions to Named Entity Recognition (NER) include conditional random fields, sequence-to-sequence models, or utilizing the question-answering framework. However, they are not suitable for nested and overlapping spans with large…

Computation and Language · Computer Science 2022-03-08 Hagen Soltau , Izhak Shafran , Mingqiu Wang , Laurent El Shafey

Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

Computation and Language · Computer Science 2024-10-28 Shubham Vatsal , Ayush Singh

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

Existing question answering (QA) systems owe much of their success to large, high-quality training data. Such annotation efforts are costly, and the difficulty compounds in the cross-lingual setting. Therefore, prior cross-lingual QA work…

Computation and Language · Computer Science 2023-10-18 Bryan Li , Chris Callison-Burch

Feature transformation plays a critical role in enhancing machine learning model performance by optimizing data representations. Recent state-of-the-art approaches address this task as a continuous embedding optimization problem, converting…

Machine Learning · Computer Science 2025-08-29 Yang Gao , Dongjie Wang , Scott Piersall , Ye Zhang , Liqiang Wang

RNA-seq allows detection and precise quantification of transcripts, provides comprehensive understanding of exon/intron boundaries, aids discovery of alternatively spliced isoforms and fusion transcripts along with measurement of…

Genomics · Quantitative Biology 2013-06-03 Prachi Jain , Neeraja M. Krishnan , Binay Panda

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

While large language models (LLMs) have made considerable advancements in understanding and generating unstructured text, their application in structured data remains underexplored. Particularly, using LLMs for complex reasoning tasks on…

Computation and Language · Computer Science 2023-10-18 Jiho Kim , Yeonsu Kwon , Yohan Jo , Edward Choi

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale…

Quantitative Methods · Quantitative Biology 2024-12-23 Heming Zhang , Di Huang , Yixin Chen , Fuhai Li

Transformer architectures have facilitated the development of large-scale and general-purpose sequence models for prediction tasks in natural language processing and computer vision, e.g., GPT-3 and Swin Transformer. Although originally…

Machine Learning · Computer Science 2023-06-27 Muning Wen , Runji Lin , Hanjing Wang , Yaodong Yang , Ying Wen , Luo Mai , Jun Wang , Haifeng Zhang , Weinan Zhang

We introduce REALTIME QA, a dynamic question answering (QA) platform that announces questions and evaluates systems on a regular basis (weekly in this version). REALTIME QA inquires about the current world, and QA systems need to answer…

Computation and Language · Computer Science 2024-02-29 Jungo Kasai , Keisuke Sakaguchi , Yoichi Takahashi , Ronan Le Bras , Akari Asai , Xinyan Yu , Dragomir Radev , Noah A. Smith , Yejin Choi , Kentaro Inui

The emergence of models like GPTs, Claude, LLaMA, and Qwen has reshaped AI applications, presenting vast new opportunities across industries. Yet, the integration of tabular data remains notably underdeveloped, despite its foundational role…

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Contemporary glioma diagnosis integrates molecular features with histopathology to guide clinical decision-making. However, in clinical settings, divergent imaging protocols result in incomplete MRI sequences, leading to two primary…

Image and Video Processing · Electrical Eng. & Systems 2026-05-25 Pengfei Song , Fangjin Liu , Wenwen Zeng , Yonghuang Wu , Chengqian Zhao , Feiyu Yin , Xuan Xie , Jinhua Yu

Large language models (LLMs) have emerged as valuable tools for many natural language understanding tasks. In safety-critical applications such as healthcare, the utility of these models is governed by their ability to generate outputs that…

Computation and Language · Computer Science 2023-03-31 Varun Nair , Elliot Schumacher , Geoffrey Tso , Anitha Kannan