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Variable selection methods are required in practical statistical modeling, to identify and include only the most relevant predictors, and then improving model interpretability. Such variable selection methods are typically employed in…

Multivariate count data are commonly encountered through high-throughput sequencing technologies in bioinformatics, text mining, or in sports analytics. Although the Poisson distribution seems a natural fit to these count data, its…

Computation · Statistics 2020-04-16 Sanjeena Subedi , Ryan Browne

When studying ecosystems, hierarchical trees are often used to organize entities based on proximity criteria, such as the taxonomy in microbiology, social classes in geography, or product types in retail businesses, offering valuable…

Methodology · Statistics 2025-06-27 Alexandre Chaussard , Anna Bonnet , Elisabeth Gassiat , Sylvain Le Corff

Modeling data with multivariate count responses is a challenging problem due to the discrete nature of the responses. Existing methods for univariate count responses cannot be easily extended to the multivariate case since the dependency…

Methodology · Statistics 2016-08-15 Hao Wu , Xinwei Deng , Naren Ramakrishnan

The Poisson log-normal model is a latent variable model that provides a generic framework for the analysis of multivariate count data. Inferring its parameters can be a daunting task since the conditional distribution of the latent…

Computation · Statistics 2026-05-19 Julien Stoehr , Stephane S. Robin

Multivariate count models are often justified by their ability to capture latent dependence, but researchers receive little guidance on when this added structure improves on simpler penalized marginal Poisson regression. We study this…

Machine Learning · Computer Science 2026-04-07 Daniel Agyapong , Julien Chiquet , Jane Marks , Toby Dylan Hocking

Generalized linear models are a popular tool in applied statistics, with their maximum likelihood estimators enjoying asymptotic Gaussianity and efficiency. As all models are wrong, it is desirable to understand these estimators' behaviours…

Methodology · Statistics 2024-12-10 Elliot H. Young , Rajen D. Shah

High-dimensional data of discrete and skewed nature is commonly encountered in high-throughput sequencing studies. Analyzing the network itself or the interplay between genes in this type of data continues to present many challenges. As…

Methodology · Statistics 2017-12-01 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Sanjeena Subedi

A validated simulation model primarily requires performing an appropriate input analysis mainly by determining the behavior of real-world processes using probability distributions. In many practical cases, probability distributions of the…

Applications · Statistics 2014-09-01 Issac Shams , Saeede Ajorlou , Kai Yang

Simulation-based inference techniques are indispensable for parameter estimation of mechanistic and simulable models with intractable likelihoods. While traditional statistical approaches like approximate Bayesian computation and Bayesian…

Methodology · Statistics 2024-03-08 Ryan P. Kelly , David J. Nott , David T. Frazier , David J. Warne , Chris Drovandi

In this paper, we study the problem of computing a Principal Component Analysis of data affected by Poisson noise. We assume samples are drawn from independent Poisson distributions. We want to estimate principle components of a fixed…

Methodology · Statistics 2021-05-25 Toby Kenney , Tianshu Huang , Hong Gu

In the matter of selection of sample time points for the estimation of the power spectral density of a continuous time stationary stochastic process, irregular sampling schemes such as Poisson sampling are often preferred over regular…

Statistics Theory · Mathematics 2010-07-19 Radhendushka Srivastava , Debasis Sengupta

Species distribution modeling (SDM) plays a crucial role in investigating habitat suitability and addressing various ecological issues. While likelihood analysis is commonly used to draw ecological conclusions, it has been observed that its…

Methodology · Statistics 2023-07-03 Yusuke Saigusa , Shinto Eguchi , Osamu Komori

This paper is devoted to the multivariate estimation of a vector of Poisson means. A novel loss function that penalises bad estimates of each of the parameters and the sum (or equivalently the mean) of the parameters is introduced. Under…

Statistics Theory · Mathematics 2019-04-25 Emil Aas Stoltenberg , Nils Lid Hjort

Qualifying gene and isoform expression is one of the primary tasks for RNA-Seq experiments. Given a sequence of counts representing numbers of reads mapped to different positions (exons and junctions) of isoforms, methods based on Poisson…

Applications · Statistics 2014-10-27 Jun Li , Hui Jiang

High-dimensional count data poses significant challenges for statistical analysis, necessitating effective methods that also preserve explainability. We focus on a low rank constrained variant of the Poisson log-normal model, which relates…

Optimization and Control · Mathematics 2025-06-17 Bastien Batardière , Julien Chiquet , Joon Kwon , Julien Stoehr

In applications such as gene regulatory network analysis based on single-cell RNA sequencing data, samples often come from a mixture of different populations and each population has its own unique network. Available graphical models often…

Methodology · Statistics 2022-12-08 Junjie Tang , Changhu Wang , Feiyi Xiao , Ruibin Xi

The likelihood functions for discretely observed nonlinear continuous-time models based on stochastic differential equations are not available except for a few cases. Various parameter estimation techniques have been proposed, each with…

Methodology · Statistics 2025-04-17 Predrag Pilipovic , Adeline Samson , Susanne Ditlevsen

We introduce the Poisson Log-Normal Graphical Model for count data, and present a normality transformation for data arising from this distribution. The model and transformation are feasible for high-throughput microRNA (miRNA) sequencing…

Computation · Statistics 2017-08-16 David Sinclair , Giles Hooker

Modeling count data is important in physics and other scientific disciplines, where measurements often involve discrete, non-negative quantities such as photon or neutrino detection events. Traditional parametric approaches can be trained…

Data Analysis, Statistics and Probability · Physics 2026-02-10 Anushka Saha , Abhijith Gandrakota , Alexandre V. Morozov
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