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Related papers: RNA-GPT: Multimodal Generative System for RNA Sequ…

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The gene set analysis (GSA) is a foundational approach for uncovering the molecular functions associated with a group of genes. Recently, LLM-powered methods have emerged to annotate gene sets with biological functions together with…

Genomics · Quantitative Biology 2025-09-16 Zhizheng Wang , Yifan Yang , Qiao Jin , Zhiyong Lu

Summary: BGT is a compact format, a fast command line tool and a simple web application for efficient and convenient query of whole-genome genotypes and frequencies across tens to hundreds of thousands of samples. On real data, it encodes…

Genomics · Quantitative Biology 2017-08-07 Heng Li

Generative Pre-trained Transformer 4 (GPT-4) is the fourth-generation language model in the GPT series, developed by OpenAI, which promises significant advancements in the field of natural language processing (NLP). In this research…

Computation and Language · Computer Science 2023-05-08 Jawid Ahmad Baktash , Mursal Dawodi

Expert feedback lays the foundation of rigorous research. However, the rapid growth of scholarly production and intricate knowledge specialization challenge the conventional scientific feedback mechanisms. High-quality peer reviews are…

This paper presents the development and application of a Large Language Model Retrieval-Augmented Generation (LLM-RAG) system tailored for nanotechnology research. The system leverages the capabilities of a sophisticated language model to…

Computation and Language · Computer Science 2025-03-03 Achuth Chandrasekhar , Omid Barati Farimani , Olabode T. Ajenifujah , Janghoon Ock , Amir Barati Farimani

Discovering new materials better suited to specific purposes is an important issue in improving the quality of human life. Here, a neural network that creates molecules that meet some desired conditions based on a deep understanding of…

Machine Learning · Computer Science 2022-02-15 Hyunseung Kim , Jonggeol Na , Won Bo Lee

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

Rare diseases (RDs) are collectively common and affect 300 million people worldwide. Accurate phenotyping is critical for informing diagnosis and treatment, but RD phenotypes are often embedded in unstructured text and time-consuming to…

Computation and Language · Computer Science 2024-06-28 Cathy Shyr , Yan Hu , Paul A. Harris , Hua Xu

Large language models (LLMs) have notably enhanced the fluency and diversity of machine-generated text. However, this progress also presents a significant challenge in detecting the origin of a given text, and current research on detection…

Computation and Language · Computer Science 2023-10-05 Xianjun Yang , Wei Cheng , Yue Wu , Linda Petzold , William Yang Wang , Haifeng Chen

Since the launch of ChatGPT at the end of 2022, generative dialogue models represented by ChatGPT have quickly become essential tools in daily life. As user expectations increase, enhancing the capability of generative dialogue models to…

Computation and Language · Computer Science 2024-09-02 Yuetong Zhao , Hongyu Cao , Xianyu Zhao , Zhijian Ou

Given the increasing availability of RNA-seq data and its complex and heterogeneous nature, there has been growing interest in applying AI/machine learning methodologies to work with such data modalities. However, because omics data is…

Genomics · Quantitative Biology 2023-11-22 Kevin Li , Danko Nikolić , Vjekoslav Nikolić , Davor Andrić , Lauren M. Sanders , Sylvain V. Costes

Using natural language processing (NLP) technologies to develop medical chatbots makes the diagnosis of the patient more convenient and efficient, which is a typical application in healthcare AI. Because of its importance, lots of research…

Computation and Language · Computer Science 2023-12-06 Ke Liang , Sifan Wu , Jiayi Gu

Noncoding RNAs are integral to a wide range of biological processes, including translation, gene regulation, host-pathogen interactions and environmental sensing. While genomics is now a mature field, our capacity to identify noncoding RNA…

ChatGPT has achieved remarkable success in natural language understanding. Considering that recommendation is indeed a conversation between users and the system with items as words, which has similar underlying pattern with ChatGPT, we…

Information Retrieval · Computer Science 2024-04-16 Yabin Zhang , Wenhui Yu , Erhan Zhang , Xu Chen , Lantao Hu , Peng Jiang , Kun Gai

Narrative generation is an open-ended NLP task in which a model generates a story given a prompt. The task is similar to neural response generation for chatbots; however, innovations in response generation are often not applied to narrative…

Computation and Language · Computer Science 2021-07-09 Alexandra DeLucia , Aaron Mueller , Xiang Lisa Li , João Sedoc

This study presents a comparative analysis of three Generative Pre-trained Transformer (GPT) solutions in a question and answer (Q&A) setting: Drug-GPT 3, Drug-GPT 4, and ChatGPT, in the context of healthcare applications. The objective is…

Computation and Language · Computer Science 2023-08-01 Giorgos Lysandrou , Roma English Owen , Kirsty Mursec , Grant Le Brun , Elizabeth A. L. Fairley

Single-cell RNA sequencing (scRNA-seq) technology enables systematic delineation of cellular states and interactions, providing crucial insights into cellular heterogeneity. Building on this potential, numerous computational methods have…

Genomics · Quantitative Biology 2025-11-11 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Ran Zhang , Gaoyang Li , Hanyu Xie , Jiajia Wang , Yuanchun Zhou , Pengfei Wang

Distantly supervised relation extraction is widely used to extract relational facts from text, but suffers from noisy labels. Current relation extraction methods try to alleviate the noise by multi-instance learning and by providing…

Computation and Language · Computer Science 2019-06-21 Christoph Alt , Marc Hübner , Leonhard Hennig

Visual Question Answering (VQA) in remote sensing (RS) is pivotal for interpreting Earth observation data. However, existing RS VQA datasets are constrained by limitations in annotation richness, question diversity, and the assessment of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Xing Zi , Jinghao Xiao , Yunxiao Shi , Xian Tao , Jun Li , Ali Braytee , Mukesh Prasad

In the expanding field of language model applications, medical knowledge representation remains a significant challenge due to the specialized nature of the domain. Large language models, such as GPT-4, obtain reasonable scores on medical…

Computation and Language · Computer Science 2024-05-24 Julien Khlaut , Corentin Dancette , Elodie Ferreres , Alaedine Bennani , Paul Hérent , Pierre Manceron
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