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Accurate segmentation of anatomical structures in volumetric medical images is crucial for clinical applications, including disease monitoring and cancer treatment planning. Contemporary interactive segmentation models, such as Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Tatyana Shmykova , Leila Khaertdinova , Ilya Pershin

Purpose: The Segment Anything Model (SAM) promises to ease the annotation bottleneck in medical segmentation, but overlapping anatomy and blurred boundaries make its point prompts ambiguous, leading to cycles of manual refinement to achieve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Adrien Meyer , Lorenzo Arboit , Giuseppe Massimiani , Shih-Min Yin , Didier Mutter , Nicolas Padoy

Segmentation is central to clinical diagnosis and monitoring, yet the reliability of modern foundation models in medical imaging still depends on the availability of precise prompts. The Segment Anything Model (SAM) offers powerful…

Semantic segmentation is an important topic in computer vision with many relevant application in Earth observation. While supervised methods exist, the constraints of limited annotated data has encouraged development of unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Pratik Vora , Sudipan Saha

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

The Segment Anything Model (SAM) achieves remarkable promptable segmentation given high-quality prompts which, however, often require good skills to specify. To make SAM robust to casual prompts, this paper presents the first comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Qi Fan , Xin Tao , Lei Ke , Mingqiao Ye , Yuan Zhang , Pengfei Wan , Zhongyuan Wang , Yu-Wing Tai , Chi-Keung Tang

Grounding DINO and the Segment Anything Model (SAM) have achieved impressive performance in zero-shot object detection and image segmentation, respectively. Together, they have a great potential to revolutionize applications in zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Fuseini Mumuni , Alhassan Mumuni

Precision medicine, such as patient-adaptive treatments assisted by medical image analysis, poses new challenges for segmentation algorithms in adapting to new patients, due to the large variability across different patients and the limited…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Chenhui Zhao , Liyue Shen

The Segment Anything Model 2 (SAM2) has demonstrated remarkable promptable visual segmentation capabilities in video data, showing potential for extension to medical image segmentation (MIS) tasks involving 3D volumes and temporally…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Meng Lan , Lefei Zhang , Xiaomeng Li

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

Although SAM-based single-source domain generalization models for medical image segmentation can mitigate the impact of domain shift on the model in cross-domain scenarios, these models still face two major challenges. First, the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Huanli Zhuo , Leilei Ma , Haifeng Zhao , Shiwei Zhou , Dengdi Sun , Yanping Fu

The ability to segment objects based on open-ended language prompts remains a critical challenge, requiring models to ground textual semantics into precise spatial masks while handling diverse and unseen categories. We present OpenWorldSAM,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shiting Xiao , Rishabh Kabra , Yuhang Li , Donghyun Lee , Joao Carreira , Priyadarshini Panda

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

The recent Segment Anything Model (SAM) represents a big leap in scaling up segmentation models, allowing for powerful zero-shot capabilities and flexible prompting. Despite being trained with 1.1 billion masks, SAM's mask prediction…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Lei Ke , Mingqiao Ye , Martin Danelljan , Yifan Liu , Yu-Wing Tai , Chi-Keung Tang , Fisher Yu

Promptable foundation models such as the Segment Anything Model (SAM) produce high-quality masks but remain semantically blind, relying on external prompts to specify categories. Existing vision-language approaches address this limitation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Shayan Jalilian , Abdul Bais

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

As large-scale foundation models trained on billions of image--mask pairs covering a vast diversity of scenes, objects, and contexts, SAM and its upgraded version, SAM~2, have significantly influenced multiple fields within computer vision.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Xiaoqi Zhao , Youwei Pang , Shijie Chang , Yuan Zhao , Lihe Zhang , Chenyang Yu , Hanqi Liu , Jiaming Zuo , Jinsong Ouyang , Weisi Lin , Georges El Fakhri , Huchuan Lu , Xiaofeng Liu

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

The recent advancements in large-scale pre-training techniques have significantly enhanced the capabilities of vision foundation models, notably the Segment Anything Model (SAM), which can generate precise masks based on point and box…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Anqi Zhang , Guangyu Gao , Jianbo Jiao , Chi Harold Liu , Yunchao Wei